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Recombinant mouse il 21r fc chimera protein

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Recombinant mouse IL-21R Fc Chimera protein is a soluble fusion protein consisting of the extracellular domain of the mouse Interleukin-21 Receptor (IL-21R) and the Fc portion of human IgG1. It is produced in a mouse myeloma cell line.

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Lab products found in correlation

Ifn γ xmg1.2, by Thermo Fisher Scientific (2 mentions) Cd25 pc61, by Thermo Fisher Scientific (2 mentions) Cd44 im7, by BD (2 mentions) Cd3ε γ 17a2, by BioLegend (2 mentions) Cd62l mel 14, by Thermo Fisher Scientific (2 mentions) Cd126 d7715a7, by Thermo Fisher Scientific (2 mentions) Cd127 25 1271 82, by Thermo Fisher Scientific (2 mentions) βtcr h57 597, by R&D Systems (2 mentions) Gp130 125623, by R&D Systems (2 mentions) Il 4 11b11, by Thermo Fisher Scientific (2 mentions) Il 21 receptor antibody, by Jackson ImmunoResearch (2 mentions) Af1930, by R&D Systems (2 mentions) Uchl1, by BioLegend (2 mentions) Dreg 56, by BD (2 mentions) Cd197 ccr7 g043h7, by BioLegend (2 mentions) Rpa t4, by Thermo Fisher Scientific (2 mentions) Cd4 rm4 5, by Thermo Fisher Scientific (2 mentions)

Close spelling variants of this product

IL-21R/Fc chimera Mouse IL-21R–Fc Recombinant proteins

2 protocols using recombinant mouse il 21r fc chimera protein

1

Characterization of T Cell Subsets

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Mouse specific antibodies against CD3ε/γ (17A2; Biolegend), CD4 (RM4-5; eBioscience), CD25 (PC61.5; eBioscience), CD44 (IM7; BD Biosciences), CD62L (MEL-14; Life Technologies), CD126 (D7715A7; eBioscience), CD127 (25-1271-82; eBioscience),βTCR (H57-597), gp130 (125623; R&D Systems), IFNγ (XMG1.2; eBioscience), IL-4 (11B11; eBioscience), IL-17A (TC11-18H10.1; Biolegend), IL-21 (Recombinant mouse IL-21R Fc Chimera protein; R&D and IL-21 receptor antibody; Jackson Immuno Research) and PTPN2 (AF1930; R&D) were used. For detection of human antigens, we used antibodies specific to CD3 (UCHT1; BioLegend), CD4 (RPA-T4; eBioscience), CD45RA (HI100; BioLegend), CD45RO (UCHL1; BioLegend), CD62L (DREG-56; BD Biosciences), CD197 (CCR7; G043H7; BioLegend). Human and mouse cross-specific antibodies to pY STAT1 (pY701; 4a), pY-STAT3 (pY705; 4/P-STAT3), pS-STAT1 (pS727; K51-856) and pS STAT3 (pS727, 49/p-Stat3) were from BD Biosciences.
Twohig J.P., Figueras A.C., Andrews R., Wiede F., Cossins B.C., Soria A.D., Lewis M.J., Townsend M.J., Millrine D., Li J., Hill D.G., Fernandez J.U., Liu X., Szomolay B., Pepper C.J., Taylor P.R., Pitzalis C., Tiganis T., Williams N.M., Jones G.W, & Jones S.A. (2019). Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature immunology, 20(4), 458-470.
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2

Characterization of T Cell Subsets

Check if the same lab product or an alternative is used in the 5 most similar protocols
Mouse specific antibodies against CD3ε/γ (17A2; Biolegend), CD4 (RM4-5; eBioscience), CD25 (PC61.5; eBioscience), CD44 (IM7; BD Biosciences), CD62L (MEL-14; Life Technologies), CD126 (D7715A7; eBioscience), CD127 (25-1271-82; eBioscience),βTCR (H57-597), gp130 (125623; R&D Systems), IFNγ (XMG1.2; eBioscience), IL-4 (11B11; eBioscience), IL-17A (TC11-18H10.1; Biolegend), IL-21 (Recombinant mouse IL-21R Fc Chimera protein; R&D and IL-21 receptor antibody; Jackson Immuno Research) and PTPN2 (AF1930; R&D) were used. For detection of human antigens, we used antibodies specific to CD3 (UCHT1; BioLegend), CD4 (RPA-T4; eBioscience), CD45RA (HI100; BioLegend), CD45RO (UCHL1; BioLegend), CD62L (DREG-56; BD Biosciences), CD197 (CCR7; G043H7; BioLegend). Human and mouse cross-specific antibodies to pY STAT1 (pY701; 4a), pY-STAT3 (pY705; 4/P-STAT3), pS-STAT1 (pS727; K51-856) and pS STAT3 (pS727, 49/p-Stat3) were from BD Biosciences.
Twohig J.P., Figueras A.C., Andrews R., Wiede F., Cossins B.C., Soria A.D., Lewis M.J., Townsend M.J., Millrine D., Li J., Hill D.G., Fernandez J.U., Liu X., Szomolay B., Pepper C.J., Taylor P.R., Pitzalis C., Tiganis T., Williams N.M., Jones G.W, & Jones S.A. (2019). Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature immunology, 20(4), 458-470.
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