Ie33 system

Manufactured by Philips

Sourced in United States, Netherlands, Germany

The IE33 system is a diagnostic imaging device developed by Philips. It is designed to capture and display high-quality ultrasound images for medical professionals. The core function of the IE33 system is to provide detailed visualization of internal structures and organs, enabling healthcare professionals to make informed clinical decisions.

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Lab products found in correlation

S5 1 transducer, by Philips (10 mentions) S5 1 transthoracic probe, by Philips (7 mentions) Syngo dynamics workstation, by Siemens (4 mentions) Syngo dynamics, by Siemens (3 mentions) X5 1 probe, by Philips (3 mentions) Xbp 1000, by Kent Scientific (2 mentions) Au1000, by Olympus (1 mentions) Ge vivid 7 system, by GE Healthcare (1 mentions) S5 1 probe, by Philips (1 mentions) Dotarem, by Guerbet (1 mentions) Vevo2100 high resolution ultrasound system, by Fujifilm (1 mentions) 40 mhz transducer, by Fujifilm (1 mentions) Cardiac performance analysis v 3, by Tomtec (1 mentions) Catheter, by Millar (1 mentions) 1.4f micromanometer tipped catheter, by Millar (1 mentions) Intellispace cardiovascular, by Philips (1 mentions) Epiq 7c system, by Philips (1 mentions) Vantage system, by Verasonics (1 mentions) L7 4 probe, by Philips (1 mentions) S12 4, by Philips (1 mentions)

117 protocols using ie33 system

Anthropometric and Echocardiographic Measurements in Pregnancy

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A range of anthropometric parameters were measured for each participant, including weight, height, heart rate, systolic blood pressure, and diastolic blood pressure; we also calculated the BMI [10 (link)]. At each visit, we also recorded the family history of diabetes as a parent or sibling may have been diagnosed as having diabetes in the interval since the previous visit [11 (link)].
A peripheral blood sample was collected from each participant before 19 weeks + 6 days; samples were collected in a vacutainer collection tube. We used the blood samples to determine the lipid profile of each participant, including triglyceride, total cholesterol, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C); these parameters were determined with an auto-analyzer (AU1000; Olympus, Tokyo, Japan).
Maternal echocardiography was also performed between 16 weeks + 0 days and 19 weeks + 6 days. All images were obtained using a Philips iE33 system (Philips Medical Systems, Bothell, WA, USA) with a 1.5/5 MHz phased array probe. Maternal EAT thickness was measured by echocardiography in the parasternal long-axis view at the level of the fold of Rindfleisch, between the free wall of the right ventricle and the anterior surface of the ascending aorta [12 (link)].

Liu J., Song G., Meng T, & Zhao G. (2020). Epicardial adipose tissue thickness as a potential predictor of gestational diabetes mellitus: a prospective cohort study. BMC Cardiovascular Disorders, 20, 184.

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Comprehensive Echocardiographic Assessment Protocol

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Echocardiography studies were performed by an experienced cardiologist, using a Philips iE33 System (Philips Medical Systems, Bothell, WA, USA), equipped with a phased-array transducer (5–1 MHz). ProSolv CardioVascular Analyzer software version 3.5 (Mount International Ultrasound Services Ltd, The Glenmore Centre, Gloucester, UK) was used for reporting, frame-by-frame analysis, and quantification of the lesions.
2D echo and color Doppler were performed according to the recommendations of the American Society of Echocardiography and the European Association of Echocardiography, using a standardized protocol. Assessment included the evaluation of function and morphology of cardiac valves. Valvular regurgitation was graded as absent/trace (Grade 0), mild (Grade 1), moderate (Grade 2), or severe (Grade 3) using multiple parameters. Moderate or severe valvular regurgitation was considered clinically significant dysfunction. Valve leaflet mobility, thickness (>0·5 cm is significant), and calcification were noted. In addition, thickening of the chordae tendineae was also recorded.

Khare S., Lila A.R., Patil R., Phadke M., Kerkar P., Bandgar T, & Shah N.S. (2017). Long-term cardiac (valvulopathy) safety of cabergoline in prolactinoma. Indian Journal of Endocrinology and Metabolism, 21(1), 154-159.

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Hemodynamics Changes in Model Rats

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Upon completion of the experiments, the changes in hemodynamics parameters of model rats, including interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), aortic diameter (AO), left ventricular internal diameter (LV), and right atrium diameter (RV) were measured using the algorithms of ultrasound system using Philips iE33 system (Philips Ultrasound, Bothell, WA). Then rats were sacri ced with i.p. injection of overdose (200 mg/kg body weight) pentobarbital sodium, and the abdominal aorta tissues and blood samples were collected for subsequent detections.

Zhou T., Sun D., Hou Y., & Zhang Z. (2021). Suppression of miR-21-5p by Ginsenoside Rb1 Prevents Atherosclerosis and Attenuates Endothelial Dysfunction by Inducing KRIT1.

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3D Cardiac Imaging and LV Measurement

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Three-dimensional (3D) imaging of the heart was performed using Philips IE 33 system (Koninklijke Philips N.V, Amsterdam, The Netherlands). The 3D images were obtained with the subject in the supine position over four cardiac cycles during a breath hold. Semiautomatic detection of the heart contour was performed after identifying specific heart points. A 3D endocardial volume of the LV was then produced from which LV volumes were calculated. Measurements of 3D LV volumes were performed (Q-Lab; Koninklijke Philips N.V, Amsterdam, The Netherlands) by one experienced echocardiographer. Left ventricular mass (LVM) was measured according to current guidelines [19 (link)], by two-dimensional guided M-mode from both parasternal short and long-axis views. Echocardiography measurements have been shown to be reasonably accurate and reproducible [19 (link),20 (link)]. Measurements were made in duplicate from both views, by a single observer, and averaged. The results were adjusted for lean mass and body surface area.

Ek S., Wollmer P., Karlsson M.K., Peterson T., Thorsson O., Olsson M.C., S. Malmborg J, & Dencker M. (2020). Relative Age Effect of Sport Academy Adolescents, a Physiological Evaluation. Sports, 8(1), 5.

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Retrospective Study of Pediatric and Adult WPW

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The retrospective study was performed. The study group comprised 43 consecutive paediatric patients with an average age of 14 ± 2.5 years and 43 consecutive adult patients with an average age of 41 ± 15 years (Table 1). Patients with WPW were referred to electrophysiological study (EPS) and CA between 2016 and 2017. Diagnosis of WPW and the accessory pathways (AP) location were based on 12-lead standard electrocardiogram (ECG) using the Lucas Boersma algorithm before the procedure and confirmed during EPS [2 (link)]. In all patients, a morphologically normal heart was confirmed by echocardiography using the Philips iE33 system (Philips Medical Systems, Andover, MA, USA).

Pietrzak R., Franke M., Gawałko M., Lodziński P., Balsam P., Grabowski M, & Werner B. (2022). Success rate and safety of catheter ablation in preexcitation syndrome: A comparison between adult and pediatric patients. Cardiology Journal, 29(1), 88-92.

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Left Atrial Appendage Measurement Protocol

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Standard TEE views were acquired as per recommendations of the American Society of Echocardiography guidelines using 5 MHz multi-plane probe with commercially available scanners (GE Vivid E9; Vingmed Ultrasound, Horten, Norway, Philips IE33 system; Phillips Medical Systems, Andover, MA, USA).6) (link) LAA was observed at best image between 45 to 90° including 2-dimensional, color Doppler images and pulsed-wave Doppler. Fractional area change (FAC_TEE) was calculated by dividing maximum area of LAA from the difference between maximum and minimum area of LAA (Figure 1). Peak end-diastolic emptying velocity at LAA in TEE view (Ve_TEE) was the mean of 3 consecutive values by pulsed-wave Doppler at LAA ostium. SEC was defined as smoke-like swirling pattern observed in LA or LAA after adjustment of optimal gain setting.7) (link)

Kim I.C., Chang H.J., Cho I.J., Shim C.Y., Hong G.R., Heo J.H., Nam H.S., Kim Y.J., Choi B.W, & Chung N. (2018). Benefit of Four-Dimensional Computed Tomography Derived Ejection Fraction of the Left Atrial Appendage to Predict Thromboembolic Risk in the Patients with Valvular Heart Disease. Korean Circulation Journal, 49(2), 173-180.

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Echocardiographic Evaluation of Cardiac Function

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At baseline, all subjects underwent transthoracic echocardiographic studies (TTE) by Philips IE33 system (Phillips Medical Systems, Andover, MA, USA). TTE images were acquired using the IE33 with an S5-1 transducer or EPIQ7 X5-1 transducer. All images were interpreted by a single echocardiography specialist who was blinded from clinical details.
Left ventricular ejection fraction (LVEF) was assessed by the modified Simpson’s biplane method. Other parameters such as left ventricular mass index (LVMI), left atrial volume index (LAVi), and diastolic function were determined according to the recommendations by the American Society of Echocardiography [27 (link)]. With the sample volume placed at medial and lateral mitral annulus in four-chamber apical view, pulsed-wave tissue Doppler imaging was used to measure the peak diastolic mitral inflow velocity (E.) and mitral annulus early diastolic tissue velocity (e’).

Ng J.K., Chan G.C., Kam K.K., Tian N., Than W.H., Cheng P.M., Law M.C., Pang W.F., Szeto C.C, & Li P.K. (2022). The Impact of Volume Overload on the Longitudinal Change of Adipose and Lean Tissue Mass in Incident Chinese Peritoneal Dialysis Patients. Nutrients, 14(19), 4076.

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Echocardiography and Hemodynamics in Rats

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At the end of I/R procedure, left ventricular end systolic pressure (LVESP) and left ventricular end-diastolic pressure (LVEDP) were monitored with six awake rats in each group with a non-invasive blood pressure system (XBP 1000, Kent Scientific, Torrington, CT, USA) according to the manufacturer’s instruction. Briefly, the rats were fastened in a restrainer for a long period for the acclimation to the device, which was judged by the absence of struggling. The factional shortening (FS) was calculated by assuming a spherical left ventricular geometry with the algorithms of ultrasound system using Philips iE33 system (Philips Ultrasound, Bothell, WA, USA). All the parameters were represented by at least three replicates.
After the measurement of hemodynamics parameters, heart tissues of rats in different treatments were harvested and preserved in -80°C for H&E staining, TTC staining, and further analysis.

Yu H., Shi L., Qi G., Zhao S., Gao Y, & Li Y. (2016). Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Frontiers in Pharmacology, 7, 148.

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Pulmonary Hypertension and Vaso-Occlusive Crises in Sickle Cell Disease

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Charts were retrospectively reviewed by 3 physicians to recognize all ACS and VOC episodes from birth to the time of blood sampling, based on previously described criteria [7 (link)]. The rates of VOC were calculated for each child by dividing the total number of painful VOC episodes by the number of patient-years [7 (link)] and two subgroups were constituted according to the median VOC rate. The tricuspid regurgitant jet velocity (TRJV), available for 102 children at steady-state, was also recorded. The Philips IE33 system (Philips Medical Systems, Bothell, WA) was used for evaluating pulmonary hypertension according to the criteria of the American Society of Echocardiography [29 (link)]. A TRJV ≥ 2.5 m/sec was considered abnormal [30 (link)–31 (link)].

Garnier Y., Ferdinand S., Etienne-Julan M., Elana G., Petras M., Doumdo L., Tressières B., Lalanne-Mistrih M.L., Hardy-Dessources M.D., Connes P, & Romana M. (2017). Differences of microparticle patterns between sickle cell anemia and hemoglobin SC patients. PLoS ONE, 12(5), e0177397.

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Echocardiographic Imaging Systems Comparison

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Echocardiography was performed using a GE LOGIQ E9 XDclear 2.0 system (GE Healthcare, Milwaukee, WI, USA) fitted with a 1.5‐4.6‐MHz sector probe, a GE Vivid7 system (GE Healthcare) fitted with a 1.5‐4.0‐MHz sector probe, a Philips IE33 system (Philips Medical, Best, Netherlands) fitted with a 1‐5‐MHz sector probe, or a Philips SONOS 7500 system (Philips Medical) fitted with a 1‐3‐MHz sector probe.

Kobayashi S., Muto M., Yabe H., Imao M, & Okada Y. (2020). A retrospective observational study investigating the factors associated with right heart failure in patients with primary acute pulmonary embolism and deep vein thrombosis. Journal of General and Family Medicine, 21(3), 63-70.

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