Gyroscan intera 1.5 t cv nova dual scanner

Adipose tissue depot masses were measured with MRI. MRI scans were performed using Philips Gyroscan Intera 1.5 T CV Nova Dual scanner (Philips Medical Systems). Abdominal area axial T1 weighted dual fast field echo images (echo time 2.3 and 4.7 ms, repetition time 120 ms, slice thickness 10 mm without gap) were obtained. To measure different adipose tissue masses, the images were analyzed using SliceOmatic software version 4.3 (http://www.tomovision.com/products/sliceomatic.html). To obtain the mass, the pixel surface area was multiplied with the slice thickness and the density of adipose tissue, 0.9196 kg/l (1 (link)).

Clinical screening and anthropometric and biochemical measurements were performed as previously described [26 (link)]. Blood pressure was measured with OMRON 711 automatic blood pressure monitor (Omron Corporate, Kyoto, Japan). Before the measurements, subjects were sitting for >10 min in a quiet room. A study nurse then assessed each subject twice for blood pressure measurements within a five-minute interval, and the average value was considered for the analysis. Subjects then underwent whole-body magnetic resonance imaging (MRI) with either a Philips Gyroscan Intera 1.5 T CV Nova Dual scanner (Philips, Amsterdam, The Netherlands) or with a Siemens Magnetom Skyra fit 3T MRI scanner (Siemens Medical Solutions, Erlangen, Germany). MRI acquisition was performed with axial T1-weighted dual fast field echo images (echo time (TE) 2.3 and 4.6 ms, repetition time (TR) 120 ms, slice thickness 10 mm without gap, matrix 256 × 256) or with T1-weighted 3D VIBE two-point DIXON sequence in breath-hold mode (TE 1.2 and 2.5 ms, TR 4.0 ms, slice thickness 2 mm with 0.4 mm gap, matrix 182 × 224). Subjects were scanned from head to knee or to ankle in a supine position. Total scan duration was 20 min. In obese patients, the imaging studies were performed before the standard four-week very-low calorie diet that preceded surgery.