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4 protocols using bpn 3j

1

Mouse Strain Characterization for Immunology

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A total of 23 mouse strains (129X1/SvJ, A/J, AKR/J, B10.S-H2s/SgMcdJ (B10.S), BALB/cJ, BPL/1J, BPN/3J, C3H/HeJ, C57BL/6J, C57BL/10J, CBA/J, CZECHII/EiJ, DBA/1J, DBA/2J, FVB/NJ, JF1/MsJ, MOLF/EiJ, MRL/MpJ, NOD/ShiLtJ, NU/J, PWD/PhJ, PWK/PhJ, SJL/J and SWR/J were purchased from the Jackson Laboratory (Bar Harbor, ME). All mice, including B10.S-HisthSJL and B10.S-HisthSJL ISRC lines, were generated and maintained under specific pathogen-free conditions in the vivarium of the Given Medical Building at the University of Vermont according to National Institutes of Health guidelines. All animal studies were approved by the Institutional Animal Care and Use Committee of the University of Vermont.
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2

Hypertension Rat and Mouse Models

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Sprague-Dawley, Wistar-Kyoto, and Spontaneously Hypertensive Rats (SHRs) were purchased from Charles River, Wilmington, MA. C57BL/6 mice, as well as genetically hypertensive mice (BPH/2J) and their matched normotensive mice (BPN/3J), were obtained from the Jackson Laboratory. All experimental procedures done with animals were approved by the Institutional Care and Use Committee at Albert Einstein College of Medicine in accordance with the “Guide for the Care and Use of Laboratory Animals” published by the National Institute of Health.
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3

Hypertensive and Normotensive Mouse Husbandry

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Hypertensive (BPH/2J, strain #:003005) and normotensive (BPN/3J, strain #003004) mice19–21 (link) were procured from Jackson Laboratory and bred in-house in specific pathogen-free condition at the University of Toledo College of Medicine and Life Sciences, Department of Laboratory Animal Resources. Mice were housed in cages (n = 5 mice/cage) containing corn cob bedding (Bed-O-Cob; The Andersons Co.) and nestlets (Cat #CABFM00088; Ancare). The cages were housed at 23°C under a 12/12-h light/dark phase cycle and fed a grain-based laboratory chow diet (LabDiet 5001), ad libitum. The institutional animal care and use committee (IACUC) at the University of Toledo approved all the mouse experiments.
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4

Comparing BPH/2j and BPN/3J Mice

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This experimental animal study was submitted to the approval of the Animal Experiment Committee of Forsyth Institute, no. 14/004. BPH/2j and its normal control, BPN/3J, mouse strains were purchased from Jackson Laboratory, Bar Harbor, Maine. The mice were maintained in accordance with the guidelines of the Animal Experiment Committee of Forsyth Institute.
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