Lupus anticoagulant (LA) was evaluated using a three-step procedure according to the guidelines of The International Society of Thrombosis and Haemostasis [31 ]. To clarify, dilute Russell’s viper venom time (dRVVT; LA1-screen; Siemens, Germany) and a sensitive aPTT (PTT LA; Diagnostica Stago, France) were used for screening, whereas LA2-confirm (Siemens, Germany) and Staclot LA (Diagnostica Stago, USA) were run to affirm the result. Levels of anticardiolipin (ACL) and anti-β2-glycoprotein I (Aβ2GPI) antibodies, IgM and IgG classes, were performed with commercially available immunoenzymatic assays (QUANTA Lite® aCL and aβ2GPI (Inova Diagnostics, San Diego, USA)).
La1 screen
Manufactured by Siemens
Sourced in Germany
The LA1-screen is a laboratory equipment product offered by Siemens. It is designed to display and monitor data and information related to various laboratory processes and procedures. The core function of the LA1-screen is to provide a visual interface for users to access and interact with relevant data.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using la1 screen
1
Lupus Anticoagulant Evaluation Protocol
2
Lupus Anticoagulant Detection Assay
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Lupus anticoagulant (LA) was determined in a three-step procedure according to the guidelines of The International Society of Thrombosis and Haemostasis, as described elsewhere [13] (link). Briefly, diluted Russell's viper venom time (dRVVT; LA1-screen; Siemens, Germany) and a sensitive aPTT (PTT LA; Diagnostica Stago, France) were used for screening, whereas LA2-confirm (Siemens, Germany) and Staclot LA (Diagnostica Stago, USA) were run for the confirmation. Reference values for each test were established using 99th percentile of the healthy population. Commercially available immunoenzymatic assays were applied to determine anticardiolipin (aCL) and anti-β2-glycoprotein I (aβ2GPI) antibodies (QUANTA Lite® aCL and aβ2GPI (Inova Diagnostics, San Diego, USA)).
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