All reagents were purchased from Sigma Aldrich unless otherwise indicated. ERK inhibitor SCH772984 (14 (link)) was purchased from Active Biochem and used at a concentration of 1000 nM for in vitro experiments. The MEK inhibitor trametinib was purchased from Selleckchem and used at a concentration of 100 nM for in vitro experiments. All drugs were reconstituted in sterile, dry DMSO, aliquoted, and stored at 80 °C until further use.
Sch772984
Manufactured by Active Motif
SCH772984 is a small molecule inhibitor that targets the ERK1/2 kinases. It functions by binding and inhibiting the enzymatic activity of ERK1 and ERK2, which are key players in the MAPK signaling pathway.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using sch772984
1
Inhibitors of ERK and MEK Signaling
2
BRD4, ERK, and MEK Inhibitor Assay
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