The MRI imaging was performed using a 1.5 T Siemens Avanto MRI machine (Siemens Healthcare GmbH, Erlangen, Germany). The patients were examined using a standard knee MRI protocol [13 (link)] that was developed and used at Oslo University Hospital and included T2 mapping and a dGEMRIC [14 (link)]. The patients were scanned with all of the different sequences mentioned in Additional file 1 , except for the last sequence of the T1 map [15 (link)]. Then, they were injected with a 2 mmol/kg bodyweight dose of Gadopentetate dimedlumine, Gd-DPA (Magnevist, Berlex Laboratories, Wayne, NJ, US) [16 (link)]. The contrast agent was injected in an antecubital vein. After the injection, the patients walked for 15 min and then rested for approximately 75 min before the last scan was performed [17 (link)].
Avanto mri machine
Manufactured by Siemens
Sourced in Germany
The Avanto MRI machine is a magnetic resonance imaging (MRI) system developed by Siemens. It is designed to perform non-invasive imaging of the body's internal structures. The Avanto MRI machine uses a strong magnetic field and radio waves to generate detailed images of the human body, which can be used for diagnostic and clinical purposes.
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Lab products found in correlation
2 protocols using avanto mri machine
1
Knee MRI Protocol for dGEMRIC Assessment
2
Quantitative MRI Evaluation of Cartilage
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The dGEMRIC was performed as a T1 mapping based on 3-dimensional gradient-echo (3D-GRE) sequence with different flip angle combinations compared to standard IR sequence at 1.5T. We used a Siemens Avanto MRI machine (Siemens Healthcare GmbH, Erlangen, Germany) with similar methods to those used by Årøen et al. (2016). Protocols have been established by Burstein et al. (2001 (link)) and Tiderius et al. (2001 (link)). Our local protocol at Oslo University Hospital was modified based on the post-contrast imaging protocol of Burstein et al. (2001 (link)). The patients exercised on stairs for 15 min after contrast injection, then rested in 75 min, after which the post-contrast images were taken. The patients were in supine position until completion. The dGEMRIC value was read as T1(Gd). A T2 mapping for the index knee was also performed. The measurements were taken at 6 regions of interest (ROIs)—anteriorly, centrally, and posteriorly on the medial and lateral femoral condyles. An experienced MRI radiologist (HB), who was blinded regarding all other information related to the patients, evaluated the images. The dGEMRIC index could not be calculated for 8 regions in the injured knee in 5 patients and for 1 region in the uninjured knee in 1 patient, due to marked cartilage thinning.
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