Serial quantitative SPECT/CT images for two patients receiving 177Lu-DOTATATE therapy were obtained from the Deep Blue database. The first patient being male, 64 years of age, and imaged following the second cycle of 177Lu-DOTATATE treatment (7.21 GBq). Two lesions >2 cm3 were identified for this patient based on radiologist assessment. The second patient being female, 63 years of age, imaged after the first cycle of 177Lu-DOTATATE treatment (7.31 GBq). For the second patient, four lesions were identified based on radiologist assessment, and the patient has no spleen. Both patients were imaged on an Intevo™ SPECT/CT scanner (Siemens®) and images reconstructed with xSPECT Quant™.
Intevo spect ct scanner
Manufactured by Siemens
Sourced in Netherlands
The Intevo™ SPECT/CT scanner is a medical imaging device developed by Siemens. It combines single-photon emission computed tomography (SPECT) and computed tomography (CT) technologies to provide hybrid imaging capabilities. The core function of the Intevo™ SPECT/CT scanner is to capture detailed images of the body's internal structures and physiological processes.
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Lab products found in correlation
2 protocols using intevo spect ct scanner
1
Quantitative SPECT/CT Dosimetry of Lu-177-DOTATATE Therapy
2
Dual-isotope SPECT/CT and planar subtraction imaging protocol
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Planar pinhole and SPECT/CT images were acquired on a Philips Skylight gamma-camera (Philips Healthcare, the Netherlands) and a Siemens Symbia Intevo SPECT/CT scanner (Siemens Healthineers, Erlangen, Germany) in the Department of Nuclear Medicine, Herlev and Gentofte Hospital, Denmark. The acquisition details are described elsewhere [4 (link)]. Planar subtraction images were analyzed using Oasis software (Segami, Columbia, New York, NY, USA). 123I images were subtracted from 99mTc-MIBI images with increasing multiplication until counts in the thyroid bed were equal to 99mTc background counts on the neck. Subtraction SPECT/CT was done by subtracting the reconstructed, attenuation-corrected 123I dataset from the 99Tc SPECT datasets using MIM (MIM software Inc., Cleveland, OH, USA) in a customized workflow where the subtraction factor could be set and modified at the reader’s discretion. All subtraction planar and SPECT/CT scans were read by the same experienced specialist in nuclear medicine.
SeeFigure 1 and Figure 2 for images (same patient as Figure 3 ).
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