The largest database of trusted experimental protocols

20 protocols using spectris

1

Bilateral MRI Breast Imaging Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Bilateral MRI was performed using a 1.5 T or 3.0 T (Avanto; Siemens Medical Solutions, Erlangen, Germany, Skyra; Siemens Medical Solutions, Erlangen, Germany, Ingenia; Philips, Best, The Netherlands) MR scanner and a dedicated 18-channel phased-array breast coil (Siemens Medical Solutions) with the patient in a prone position. The imaging protocol included a T2-weighted short tau inversion recovery turbo spin-echo pulse sequence (repetition time [TR]/echo time [TE], 1300/131; matrix size, 384 × 384; field of view [FOV], 340 × 340 mm2; slice thickness, 1.5 mm for the 1.5 T scanner; TR/TE, 1100/131; matrix size, 256 × 416; FOV, 341 × 210 mm2; section thickness,1.5 mm for the 3.0 T scanner) and a dynamic contrast material-enhanced fat-saturated axial three-dimensional T1-weighted fast low-angle shot sequence (TR/TE, 5.0/2.4; matrix size, 384 × 384; FOV, 340 × 340 mm2; section thickness, 0.9 mm for the 1.5 T scanner; TR/TE, 5.6/2.5; matrix size, 384 × 384; FOV, 360 × 360 mm2; section thickness, 0.9 mm for the 3.0 T scanner), consisting of unenhanced and five contrast-enhanced acquisitions. Contrast material (0.2 mL/kg gadoterate meglumine; UNIRAY®; Dongkook Pharmaceutical Co., Ltd., Seoul, Korea) was power-injected (Spectris; Medrad, Pittsburgh, PA, USA) at a flow rate of 1 mL/s, followed by a 20 mL saline flush.
+ Open protocol
+ Expand
2

Contrast-Enhanced MRI Protocol for Abdominal Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols
MRI was performed with a 1.5 T MR scanner (Magnetom Aera; Siemens Medical Systems). Patients were positioned in a supine position with the head oriented toward the magnet. One abdominal surface flex coil with 18 channels covered the chest area. Gadopentetate dimeglumine (Magnevist; Bayer Schering Pharma AG) was injected into the right antecubital vein via a 22-gauge needle using a power injector (Spectris; MedRad). The MRPA sequence was initiated by using the bolus tracking technique, with 0.1 mmol/kg contrast material injected at 2.5 ml/sec and followed by a 15-ml saline flush at 2.5 ml/sec.
MR scanning was performed in a fixed order with the following sequences: i) True FISP in coronal and axial orientations without contrast material and no need for breath-hold; ii) contrast-enhanced MRPA scanned by subtraction of 3D-FLASH sequences from prior to and after administration of the contrast agent in coronal orientation, with 3 times for breath-hold, including one time for pre-contrast and the other two times for post-contrast for 18 sec each time; and iii) T1-weighted fat-suppressed VIBE in coronal and axial orientations with 3 times for breath-hold, 18 sec each time. The detailed parameters are listed in Table I.
+ Open protocol
+ Expand
3

Multimodal MRI Techniques for Brain Tumor

Check if the same lab product or an alternative is used in the 5 most similar protocols
All MRI examinations were performed within 7 days before surgery. The precontrast sequence consisted of axial T1-weighted image (T1WI), T2-weighted image (T2WI), DWI, and fluid-attenuated inversion recovery (FLAIR). Once the precontrast imaging was completed, 0.2 mL/kg gadolinium (Gd)-based MR contrast agent (gadoterate meglumine, MAGNESCOPE; Guerbet, Tokyo, Japan) at a rate of 3 mL/s was administered without preload by an MRI-compatible power injector (Spectris; Medrad, Pittsburgh, PA, USA) followed by a 30-mL bolus of saline flush. Postcontrast 3D T1WIs were obtained immediately after DSC-PWI. All patients were scanned on a 3T scanner (Signa Excite HDxt; GE Healthcare, Milwaukee, USA) with an 8-channel head coil. A DWI using spin echo (SE) echo-planar imaging (EPI) sequence was performed with TR/TE = 6,000/90 ms, FA = 90°, slice thickness = 5 mm, b = 0, 1,000, FOV = 240 mm, matrix = 128 × 128, 20 slices per 1 mm gap. A DSC-PWI using the gradient-echo EPI (GRE-EPI) sequence was performed with TR/TE = 2,000/21 ms, FA = 60°, matrix 96 × 128; FOV, 220 mm; slice thickness = 5 mm, 20 slices per 1 mm gap.
+ Open protocol
+ Expand
4

Dynamic Breast MRI Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
All imaging was performed on 1.5 Tesla units (Magnetom Symphony and Magnetom Sonata, Siemens Medical Solutions, Erlangen, Germany). Dedicated vendor-supplied four-channel bilateral breast coils were used. The MRI-protocol adhered to international recommendations [22 (link),23 ] and employed a dynamic sequence with 1-minute temporal resolution performed once before and seven times after automated injection (3 ml per second, Spectris, Medrad, Pittsburgh, USA) of 0.1 mmol/kg Gd-DTPA (Magnevist, Bayer Health Care, Leverkusen, Germany) into a cubital vein. Axial views of patients in prone positions were obtained. Subtractions were calculated by subtracting precontrast from postcontrast sequences.
+ Open protocol
+ Expand
5

Dynamic Contrast-Enhanced MRI of Thyroid Tumors

Check if the same lab product or an alternative is used in the 5 most similar protocols
MRI scans were performed on a 3.0 T MR scanner (Discovery MR 750,
GE Healthcare, Milwaukee, WI) with a neurovascular phased-array coil before
surgery. Preceding the DCE-MRI, anatomical scans, including T1w and
T2-weighted (T2w) MRI scans covering the entire
thyroid gland, were performed. DCE-MRI images were acquired using a 3D
T1w SPGR pulse sequence with a flip angle of 15° and other
imaging parameters as follows: repetition time (TR)/echo time (TE) = 5.7/1.7 ms,
acquisition matrix=256×128 that was zero-filled to 256×256 during
image reconstruction, field of view = 20–24 cm, slice thickness=5 mm, and
6–8 slices covering the tumor region, which yielded images with a
temporal resolution ranging from 4.4 to 5.8 s. A total of 50 dynamic volumes
were acquired in ~ 5 minutes. A bolus of 0.1 mmol/kg Gd-based CA, used in
clinical practice, was delivered through an antecubital vein catheter at 2 cc/s,
followed by a 20-ml saline flush using an MR-compatible programmable power
injector (Spectris; Medrad, Indianola, PA, USA). Prior to the dynamic imaging
acquisitions, precontrast T1w images were acquired for T1mapping using the same 3D T1w SPGR sequence parameters with multiple
flip angles of 5°, 15°, and 30°.
+ Open protocol
+ Expand
6

Contrast-Enhanced Liver MRI Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Liver imaging was performed with contrast enhanced MRI using 3-Tesla scanners (Skyra® or Magnetom Trio®, Siemens). Study protocols included: T1w FLASH 2d (in- and opposed phase), T2w HASTE, DWI, contrast enhanced dynamic 3d VIBE sequences [start delay after contrast bolus: 0 s (native), 20 s (arterial), 45 s (portal-venous), and 90 s (equilibrium-Phase)], and a late 2d FLASH phase. Gadolinium-DTPA (Magnevist®, Bayer Schering Pharma AG), 0.1 mmol/kg body weight, 2 ml/s, was administered by bolus injection (Spectris®, Medrad) for contrast. Image analysis was carried out independently by two investigators experienced in cross sectional liver imaging. This analysis was followed by a consensus reading to obtain the final diagnosis.
+ Open protocol
+ Expand
7

Multiparametric MRI Protocol for Breast Cancer

Check if the same lab product or an alternative is used in the 5 most similar protocols
For generating the precontrast T1 (ie, T10) maps, T1w images were acquired using the fast 3D T1w spoiled gradient recalled echo (SPGR) sequence with multiple FAs of 5°, 15°, and 30°. The DCE data acquisition scheme is shown in Figure 4B. Other acquisition MR parameters were as follows: TR/TE = 5.6 / 2.3 milliseconds, acquisition matrix = 231 × 116 reconstructed to matrix = 256 × 256 by zero-filling, FOV = 30–35 cm, slice thickness = 6 mm, slice spacing = 6 mm, and NS = 10–12. T1w dynamic series data were acquired for 20 phases with FA = 15° and other MR parameters, as mentioned above. After acquiring 3–4 precontrast images, a bolus of 0.1 mmol/kg Gd-based CA, used in clinical practice, was delivered through an antecubital vein catheter at 2 cc/s, followed by a 20-mL saline flush using an MR-compatible programmable power injector (Spectris; Medrad, Indianola, PA). DCE-MRI data were acquired with a series of multiple breath-holds. In the clinical setting, patients were requested by the technologist to hold their breath for ∼15 seconds followed by a ∼5-second break; the process was repeated multiple times for ≤5 minutes.
+ Open protocol
+ Expand
8

Multiparametric Breast MRI Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
MRI was performed on a 1.5 T MR scanner (Magnetom Avanto, Siemens Medical Solutions) with an 8-channel phased-array breast coil (Siemens Medical Solutions). The patients were placed in the prone position with a body parallel to the shoulders, and both breasts were naturally suspended in the coil. The sequences included axial T2-weighted imaging (T2WI), axial T1-weighted imaging (T1WI), axial diffusion-weighted imaging (DWI) with readout segmented echo planar imaging, followed by axial dynamic contrast-enhanced imaging (DCE), axial and coronal delayed contrast-enhanced T1WI (T1 + C). Two dynamic phases of DCE acquisition (40 phases with a temporal resolution of 8 s) were initially performed. And then, all patients underwent intravenous bolus injection of Gd-DTPA-BMA (Omniscan, GE Healthcare; dose = 0.1 mmol/kg body weight; flow rate = 3.5 ml/s) through a high-pressure contrast agent injector (Spectris, Medrad). The T1 + C images were obtained immediately after the DCE imaging was finished. The detailed acquisition parameters are shown in Table 1.
+ Open protocol
+ Expand
9

MRI Imaging Protocol for Brain Analysis

Check if the same lab product or an alternative is used in the 5 most similar protocols
For each patient, the pretreated MR imaging was performed using 1.5 T (Signa HDxt; GE Medical Systems, Milwaukee, WI) and 3.0 T (Verio; Siemens Medical Solutions, Erlangen, Germany or Biography; Siemens Medical Solutions, Erlangen, Germany or Discovery; GE Medical Systems, Milwaukee, WI or Signa Excite; GE Medical Systems, Milwaukee, WI) scanners which were randomly distributed. The analyzed brain imaging sequences on various MR scanners are presented in Supplementary Table 4. Those sequences included FLAIR, DSC PWI with gadobutrol (Gadovist, Bayer Healthcare, Berlin, Germany), and subsequent contrast-enhanced spin-echo T1 weighted image. For DSC PWI, a single-shot gradient-echo EPI sequences was used during intravenous injection of the contrast agent. For each section, 60 images were obtained at intervals equal to the repetition time. After four to five time points, a bolus of gadobutrol at a dose of 0.1 mmoL/kg of body weight and a rate of 4 ml/sec was injected with an MR compatible power injector (Spectris; Medrad, Pittsburgh, PA, USA). The bolus of the contrast material was followed by a 30 mL bolus of saline, which was administered at the same injection rate.
+ Open protocol
+ Expand
10

Dynamic Susceptibility Contrast MRI Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
The Dynamic susceptibility contrast MRI (DSC-MRI) protocol consisted of a series of 80 whole-brain images using a single-shot free induction decay (FID)-EPI sequence. DSC parameters were in detail: field of view = 224 × 224 mm; voxel size = 1.8 × 1.8 × 5 mm3; slices = 21; acceleration factor = 2; TR/TE = 1,390 /29 ms; flip angle = 60°; time of acquisition = 1:54 min; 5 mL Gadovist (Gadobutrol, 1 mol/L; Bayer Schering Pharma AG, Berlin, Germany) followed by a 25 mL saline flush, injected using a power injector (Spectris, Medrad, Warrendale PA, United States) at a rate of 5 mL/s. Acquisition parameters are in line with the recommendations by the Acute Stroke Research Imaging Roadmap (27 (link)).
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!