δ valerolactam

Manufactured by Merck Group

δ‐valerolactam is a heterocyclic organic compound used in various laboratory applications. It serves as a precursor for the synthesis of other chemical compounds. The core function of δ‐valerolactam is to facilitate specific chemical reactions and transformations in a controlled laboratory setting.

Automatically generated - may contain errors

Lab products found in correlation

β nicotinamide adenine dinucleotide nad, by Merck Group (1 mentions) Cadaverine, by Merck Group (1 mentions) Putrescine, by Fujifilm (1 mentions) 1 9 diaminononane, by Merck Group (1 mentions) L lysine, by Tokyo Chemical Industry (1 mentions) Cycloheximide (chx), by Merck Group (1 mentions) Glutarimide, by Merck Group (1 mentions) Glutaric anhydride, by Merck Group (1 mentions) Phthalimide, by Merck Group (1 mentions)

Spelling variants of this product

Valerolactam (2 citations)

2 protocols using δ valerolactam

Lysine Metabolism Biochemical Assays

Check if the same lab product or an alternative is used in the 5 most similar protocols

l‐Lysine and 5‐aminopentanoate were purchased from Tokyo Chemical Industry Co., Ltd. (https://www.tcichemicals.com); cadaverine, δ‐valerolactam, 1‐formylpyrrolidine, 1,9‐diaminononane and β‐nicotinamide adenine dinucleotide (NAD⁺) were obtained from Sigma‐Aldrich (http://www.sigmaaldrich.com); 5‐aminopentanal was acquired from Activate Scientific (https://shop.activate-scientific.com); [α‐¹⁵N]‐l‐Lysine and [ε‐¹⁵N]‐l‐lysine were purchased from Cambridge Isotope Laboratories Inc. (http://www.isotope.com); l‐ornithine, putrescine and all LC‐MS‐grade buffers used for LC‐MS were purchased from FUJIFILM Wako Pure Chemical Co. (http://www.wako-chem.co.jp).

Shimizu Y., Rai A., Okawa Y., Tomatsu H., Sato M., Kera K., Suzuki H., Saito K, & Yamazaki M. (2019). Metabolic diversification of nitrogen‐containing metabolites by the expression of a heterologous lysine decarboxylase gene in Arabidopsis. The Plant Journal, 100(3), 505-521.

+ Open protocol

+ Expand

Synthesis and Purification of Thalidomide Enantiomers

Check if the same lab product or an alternative is used in the 5 most similar protocols

Racemic thalidomide was purchased from Tocris Biosciences. (S)- and (R)-thalidomides and their deuterated (D-thalidomide) enantiomers were synthesized as previously described^{30 (link),57 (link)}. Enantiomeric purities were monitored by HPLC (DAICEL Chiralpak IA, 4.6 × 250 mm, MeOH = 100%, flow rate 1.0 ml/min, λ = 254 nm) and are summarized in Supplementary Table 1. Thalidomide and D-thalidomide enantiomers were dissolved in dimethylsulphoxide (DMSO) at room temperature to generate a 100 mM stock solution. Similarly, glutarimide, phthalimide, glutaric anhydride, δ-valerolactam and cycloheximide (Sigma Aldrich) were each dissolved in DMSO.

Mori T., Ito T., Liu S., Ando H., Sakamoto S., Yamaguchi Y., Tokunaga E., Shibata N., Handa H, & Hakoshima T. (2018). Structural basis of thalidomide enantiomer binding to cereblon. Scientific Reports, 8, 1294.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!