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Quinine hydrochloride qhcl

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Quinine hydrochloride (QHCl) is a chemical compound used as a laboratory reagent. It is a crystalline solid that is soluble in water and other polar solvents. QHCl is commonly used in various scientific applications, such as analytical chemistry and biochemistry, as a standard or reference material.

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Quinine (87 citations) Quinine hydrochloride (26 citations) Hydrochlorides (2 citations)

2 protocols using quinine hydrochloride qhcl

1

Taste Stimulus Preparation Protocol

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Taste stimuli were prepared daily in water and consisted of EtOH (Decon Labs) diluted from 200-proof stock solution, quinine hydrochloride (QHCl; Sigma Aldrich), and sucrose (Wegmans). All stimuli were presented at room temperature.
Lazarus H.M., Belanger R., Candoni A., Aoun M., Jurewicz R, & Marks L. (1999). Intravenous Penciclovir for Treatment of Herpes Simplex Infections in Immunocompromised Patients: Results of a Multicenter, Acyclovir-Controlled Trial. Antimicrobial Agents and Chemotherapy, 43(5), 1192-1197.
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2

Bitter Compound and Anti-Malarial Dosage Effects

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The synthetic bitter compound denatonium benzoate (DB) and the former anti-malarial drug which is now used as a food additive, quinine hydrochloride (QHCl) were purchased from Sigma-Aldrich (St Louis, MO, USA) and Fagron (Rotterdam, The Netherlands) respectively. Both solutions were prepared in Milli-Q water and the dose was determined based on similar studies (12, 13, 25) . Product administration concentrations were 1 µmol/kg body weight, 10 µmol/kg body weight and 0.1 ml/kg body weight for DB, QHCl and placebo (PLC) (water) respectively.
Verbeure W., Deloose E., Tóth J., Rehfeld J.F., Van Oudenhove L., Depoortere I, & Tack J. (2021). The endocrine effects of bitter tastant administration in the gastrointestinal system: intragastric versus intraduodenal administration. American journal of physiology. Endocrinology and metabolism, 321(1).
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