Hyaluronic acid ha

Manufactured by Fujifilm

Sourced in Japan

Hyaluronic acid (HA) is a naturally occurring polysaccharide found in various tissues of the body. It is a key component of the extracellular matrix and plays a crucial role in maintaining tissue hydration and structure. HA is a versatile molecule with diverse applications in the field of biotechnology and laboratory research.

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Lab products found in correlation

2 protocols using hyaluronic acid ha

Serum Biomarkers for Liver Fibrosis

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Serum concentrations of ATX were measured using a two‐site enzyme immunoassay and an automated immunoassay analyzer (Tosoh, Tokyo, Japan). Immunoassay kits were used to measure the serum concentrations of Wisteria floribunda agglutinin‐positive Mac‐2‐binding protein (WFA(+)‐M2BP; HISCL, Sysmex, Hyogo, Japan), hyaluronic acid (HA; Wako Pure Chemical Industries, Tokyo, Japan), and type IV collagen 7S (IVC7S; Sceti Medical Labo K.K., Tokyo, Japan). Additional surrogate blood indices of liver fibrosis assessed at enrollment were the fibrosis‐4 index and the aspartate aminotransferase (AST)‐to‐platelet ratio, which were calculated as follows: (age [years] × AST [IU/L]/platelet count [10⁹/L] × alanine aminotransferase [ALT] [IU/L]^1/2)23 and (AST/upper limit of normal; 40 [IU/L]) × (100/platelet count [10⁹/L]),24 respectively.

Ando W., Yokomori H., Kaneko F., Kaneko M., Igarashi K, & Suzuki H. (2018). Serum Autotaxin Concentrations Reflect Changes in Liver Stiffness and Fibrosis After Antiviral Therapy in Patients with Chronic Hepatitis C. Hepatology Communications, 2(9), 1111-1122.

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Extraction and Analysis of Marine Collagen

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Shortbill spearfish (Tetrapturus angustirostris) and striped marlin (Kajikia audax) were purchased in the summer from the fish market of Kesen-Numa city, Miyagi Prefecture, Japan.
Pepsin (1:10,000) (from Porcine Stomach Mucosa, EC 3.4.23.1), sodium hydroxide (NaOH), acetic acid, hydrochloric acid (HCl), sodium chloride (NaCl), tris-(hydroxymethyl)-aminomethane (Tris), hydroxyproline (4-hydroxy-1-proline), chloramine T, isopropanol, ρ-dimethylaminobenzaldehyde (ρ-DMAB), acetonitrile (ACN), trifluoroacetic acid (TFA), protease (from Streptomyces griseus, EC 3.4.24.31), papain (form Carica papaya, EC 3.4.22.2), trinitro-benzene-sulfonic acid (TNBS), hyaluronic acid (HA), bovine serum albumin (BSA), and hyaluronidase (from bovine testes, EC 3.2.1.35) were purchased from FUJIFILM Wako Pure Chemical Industries, Ltd. (Osaka, Japan). Trypsin (from porcine pancreas, EC 3.4.21.4), α-chymoTrypsin (from bovine pancreas, EC 3.4.21.1), collagenase (from Clostridium histolyticum, EC 232-582-9), and L-leucine were purchased from Sigma-Aldrich Co. LLC., St. Louis, MO, USA.

Han Q.Y., Koyama T., Watabe S., Nagashima Y, & Ishizaki S. (2023). Isolation and Characterization of Collagen and Collagen Peptides with Hyaluronidase Inhibition Activity Derived from the Skin of Marlin (Istiophoridae). Molecules, 28(2), 889.

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