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Cpz hydrochloride

Manufactured by Merck Group
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CPZ hydrochloride is a laboratory reagent used in various analytical techniques. It is a crystalline compound with a chemical formula of C17H19ClN2S·HCl. CPZ hydrochloride is commonly used as a standard or reference material in analytical procedures.

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Lab products found in correlation

Bacitracin, by Merck Group (1 mentions) Cytod, by Merck Group (1 mentions) Alexa fluor 488 c5 maleimide, by Thermo Fisher Scientific (1 mentions) Dynasore, by Merck Group (1 mentions) Filipin, by Merck Group (1 mentions) Recombinant mouse wnt3a, by R&D Systems (1 mentions) Epidermal growth factor (egf), by Thermo Fisher Scientific (1 mentions)

Close spelling variants of this product

Chlorpromazine hydrochloride (CPZ, Hydrochlorides

2 protocols using cpz hydrochloride

1

Lipid-based Nanoparticle Synthesis Protocol

Cited 1 time
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The following reagents were purchased: maleimide-PEG5000-carboxyl-NHS from NOF Corporation (Tokyo, Japan); 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) and cholesterol (chol) from Nippon Fine Chemicals (Osaka, Japan); Alexa Fluor® 488 C5-maleimide from Life Technologies (Carlsbad, CA, USA); CPZ hydrochloride, Nys, MβCD, Cyto D, Wort, and bacitracin from Sigma-Aldrich (St Louis, MO, USA); and rhodamine-PE lipid (Rho-PE) from Avanti Polar Lipids (Alabaster, AL, USA). The required 1,5-dioctadecyl L-glutamate (Glu2C18), PEG5000-Glu2C18, PEG5000-DSPE, GGLG, and maleimide-PEG5000-Glu2C18 were synthesized in our laboratory using previously published methods.17 (link)–19 (link)
Li T, & Takeoka S. (2014). Enhanced cellular uptake of maleimide-modified liposomes via thiol-mediated transport. International Journal of Nanomedicine, 9, 2849-2861.
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2

Modulating Cellular Signaling Pathways

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The sources and working concentrations of chemical and growth factors used in this study are: Dynasore (Sigma, D7693) at 80 μg/ml, and Ciliobrevin (Tocris 4529) at 100 μM, Filipin (Sigma, F4767) at 2 μg/ml, CPZ hydrochloride (Sigma, C8138) at 50 μg/ml, MβCD (Sigma, C4555) at 5 mM, EGF (Life Technologies, PMG8043) at 100 ng/ml, and recombinant mouse Wnt3a (R&D Systems, Minneapolis, MN) at 100 ng/ml.
Zhang X., Ren J., Wang J., Li S., Zou Q, & Gao N. (2018). Receptor-mediated endocytosis generates nanomechanical force reflective of ligand identity and cellular property. Journal of cellular physiology, 233(8), 5908-5919.
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