Bilateral MRI was performed using a 1.5 T or 3.0 T (Avanto; Siemens Medical Solutions, Erlangen, Germany, Skyra; Siemens Medical Solutions, Erlangen, Germany, Ingenia; Philips, Best, The Netherlands) MR scanner and a dedicated 18-channel phased-array breast coil (Siemens Medical Solutions) with the patient in a prone position. The imaging protocol included a T2-weighted short tau inversion recovery turbo spin-echo pulse sequence (repetition time [TR]/echo time [TE], 1300/131; matrix size, 384 × 384; field of view [FOV], 340 × 340 mm2; slice thickness, 1.5 mm for the 1.5 T scanner; TR/TE, 1100/131; matrix size, 256 × 416; FOV, 341 × 210 mm2; section thickness,1.5 mm for the 3.0 T scanner) and a dynamic contrast material-enhanced fat-saturated axial three-dimensional T1-weighted fast low-angle shot sequence (TR/TE, 5.0/2.4; matrix size, 384 × 384; FOV, 340 × 340 mm2; section thickness, 0.9 mm for the 1.5 T scanner; TR/TE, 5.6/2.5; matrix size, 384 × 384; FOV, 360 × 360 mm2; section thickness, 0.9 mm for the 3.0 T scanner), consisting of unenhanced and five contrast-enhanced acquisitions. Contrast material (0.2 mL/kg gadoterate meglumine; UNIRAY®; Dongkook Pharmaceutical Co., Ltd., Seoul, Korea) was power-injected (Spectris; Medrad, Pittsburgh, PA, USA) at a flow rate of 1 mL/s, followed by a 20 mL saline flush.
Spectris
Manufactured by Bayer
Sourced in United States
The Spectris is a versatile lab equipment designed for spectroscopic analysis. It is capable of measuring the absorption, emission, or scattering of light by a sample. The core function of the Spectris is to provide accurate and reliable data on the properties of various materials and substances.
Automatically generated - may contain errors
Lab products found in correlation
Magnevist, by Bayer (4 mentions)
Magnetom aera, by Siemens (3 mentions)
Magnetom trio, by Siemens (3 mentions)
Gadovist, by Bayer (3 mentions)
Magnetom sonata, by Siemens (2 mentions)
Magnetom symphony, by Siemens (2 mentions)
Dotarem, by Guerbet (2 mentions)
Ingenia, by Siemens (1 mentions)
Dedicated 18 channel phased array breast coil, by Siemens (1 mentions)
Magnescope, by Guerbet (1 mentions)
Signa excite hdxt, by GE Healthcare (1 mentions)
Discovery mr750, by GE Healthcare (1 mentions)
Omniscan, by GE Healthcare (1 mentions)
Magnetom avanto, by Siemens (1 mentions)
Signa excite, by GE Healthcare (1 mentions)
Signa hdxt, by GE Healthcare (1 mentions)
Sense nv coil, by Philips (1 mentions)
Achieva, by Philips (1 mentions)
Intera achieva, by Philips (1 mentions)
Omniscan, by Takeda Pharmaceuticals (1 mentions)
20 protocols using spectris
1
Bilateral MRI Breast Imaging Protocol
2
Contrast-Enhanced MRI Protocol for Abdominal Imaging
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MRI was performed with a 1.5 T MR scanner (Magnetom Aera; Siemens Medical Systems). Patients were positioned in a supine position with the head oriented toward the magnet. One abdominal surface flex coil with 18 channels covered the chest area. Gadopentetate dimeglumine (Magnevist; Bayer Schering Pharma AG) was injected into the right antecubital vein via a 22-gauge needle using a power injector (Spectris; MedRad). The MRPA sequence was initiated by using the bolus tracking technique, with 0.1 mmol/kg contrast material injected at 2.5 ml/sec and followed by a 15-ml saline flush at 2.5 ml/sec.
MR scanning was performed in a fixed order with the following sequences: i) True FISP in coronal and axial orientations without contrast material and no need for breath-hold; ii) contrast-enhanced MRPA scanned by subtraction of 3D-FLASH sequences from prior to and after administration of the contrast agent in coronal orientation, with 3 times for breath-hold, including one time for pre-contrast and the other two times for post-contrast for 18 sec each time; and iii) T1-weighted fat-suppressed VIBE in coronal and axial orientations with 3 times for breath-hold, 18 sec each time. The detailed parameters are listed inTable I .
MR scanning was performed in a fixed order with the following sequences: i) True FISP in coronal and axial orientations without contrast material and no need for breath-hold; ii) contrast-enhanced MRPA scanned by subtraction of 3D-FLASH sequences from prior to and after administration of the contrast agent in coronal orientation, with 3 times for breath-hold, including one time for pre-contrast and the other two times for post-contrast for 18 sec each time; and iii) T1-weighted fat-suppressed VIBE in coronal and axial orientations with 3 times for breath-hold, 18 sec each time. The detailed parameters are listed in
3
Multimodal MRI Techniques for Brain Tumor
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All MRI examinations were performed within 7 days before surgery. The precontrast sequence consisted of axial T1-weighted image (T1WI), T2-weighted image (T2WI), DWI, and fluid-attenuated inversion recovery (FLAIR). Once the precontrast imaging was completed, 0.2 mL/kg gadolinium (Gd)-based MR contrast agent (gadoterate meglumine, MAGNESCOPE; Guerbet, Tokyo, Japan) at a rate of 3 mL/s was administered without preload by an MRI-compatible power injector (Spectris; Medrad, Pittsburgh, PA, USA) followed by a 30-mL bolus of saline flush. Postcontrast 3D T1WIs were obtained immediately after DSC-PWI. All patients were scanned on a 3T scanner (Signa Excite HDxt; GE Healthcare, Milwaukee, USA) with an 8-channel head coil. A DWI using spin echo (SE) echo-planar imaging (EPI) sequence was performed with TR/TE = 6,000/90 ms, FA = 90°, slice thickness = 5 mm, b = 0, 1,000, FOV = 240 mm, matrix = 128 × 128, 20 slices per 1 mm gap. A DSC-PWI using the gradient-echo EPI (GRE-EPI) sequence was performed with TR/TE = 2,000/21 ms, FA = 60°, matrix 96 × 128; FOV, 220 mm; slice thickness = 5 mm, 20 slices per 1 mm gap.
4
Dynamic Breast MRI Protocol
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All imaging was performed on 1.5 Tesla units (Magnetom Symphony and Magnetom Sonata, Siemens Medical Solutions, Erlangen, Germany). Dedicated vendor-supplied four-channel bilateral breast coils were used. The MRI-protocol adhered to international recommendations [22 (link),23 ] and employed a dynamic sequence with 1-minute temporal resolution performed once before and seven times after automated injection (3 ml per second, Spectris, Medrad, Pittsburgh, USA) of 0.1 mmol/kg Gd-DTPA (Magnevist, Bayer Health Care, Leverkusen, Germany) into a cubital vein. Axial views of patients in prone positions were obtained. Subtractions were calculated by subtracting precontrast from postcontrast sequences.
5
Dynamic Contrast-Enhanced MRI of Thyroid Tumors
6
Contrast-Enhanced Liver MRI Protocol
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Liver imaging was performed with contrast enhanced MRI using 3-Tesla scanners (Skyra® or Magnetom Trio®, Siemens). Study protocols included: T1w FLASH 2d (in- and opposed phase), T2w HASTE, DWI, contrast enhanced dynamic 3d VIBE sequences [start delay after contrast bolus: 0 s (native), 20 s (arterial), 45 s (portal-venous), and 90 s (equilibrium-Phase)], and a late 2d FLASH phase. Gadolinium-DTPA (Magnevist®, Bayer Schering Pharma AG), 0.1 mmol/kg body weight, 2 ml/s, was administered by bolus injection (Spectris®, Medrad) for contrast. Image analysis was carried out independently by two investigators experienced in cross sectional liver imaging. This analysis was followed by a consensus reading to obtain the final diagnosis.
7
Multiparametric MRI Protocol for Breast Cancer
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For generating the precontrast T1 (ie, T10) maps, T1w images were acquired using the fast 3D T1w spoiled gradient recalled echo (SPGR) sequence with multiple FAs of 5°, 15°, and 30°. The DCE data acquisition scheme is shown in Figure 4B . Other acquisition MR parameters were as follows: TR/TE = 5.6 / 2.3 milliseconds, acquisition matrix = 231 × 116 reconstructed to matrix = 256 × 256 by zero-filling, FOV = 30–35 cm, slice thickness = 6 mm, slice spacing = 6 mm, and NS = 10–12. T1w dynamic series data were acquired for 20 phases with FA = 15° and other MR parameters, as mentioned above. After acquiring 3–4 precontrast images, a bolus of 0.1 mmol/kg Gd-based CA, used in clinical practice, was delivered through an antecubital vein catheter at 2 cc/s, followed by a 20-mL saline flush using an MR-compatible programmable power injector (Spectris; Medrad, Indianola, PA). DCE-MRI data were acquired with a series of multiple breath-holds. In the clinical setting, patients were requested by the technologist to hold their breath for ∼15 seconds followed by a ∼5-second break; the process was repeated multiple times for ≤5 minutes.
8
Multiparametric Breast MRI Protocol
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MRI was performed on a 1.5 T MR scanner (Magnetom Avanto, Siemens Medical Solutions) with an 8-channel phased-array breast coil (Siemens Medical Solutions). The patients were placed in the prone position with a body parallel to the shoulders, and both breasts were naturally suspended in the coil. The sequences included axial T2-weighted imaging (T2WI), axial T1-weighted imaging (T1WI), axial diffusion-weighted imaging (DWI) with readout segmented echo planar imaging, followed by axial dynamic contrast-enhanced imaging (DCE), axial and coronal delayed contrast-enhanced T1WI (T1 + C). Two dynamic phases of DCE acquisition (40 phases with a temporal resolution of 8 s) were initially performed. And then, all patients underwent intravenous bolus injection of Gd-DTPA-BMA (Omniscan, GE Healthcare; dose = 0.1 mmol/kg body weight; flow rate = 3.5 ml/s) through a high-pressure contrast agent injector (Spectris, Medrad). The T1 + C images were obtained immediately after the DCE imaging was finished. The detailed acquisition parameters are shown in Table 1
9
MRI Imaging Protocol for Brain Analysis
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For each patient, the pretreated MR imaging was performed using 1.5 T (Signa HDxt; GE Medical Systems, Milwaukee, WI) and 3.0 T (Verio; Siemens Medical Solutions, Erlangen, Germany or Biography; Siemens Medical Solutions, Erlangen, Germany or Discovery; GE Medical Systems, Milwaukee, WI or Signa Excite; GE Medical Systems, Milwaukee, WI) scanners which were randomly distributed. The analyzed brain imaging sequences on various MR scanners are presented in Supplementary Table 4 . Those sequences included FLAIR, DSC PWI with gadobutrol (Gadovist, Bayer Healthcare, Berlin, Germany), and subsequent contrast-enhanced spin-echo T1 weighted image. For DSC PWI, a single-shot gradient-echo EPI sequences was used during intravenous injection of the contrast agent. For each section, 60 images were obtained at intervals equal to the repetition time. After four to five time points, a bolus of gadobutrol at a dose of 0.1 mmoL/kg of body weight and a rate of 4 ml/sec was injected with an MR compatible power injector (Spectris; Medrad, Pittsburgh, PA, USA). The bolus of the contrast material was followed by a 30 mL bolus of saline, which was administered at the same injection rate.
10
Dynamic Susceptibility Contrast MRI Protocol
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The Dynamic susceptibility contrast MRI (DSC-MRI) protocol consisted of a series of 80 whole-brain images using a single-shot free induction decay (FID)-EPI sequence. DSC parameters were in detail: field of view = 224 × 224 mm; voxel size = 1.8 × 1.8 × 5 mm3; slices = 21; acceleration factor = 2; TR/TE = 1,390 /29 ms; flip angle = 60°; time of acquisition = 1:54 min; 5 mL Gadovist (Gadobutrol, 1 mol/L; Bayer Schering Pharma AG, Berlin, Germany) followed by a 25 mL saline flush, injected using a power injector (Spectris, Medrad, Warrendale PA, United States) at a rate of 5 mL/s. Acquisition parameters are in line with the recommendations by the Acute Stroke Research Imaging Roadmap (27 (link)).
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