Ag120

Manufactured by Selleck Chemicals

AG120 is a specialized laboratory instrument used for the analytical separation and purification of chemical substances. It employs a technique called affinity chromatography to selectively isolate target analytes from complex mixtures. The core function of AG120 is to facilitate the efficient and accurate separation and concentration of desired compounds for further analysis or purification.

Automatically generated - may contain errors

Lab products found in correlation

Ag 221, by Selleck Chemicals (1 mentions) Pci 34051, by Selleck Chemicals (1 mentions) Ar 42, by Selleck Chemicals (1 mentions) Dasatinib, by Selleck Chemicals (1 mentions) Erlotinib, by Selleck Chemicals (1 mentions) α ketoglutaric acid sodium salt, by Merck Group (1 mentions) Diaphorase from clostridium kluyveri, by Merck Group (1 mentions) Dl isocitric acid trisodium salt hydrate, by Merck Group (1 mentions) β nicotinamide adenine dinucleotide 2 phosphate reduced tetrasodium salt hydrate nadph, by Merck Group (1 mentions) Pdgfrα, by Thermo Fisher Scientific (1 mentions) Quizartinib, by Selleck Chemicals (1 mentions) Atp disodium salt hydrate, by Merck Group (1 mentions) β nicotinamide adenine dinucleotide phosphate hydrate nadp, by Merck Group (1 mentions) Pdgfrβ, by Thermo Fisher Scientific (1 mentions) Fgfr3, by Thermo Fisher Scientific (1 mentions) Ruxolitinib, by Selleck Chemicals (1 mentions) Ag490, by Selleck Chemicals (1 mentions) Resazurin sodium salt, by Merck Group (1 mentions)

2 protocols using ag120

In Vivo Study Compound Formulation

Check if the same lab product or an alternative is used in the 5 most similar protocols

KPT-2974, AR-42, AG221, AG120, and PCI-34051 were purchased from Selleckchem. For in vivo study, AR-42 was formulated in 0.5% methylcellulose [w/v] and 0.1% Tween-80 [v/v] in sterile water.

Zhang P., Brinton L., Williams K., Sher S., Orwick S., Tzung-Huei L., Mims A., Coss C., Kulp S., Youssef Y., Chan W.K., Mitchell S., Mustonen A., Cannon M., Phillips H., Lehman A., Kauffman T., Beaver L., Canfield D., Grieselhuber N., Alinari L., Sampath D., Yan P.S., Byrd J.C., Blachly J.S, & Lapalombella R. (2021). Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research.

+ Open protocol

+ Expand

Kinase Activity Assay Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

Myelin basic protein from bovine, DL-isocitric acid trisodium salt hydrate, β-nicotinamide adenine dinucleotide phosphate hydrate (NADP⁺), β-nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate (NADPH), α-ketoglutaric acid sodium salt, diaphorase from Clostridium kluyveri, resazurin sodium salt, and ATP disodium salt hydrate were purchased from Sigma-Aldrich. Ketoglutaric acid sodium salt, α-[1-¹⁴C], 50μCi (1.85MBq) and glucose, D-[U-¹⁴C]- were from PerkinElmer. Glutamine L-[5-¹⁴C] and isocitric acid[³H(G)] were from ARC. Inhibitors including dovitinib (TKI-258, CHIR-258), imatinib, AG-490, quizartinib, PP2, erlotinib, ruxolitinib, dasatinib and AG-120 were purchased from Selleckchem. Recombinant proteins including FLT3, SRC, PDGFRα, PDGFRβ, EGFR, MET, KIT, JAK2, FGFR3 and ABL1 were purchased from Thermo Fisher.

Chen D., Xia S., Wang M., Lin R., Li Y., Mao H., Aguiar M., Famulare C.A., Shih A.H., Brennan C.W., Gao X., Pan Y., Liu S., Fan J., Jin L., Song L., Zhou A., Mukherjee J., Pieper R.O., Mishra A., Peng J., Arellano M., Blum W.G., Lonial S., Boggon T.J., Levine R.L, & Chen J. (2019). Mutant and wild-type isocitrate dehydrogenase 1 share enhancing mechanisms involving distinct tyrosine kinase cascades in cancer. Cancer discovery, 9(6), 756-777.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!