Magnetom Skyra 3T MRI system (Siemens, Erlangen, Germany) was used to perform blood oxygenation level-dependent (BOLD) fMRI. BOLD-weighted Echo Planar Imaging (EPI) parameters were as follows: repetition time (TR) = 2000 ms, echo time (TE) = 30 ms, slice thickness = 4 mm, field of view (FOV) = 210 mm, matrix size = 64 × 64, and flip angle = 90°. T1-weighted anatomical reference image parameters were as follows: 28 axial, 4-mm thick slices, an FOV of 210 mm, and spin echo images were obtained with a matrix size of 128 × 128. Total images were acquired parallel to the bicommissural line of the anterior commissure-posterior commissure.
Magnetom skyra 3t mri system
Manufactured by Siemens
Sourced in Germany
The Magnetom Skyra 3T MRI system is a magnetic resonance imaging (MRI) device produced by Siemens. It operates at a magnetic field strength of 3 Tesla, which provides high-quality images for medical diagnostic purposes.
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5 protocols using magnetom skyra 3t mri system
1
BOLD fMRI Acquisition for Neuroimaging
2
3T fMRI Protocol for Brain Imaging
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The Magnetom Skyra 3T MRI system (Siemens, Erlangen, Germany) and a standard head coil were used to perform blood oxygenation level-dependent (BOLD) fMRI. The BOLD-weighted Gradient-Echoplanar Imaging (EPI) parameters were acquired using the following parameters: repetition time = 2000 ms, echo time = 30 ms, field of view = 210 mm2, flip angle = 90°, matrix size = 64 × 64, and slice thickness = 4 mm. Anatomical T1-weighted gradient-echo images were obtained using the following parameters: repetition time = 250 ms, echo time = 2.86 ms, flip angle = 70°, a 1-mm slice thickness, a matrix size of 128 × 128, and a field of view of 210 mm. All images were acquired parallel to the anterior commissure-posterior commissure plane.
3
Prostate Cancer MRI Datasets
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In this study, we used transverse T2-weighted (T2W) MR images from two datasets: the publicly available PROSTATEx I training dataset (n = 204; 6 cases were excluded due to segmentations mismatching) [11 (link)], and an in-house collected multiparametric 3 T MRI dataset (n = 233).
The in-house collected dataset was obtained from St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway between March 2015 and December 2017 as part of a previous prospective study [12 (link)]. It consists of mpMR images from 233 patients (median age = 65; range: 44–76 years) who were examined due to suspicion of prostate cancer, via the Norwegian standardized care pathway, in which patients with elevated PSA and/or abnormal digital rectal exam results are referred for an initial mpMRI scan to identify suspicious cancerous tissue. T2W imaging was performed on a Magnetom Skyra 3 T MRI system (Siemens Healthineers, Erlangen, Germany) with a turbo spin-echo sequence (repetition time/echo time = 4450–9520/101–108 ms, 320 × 320–384 × 384 matrix size, 26–64 slices, 3–3.5 mm slice thickness and 0.5 × 0.5–0.6 × 0.6 mm2 in-plane resolution).
The in-house collected dataset was obtained from St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway between March 2015 and December 2017 as part of a previous prospective study [12 (link)]. It consists of mpMR images from 233 patients (median age = 65; range: 44–76 years) who were examined due to suspicion of prostate cancer, via the Norwegian standardized care pathway, in which patients with elevated PSA and/or abnormal digital rectal exam results are referred for an initial mpMRI scan to identify suspicious cancerous tissue. T2W imaging was performed on a Magnetom Skyra 3 T MRI system (Siemens Healthineers, Erlangen, Germany) with a turbo spin-echo sequence (repetition time/echo time = 4450–9520/101–108 ms, 320 × 320–384 × 384 matrix size, 26–64 slices, 3–3.5 mm slice thickness and 0.5 × 0.5–0.6 × 0.6 mm2 in-plane resolution).
4
MRI Evaluation of Embolization Outcomes
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All patients underwent MRI using the Siemens MAG-NETOM Avanto 1.5-T MRI system (Siemens Healthineers) (through March 2014) or the Siemens MAGNE-TOM Skyra 3-T MRI system (beginning in April 2014). MRI scans, including DWI and T2*WI pretreatment and 24-36 hours posttreatment, were routinely obtained in both groups. Patients were scheduled for a 6-month followup. Three patients whose follow-up MRI studies could not be obtained were excluded. The pre-and postembolization MRI and 6-month follow-up MRI studies for each patient were independently scored by 2 reviewers (R.N. and Y.K.) for the presence of procedure-related DWI and T2*WI lesions, and the absolute values of the number of DWI and T2*WI lesions on each MRI study were noted (Figs. 1 and2). On each follow-up MRI study, only new T2*WI lesions that were not present on the preprocedural MRI study were scored.
5
Multimodal Brain Imaging of Healthy Adults
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Twenty-two healthy subjects were included in the study (age range 19-40 years, 12 females). MP2RAGE images were acquired from all subjects, and DTI images in 10 subjects. All subjects were scanned on a Siemens Magnetom Skyra 3T MRI system with a 32-channel head coil. MP2RAGE parameters were acquired with TR=5s, TI 1 =0.7s, TI 2 =2.5s, α 1 =4°, α 2 =5°, a 3D sequence imaged at isotropic 1 mm 3 resolution (acquisition matrix: 240x256, 176 sagittal slices), Turbo factor of 176 as defined by Marques et al. [13] . DTI was acquired with 32 directions, 5 B0 acquisitions, TR=10.9s, TE=0.079, TI= 2.1s, imaged at isotropic 2.3 mm 3 resolution (acquisition matrix: 96x96, 38 axial slices), and inversion recovery based CSF suppression to reduce partial volume effects. Fig. 1 provides an overview of the methods and comparisons.
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