C57/BL6 mice or Balb/c mice were immunized with TK− HSV-2 virus. Five to eight weeks later, these mice were injected i.v. (tail vain) with 300 µg of anti-CD4 (GK1.5; BioXCell) or anti-IFN-γ (XMG1.2; BioXCell) Ab at days −4, −1, 2 and 4 after HSV-2 challenge. In vivo depletion for CD4 was confirmed by FACS analysis of the cell suspension from spleen. For the neutralization of α4-integrin, purified anti-mouse α4 integrin/CD49d (PS/2; SouthernBiotech) was given a tail vain injection of 300 µg Ab at days 2 and 4 after challenge.
Anti mouse α4 integrin cd49d ps 2
Manufactured by Southern Biotech
The Anti-mouse α4 integrin/CD49d (PS/2) is a laboratory product used for research purposes. It functions as an antibody that binds to the α4 integrin, also known as CD49d, on the surface of mouse cells.
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Lab products found in correlation
2 protocols using anti mouse α4 integrin cd49d ps 2
1
Studying HSV-2 Immunity in Mice
2
Studying HSV-2 Immunity in Mice
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C57/BL6 mice or Balb/c mice were immunized with TK− HSV-2 virus. Five to eight weeks later, these mice were injected i.v. (tail vain) with 300 µg of anti-CD4 (GK1.5; BioXCell) or anti-IFN-γ (XMG1.2; BioXCell) Ab at days −4, −1, 2 and 4 after HSV-2 challenge. In vivo depletion for CD4 was confirmed by FACS analysis of the cell suspension from spleen. For the neutralization of α4-integrin, purified anti-mouse α4 integrin/CD49d (PS/2; SouthernBiotech) was given a tail vain injection of 300 µg Ab at days 2 and 4 after challenge.
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