Tetraethoxysilane

Manufactured by Merck Group

Sourced in United States, Germany, France, China

Tetraethoxysilane is a silicon-based organic compound with the chemical formula Si(OC2H5)4. It is a clear, colorless liquid used as a precursor in the production of silica-based materials and coatings.

Automatically generated - may contain errors

Lab products found in correlation

Close spelling variants of this product

Tetraethoxysilane—TEOS 99.99% (2 citations) Tetraethoxysilane (TEOS) (22 citations)

59 protocols using tetraethoxysilane

Synthesis and Characterization of SNP Variants

Check if the same lab product or an alternative is used in the 5 most similar protocols

This study examined three types of SNPs: spherical (S-SNPs), mesoporous (M-SNPs) and PEGylated (P-SNPs; PEG, polyethylene glycol). To prepare the S-SNPs, 11.87 ml of ethanol (Sigma-Aldrich, St. Louis, MO, USA), 2.1 ml of distilled (DI) water, 0.67 ml of tetraethoxysilane (Sigma-Aldrich) and 0.36 ml of 5 M NH₄OH (Sigma-Aldrich) were mixed in a vial and stirred for 24 h.
M-SNPs were synthesized using 53.4 g of DI water, 6.24 g of cetyltrimethylammonium chloride (Sigma-Aldrich) and 0.3 g of sodium acetate (Sigma-Aldrich), were mixed well, and then heated in a 65 °C oil bath. After heating for 1 h, 3.9 ml of tetraethoxysilane was slowly added to the mixture and then stirred for 24 h. The resulting suspensions were purified by centrifugation, re-dispersed in ethanol and DI water, and then finally re-dispersed in DI water.
P-SNPs were prepared by surface functionalization of S-SNP. Briefly, thiol-functionalized S-SNP was prepared by adding (3-mercaptopropyl) trimethoxysilane (10% of tetraethoxysilane) 5 h after the addition of NH₄OH during synthesis of S-SNP. After purification, these particles were conjugated with maleimide-functionalized PEG (molecular weight: 2000) in DI water for 24 h (weight ratio: ~0.5:1). Excess amount of PEG was removed by centrifugation and dispersed in DI water to obtain P-SNP.

Park H.J., Sohn J.H., Kim Y.J., Park Y.H., Han H., Park K.H., Lee K., Choi H., Um K., Choi I.H., Park J.W, & Lee J.H. (2015). Acute exposure to silica nanoparticles aggravate airway inflammation: different effects according to surface characteristics. Experimental & Molecular Medicine, 47(7), e173-.

+ Open protocol

+ Expand

Fabrication of Titania-Silica Gels and Rhodium Catalysts

Check if the same lab product or an alternative is used in the 5 most similar protocols

In the preparation procedure for titania-silica gels the following reagents were used: aqueous ammonia 25% analytical purity grade (cz.d.a.) POCH Gliwice (Poland); Isopropyl alcohol cz.d.a., POCH Gliwice (Poland); Tetraethoxysilane, Sigma Aldrich, purified by distillation; Tetraethoxytitanium, 97% purity, Sigma Aldrich. For the preparation of rhodium catalysts, rhodium (III) chloride hydrate (Rh, 38–40%) (Sigma Aldrich) was used.

Wasilewska J., Chmielarek M, & Skupiński W. (2021). Study of Rh/TiO2–SiO2 system in photolytic water splitting. Reaction Kinetics, Mechanisms and Catalysis, 132(2), 1165-1192.

+ Open protocol

+ Expand

Synthesis of Superparamagnetic Nanochains

Check if the same lab product or an alternative is used in the 5 most similar protocols

The chemicals used for the synthesis of the superparamagnetic nanochains were of reagent grade quality and were obtained from commercial sources. Primary magnetic nanoparticle clusters were provided by Nanos SCI company (Ljubljana, Slovenia), and are commercially sold as iNANOvative™ (Nanos SCI, Ljubljana, Slovenia). Succinic anhydride (SA, 99%) and NH₄OH (28–30%) were supplied by Alfa Aesar (Lancashire, UK). Acetone (AppliChem GmbH, Darmstadt, Germany) and ethanol absolute (Carlo Erba, reagent—USP, Milano, Italy) were used without further processing. Hydroxy (polyethyleneoxy) propyl triethoxysilane (silane-PEG, 50% in ethanol) was supplied by Gelest Inc. (Morrisville, PA, USA). Tetraethoxysilane (TEOS; 98%), rhodamine B isothiocyanate (RB), (3-aminopropyl) triethoxysilane (APS; silane-NH2, 99%), dichloromethane (DCM), dimethylformamide (DMF), Keiser test kit, and polyvinyl pyrrolidone (PVP, 40 kDa) were obtained from Sigma Aldrich (St. Louis, MO, USA).

Kolosnjaj-Tabi J., Kralj S., Griseti E., Nemec S., Wilhelm C., Plan Sangnier A., Bellard E., Fourquaux I., Golzio M, & Rols M.P. (2019). Magnetic Silica-Coated Iron Oxide Nanochains as Photothermal Agents, Disrupting the Extracellular Matrix, and Eradicating Cancer Cells. Cancers, 11(12), 2040.

+ Open protocol

+ Expand

Synthesis of Silica-based Biosensor Materials

Check if the same lab product or an alternative is used in the 5 most similar protocols

Ethanediamine (EDA, 99%), formaldehyde (30–40%), ethyl alcohol (99.7%), 3-aminophenol (99%), ethylenediamine tetraacetic acid disodium salt (EDTA·2Na, 99%), H₂SO₄ (95–98%), HCl (36–38%), NH₃·H₂O (25–28%), and BaCl₂·2H₂O (99.5%) were purchased from Sinopharm Chemical Reagent (Shanghai, China). NaOH (96%) and Na₂SO₄ (99%) were purchased from Shanghai Dahe Chemicals (Shanghai, China). NaH₂PO₄·2H₂O (99%), and Na₂HPO₄·12H₂O (99%) were purchased from Chinasun Specialty Product (Changshu, China). Tetraethoxysilane (TEOS, 99%), catalase (from bovine liver, 2000–5000 units/mg protein), 3,3′,5,5′-tetramethylbenzidine (TMB, 98%), and peroxidase from horseradish (HRP, ~200 units/mg) were purchased from Sigma–Aldrich (St. Louis, MO, USA). All chemicals were used without further purification.

Zhang Q., Wu M., Fang Y., Deng C., Shen H.H., Tang Y, & Wang Y. (2022). Dendritic Mesoporous Silica Hollow Spheres for Nano-Bioreactor Application. Nanomaterials, 12(11), 1940.

+ Open protocol

+ Expand

Synthesis of Nanostructured Silica Materials

Check if the same lab product or an alternative is used in the 5 most similar protocols

Acetonitrile and methanol (HPLC grade) were purchased from Fisher Scientific (Hampton, NH, USA). The SEA-NINE™ 211N (30% of DCOIT in xylene) was obtained from Rohm and Haas (Philadelphia, PA, USA). Tetraethoxysilane (TEOS, 99.9%), cetyltrimethylammonium bromide (CTAB, >98%) was supplied by Sigma-Aldrich (St. Louis, MO, USA). Pro-Reef salt was purchased from Tropic Marin^® (Wartenberg, Germany). Analytical grade xylene was provided by Labscan (Rio Janeiro, Brazil). All other chemicals were obtained from Riedel-de-Haën (Charlotte, NC, USA).

Ferreira V., Figueiredo J., Martins R., Sushkova A., Maia F., Calado R., Tedim J, & Loureiro S. (2023). Characterization and Behaviour of Silica Engineered Nanocontainers in Low and High Ionic Strength Media. Nanomaterials, 13(11), 1738.

+ Open protocol

+ Expand

Synthesis of γ-Fe2O3/SiO2/RhB Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

For the synthesis of the γ-Fe₂O₃/SiO₂/RhB NPs, reagent grade chemicals were used as received from the manufacturers. Iron (III) sulfate hydrate, iron (II) sulfate heptahydrate (ACS, 99%), citric acid (CA, 99%), tetraethoxysilane (TEOS, 99.9%) and NH₄OH (28–30%) were supplied by Alfa Aesar (Lancashire, UK). Acetone (AppliChem GmbH) and absolute ethanol (Carlo Erba, reagent - USP) were used as received. (3-Aminopropyl)triethoxysilane (APS; silane-NH₂, 99%), tetraethoxysilane (TEOS; 98%), ethyl acetate (EA), dichloromethane (DCM), dimethylformamide (DMF), Rhodamine B isothiocyanate (RhB), poly(acrylic acid) solution (25 wt. % in water) and polyvinyl pyrrolidone (PVP, 40 kDa) were obtained from Sigma-Aldrich (St. Louis, MO, USA).
Cellulose acetate (CA, Mn = 30000 g/mol) was obtained from Sigma-Aldrich and used without further purification. Acetone (Technical Grade 99.5% - Panaska Trading CO) was the solvent used in the preparation of CA polymer solutions that were further electrospun.

Petropoulou A., Kralj S., Karagiorgis X., Savva I., Loizides E., Panagi M., Krasia-Christoforou T, & Riziotis C. (2020). Multifunctional Gas and pH Fluorescent Sensors Based on Cellulose Acetate Electrospun Fibers Decorated with Rhodamine B-Functionalised Core-Shell Ferrous Nanoparticles. Scientific Reports, 10, 367.

+ Open protocol

+ Expand

Antimicrobial Copper Silica Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

Tetraethoxysilane (TEOS), ammonium hydroxide (NH₃·H₂O, 28%), cupric nitrate trihydrate (Cu(NO₃)₂·3H₂O), and lipopolysaccharide (LPS) were purchased from Sigma-Aldrich (Shanghai, China), Cefoperazone (CFP, CAS: 62893-19-0) was purchased from Macklin. All reagents were applied as received with no further purification.
BALB/c mice (male, 20–25 g) were provided by the Laboratory Animals Department of the Army Medical University (AMU, Chongqing, China). All animal experiments were performed according to ethical standards and with the approval of AMU's Institutional Animal Care and Use Committee. The experimental mice were housed individually in plastic cages with free access to autoclaved standard rodent chow and water under standard conditions (Room temperature: 25 °C; relative humidity: 50%; circadian rhythm: 12 h). All mice were fed adaptively for 1 week before the experiment.
Multi-drug resistant Pseudomonas aeruginosa (P. aeruginosa, ATCC 27853) was provided by the Clinical Microbiology Laboratory, Institute of Burn Research, Southwest Hospital, AMU (Chongqing, China). NIH 3T3 cells and RAW264.7 cells were provided from the Chinese Academy of Science Cell Bank for Typical Culture Collection.

Peng Z., Zhang X., Yuan L., Li T., Chen Y., Tian H., Ma D., Deng J., Qi X, & Yin X. (2021). Integrated endotoxin-adsorption and antibacterial properties of platelet-membrane-coated copper silicate hollow microspheres for wound healing. Journal of Nanobiotechnology, 19, 383.

+ Open protocol

+ Expand

Synthesis of Silica Nanoparticles with Arginine

Check if the same lab product or an alternative is used in the 5 most similar protocols

We used styrene (99%), sodium persulfate (99%), Symperonic^® NP30, sodium dodecylsulfate (SDS, >90%), tetraethoxysilane (TEOS, 99%), l-arginine (98.5%) and ammonium hydroxide (28–30% in water), as we received them from Sigma Aldrich (Saint-Quentin-Fallavier, France). We purchased absolute ethanol from VWR International S.A.S (Fontenay-sous-Bois, France) and methacryloxymethyltriethoxysilane (MMS, 98%) from abcr GmbH (Karlsruhe, Germany) and used them as received. We systematically used ultrapure water with a resistivity of 18.2 MΩ·cm at 25 °C obtained from a Milli-Q system (Merck Millipore, Molsheim, France).

Liu B., Exiga S., Duguet E, & Ravaine S. (2021). Templated Synthesis and Assembly of Two-, Three- and Six-Patch Silica Nanoparticles with a Controlled Patch-to-Particle Size Ratio. Molecules, 26(16), 4736.

+ Open protocol

+ Expand

Synthesis and Characterization of Multimodal Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

Ethylene glycol (EG), sodium chloride (NaCl), silver nitrate (AgNO₃, purity of 99.8%), polyvinyl pyrrolidone (PVP, with a molecular weight of approximately 55,000), gold chloride trihydrate (HAuCl₄·3H₂O, purity of 99%), tetraethoxysilane (TEOS, purity of 98%), and (3-aminopropyl) triethoxysilane (APTES, purity of 98%) were all purchased from Sigma-Aldrich. Nile Red was obtained from Selleck Chemicals LLC, while HA was sourced from J&K Scientific. The anti-PD1 antibody was a generous gift from Conmed Biosciences Inc. Dulbecco’s Modified Eagle’s Medium (DMEM) was procured from Gibco Life Technologies. Streptomycin, penicillin, and trypsin-EDTA were acquired from Merck Millipore. Fetal bovine serum (FBS) was procured from Gibco Life Technologies.

Xiao G., Zhao Y., Wang X., Zeng C., Luo F, & Jing J. (2023). Photothermally sensitive gold nanocage augments the antitumor efficiency of immune checkpoint blockade in immune “cold” tumors. Frontiers in Immunology, 14, 1279221.

+ Open protocol

+ Expand

Quantitative Determination of Hordenine via HPLC-MS/MS

Check if the same lab product or an alternative is used in the 5 most similar protocols

N,N-Dimethylphenethylamine (template), methacrylic acid (functional
monomer), ethylene glycol dimethacrylate (cross-linker), tetraethoxysilane,
3-(trimethoxysilyl)propyl methacrylate (MPS), and 2,2′-azobis(2-methylpropionitrile)
(initiator) were purchased from Sigma-Aldrich (Steinheim, Germany, http://www.sigmaaldrich.com). Internal standard (IS), hordenine-d₆ was purchased from Toronto Research Chemicals (Toronto, Canada, https://www.trc-canada.com). Trisodium citrate dehydrate, sodium hydroxide, sodium nitrate,
ferrous sulfate heptahydrate, ammonium acetate, ammonium hydroxide,
methanol, ethanol, toluene, acetonitrile, formic acid, and acetone
were delivered from POCh (Gliwice, Poland, http://www.poch.com.pl). Ultrapure
water was delivered from a Hydrolab HLP 5 system (Straszyn, Poland, http://www.hydrolab.pl). Dietary
supplement (Hordenine 98%, 100 mg, 60 capsules) was purchased from
Haya Labs (Washington DC, United States, https://www.hayalabs.com).

Sobiech M., Giebułtowicz J, & Luliński P. (2020). Application of Magnetic Core–Shell Imprinted Nanoconjugates for the Analysis of Hordenine in Human Plasma-Preliminary Data on Pharmacokinetic Study after Oral Administration. Journal of Agricultural and Food Chemistry, 68(49), 14502-14512.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!