Magnetom prisma mri system

All participants were imaged on a 3T Siemens (Erlangen, Germany) Magnetom Prisma MRI System using a 64-channel head coil. The MRI protocol included a TRUST sequence with repetition time (TR) = 3000 ms, inversion time (TI) = 1020 ms, voxel size = 3.44 × 3.44 × 5 mm³, matrix size = 64 × 64 × 1, effective echo time (eTE) = 0, 40, 80, 160 ms, label slab = 100 mm and 3 averages. This was followed by a multi-parametric mapping (MPM) acquisition comprised of three fast low angle shot (FLASH) GRE sequences with respective magnetization transfer (MT), proton density (PD) and T₁ weighting. The PD-weighted sequence parameters were: TR = 24.5 ms, TE₁ = 2.34 ms, ΔTE = 2.34 ms, echoes = 8, flip angle = 6°, voxel size = 1 mm³ isotropic. T₁-weighting was introduced by increasing the flip angle to 20° with all other parameters kept the same. MT-weighting was introduced by applying off-resonance saturation pulses prior to excitation with the number of echoes reduced to 6 to maintain consistent TR.
During the MRI examination, peripheral oxygen saturation (SpO₂) was measured using a pulse oximeter. Blood T1 was estimated from blood hematocrit and measured SpO₂ (Hales et al., 2016 (link)). In one SCA subject, pulse oximetry measures of SpO₂ were not available and the mean SpO₂ across SCA patients (97.47%) was used.

All MRI data were acquired using a 3T Siemens MAGNETOM Prisma MRI System equipped with a 32 channel receive-only head coil.

In the United Kingdom, 16-y-old adolescents can choose to stop studying math as part of their advanced, i.e., A-level, subjects. Towards a single dependent variable in the study, a math group consisted of 72 students who engaged in A-level maths. A non-math group consisted of 51 students who were not engaged in A-level maths. The used 123 MRI data were acquired at the Oxford Centre for Function MRI of the Brain (FMRIB) on 3T Siemens MAGNETOM Prisma MRI System equipped with a 32-channel receive-only head coil. And anatomical high-resolution T1-weighted scans were acquired using an MPRAGE sequence consisting of 192 slices, where repetition time $TR=1900$ ms, echo time $TE=3.97$ ms, and voxel $size=1\times 1\times 1$ mm. The voxels of interest (VOI) of size $20\times 20\times 20$ mm were manually centered in the MFG based on the individual’s T1-weighted images while the participant was lying down in the MR scanner [3 (link)]. Slices of the T1-weighted MRI and the left MFG region in three different directions were shown in Figure 1.

All MRI data were acquired at the Oxford Centre for Functional MRI of the Brain (FMRIB) on a 3T Siemens MAGNETOM Prisma MRI System equipped with a 32-channel receive-only head coil.

All MRI data were acquired at the Oxford Centre for Functional MRI of the Brain (FMRIB) on a 3T Siemens (Germany) MAGNETOM Prisma MRI System equipped with a 32 channel receive-only head coil.

All MRI data were acquired at the Oxford Centre for Functional MRI of the Brain (FMRIB) on a 3T Siemens MAGNETOM Prisma MRI System equipped with a 32 channel receive‐only head coil. Anatomical high‐resolution T1‐weighted scans were acquired (MPRAGE sequence: TR = 1,900 ms; TE = 3.97 ms; 192 slices; voxel size = 1 × 1 × 1 mm).

A 3-T MAGNETOM Prisma MRI system (Siemens) was used to acquire both structural T1-weighted images (repetition time = 2250 ms, echo time = 3.06 ms, flip angle = 9°, thickness = 1 mm, field of view = 256 mm, slice gap = 0 mm) and T2*-weighted echo planar images (repetition time = 2000 ms, echo time = 30 ms, flip angle = 80°, slices = 56, thickness = 2.5 mm, field of view = 200 mm, slice gap = 0 mm, multi-slice mode, interleaved).