Neurofax eeg 1200

Manufactured by Nihon Kohden

Sourced in Japan

The Neurofax EEG-1200 is a diagnostic electroencephalography (EEG) system designed for clinical use. It is capable of recording and displaying electrical activity in the brain.

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Lab products found in correlation

Je 120 amplifier, by Nihon Kohden (1 mentions) Nicoletone icu monitor, by Natus (1 mentions) Xltek eeg, by Natus (1 mentions) Matlab, by MathWorks (1 mentions)

21 protocols using neurofax eeg 1200

Resting-State EEG Dynamics in SAHC Treatment

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The data acquisition was performed in three experimental time instances: before SAHC, SAHC alone in both protocols, and SAHC combined with exercise on the resting state (eyes closed) condition. The patient was instructed to close her eyes and remain calm for approximately 5 min. In case there were artifacts due to body movements, opening of eyes, or a muscle/body movement, the recording session was extended proportionally. The room temperature was kept at a relatively stable condition (22°C) through artificial cooling, and the room lights were turned off. The operators also kept auditory noise minimal.
The EEG device was the 32-channel Neurofax EEG-1200 connected to a laptop (Nihon Kohden, Tokyo, Japan). Among those electrodes, there were 1) 19 EEG electrodes placed according to the 10–20 International System, 2) two electromyographic/EMG electrodes for recording chin movements, 3) two electrodes for electroculogrammic/EOG (both horizontal and vertical) recordings, and finally, 4) two electrocardiographic/ECG electrodes. Apart from the electrodes used for EEG data, all the others (ECG, EMG, and EOG) were bipolar. The ground electrode was placed on the prefrontal midline (Fpz) position. There were also two reference electrodes placed on the left and right mastoid muscles. The sampling frequency was kept at 500 Hz for all the signals.

Kourtidou-Papadeli C., Frantzidis C., Machairas I., Giantsios C., Dermitzakis E., Kantouris N., Konstantinids E., Bamidis P, & Vernikos J. (2023). Rehabilitation assisted by Space technology—A SAHC approach in immobilized patients—A case of stroke. Frontiers in Physiology, 13, 1024389.

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Standardized EEG Monitoring in Seizure Emergencies

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We performed routine video EEG for ≥20 min as soon as possible after admission, using the international 10-20 system with 21 electrodes (Neurofax EEG-1200; Nihon Kohden, Tokyo, Japan), and repeated as clinically needed. The bandpass filters were set at 0.5 and 120 Hz. The initial EEG recordings were reviewed by a board-certified neurophysiologist (R.M.) or neurologist (H.Y.) blinded to the patients' clinical information other than the diagnosis of SE. Continuous or abundant (i.e., present for > 50% of the recording period) rhythmic or periodic patterns were regarded as IIC, and classified according to the American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology 2012 version [34] , using "main term 1" (generalized [G], lateralized [L], bilateral independent [BI], and multifocal [Mf]) and "main term 2" (periodic discharges [PDs], rhythmic delta activity [RDA], and spike-and-wave [SW]). These two main terms have been demonstrated to have high interrater agreement [35] . The following patterns without IIC were considered "conventional seizure patterns": generalized spike-wave discharges of ≥3 Hz; and clearly evolving discharges of any type that reached a frequency of > 4 Hz, whether focal or generalized.

Yoshimura H., Matsumoto R., Ueda H., Ariyoshi K., Ikeda A., Takahashi R, & Kohara N. (2018). Status epilepticus in the elderly: Comparison with younger adults in a comprehensive community hospital. Seizure, 61.

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Standardized EEG Acquisition Protocol

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The EEG recordings were performed according to the recommendations of the American Society for Electroen-cephalography, with the standard 10-20 system of electrode placement [24 (link)], using a digital EEG instrument (Neurofax EEG-1200; Nihon-Kohden, Tokyo, Japan).
The ipsilateral earlobes were used as a reference for all EEG electrodes. Ag/AgCl electrodes were used, and the impedance was maintained below 5 kΩ. The EEG data were filtered (time constant, 0.16 seconds; high-frequency filter, 100 Hz) and digitized (sampling rate, 500 Hz). The recordings were performed in a sound-attenuated room that had subdued lightning, and patients were in a semi- recumbent position with their eyes closed but in a maximally alert state. The alertness of patients was controlled during the recording. If patterns of drowsiness appeared in the EEG recordings, the subjects were aroused by acoustic stimulation.

Ozaki T., Toyomaki A., Hashimoto N, & Kusumi I. (2021). Quantitative Resting State Electroencephalography in Patients with Schizophrenia Spectrum Disorders Treated with Strict Monotherapy Using Atypical Antipsychotics. Clinical Psychopharmacology and Neuroscience, 19(2), 313-322.

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EEG Recording and Analysis Methodology

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The participants’ EEG responses were measured using a digital amplifier (Neurofax EEG1200; Nihon-Kohden), and silver-silver chloride electrodes were placed at 27 scalp sites (Fp1, Fp2, F7, F3, Fz, F4, F8, FCz, T3, C3, Cz, C4, T4, T5, CPz, P3, Pz, P4, T6, PO7, PO8, O1, Oz, O2, O9, Iz, and O10, according to the extended International 10–20 System), with AFz as the ground electrode. To monitor eye movements, a vertical electrooculogram (EOG) was recorded using electrodes placed above and below the right eye, and a horizontal EOG was recorded from the outer left and right canthi. The impedances of all electrodes were kept below 10 kΩ. The EEG and EOG signals were digitized at a sampling rate of 1000 Hz, and the time constant was set to 5 s. The EEG signals were re-referenced to mathematically averaged earlobes (A1-A2) off-line. The EEG and EOG signals were band-pass filtered at 0.1–30 Hz using a second-order Butterworth filter.

Tsuzuki T., Takeda Y, & Chiba I. (2019). Effortful Processing Reduces the Attraction Effect in Multi-Alternative Decision Making: An Electrophysiological Study Using a Task-Irrelevant Probe Technique. Frontiers in Psychology, 10, 896.

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Intracranial ECoG for Epilepsy Localization

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Extraoperative ECoG recordings were continuously recorded with a video for 3-14 days using NeurofaxEEG-1200 with a JE-120 amplifier (Nihon Koden, Tokyo, Japan). All AEDs were withdrawn until a sufficient number of habitual seizures were captured. Two board-certified epileptologists of Japan epilepsy society visually identified interictal epileptic discharges and also reviewed ECoG during seizures to reach a consensus on the seizure onset region. The distribution of cECoG spikes was defined as the areas in which interictal spikes were identified during the recording periods. cECoG recordings from intracranial electrodes were obtained under the following settings: a sampling rate of 2000 Hz, low filter setting of 0.016 Hz, and high filter setting of 600 Hz using Neurofax EEG-1200 with the JE-120 amplifier (Nihon Kohden, Tokyo, Japan). These recordings were analyzed with band-pass filtering between 5 and 600 Hz to localized interictal spike and seizure onset zones.

CHIBA R., ENATSU R., KANNO A., TAMADA T., SAITO T., SATO R, & MIKUNI N. (2022). Usefulness of Intraoperative Electrocorticography for the Localization of Epileptogenic Zones. Neurologia medico-chirurgica, 63(2), 65-72.

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Prolonged Video cEEG Monitoring of Infants

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All infants underwent prolonged video cEEG monitoring as clinically indicated, using a 10:20 EEG electrode modified neonatal system with disposable electrodes placed at F3, F4, C3, C4, Cz, T3, T4, O1/P3, and O2/P4. Three different EEG machines were used for monitoring: Neurofax EEG-1200 (Nihon Kohden), NicoletOne ICU Monitor (Natus), and XLTek EEG (Natus). Teams at each site were trained in EEG electrode application and maintenance of good quality recordings. The clinical teams at each site had the aEEG signals from F3-C3 and F4-C4, 8 raw EEG channels, and electrocardiography and respiratory traces displayed on the EEG monitors and available to review. No standard EEG review protocol was imposed during the study period, and the clinical teams reviewed the monitoring data as recommended by the local guidelines.

Pavel A.M., Rennie J.M., de Vries L.S., Blennow M., Foran A., Shah D.K., Pressler R.M., Kapellou O., Dempsey E.M., Mathieson S.R., Pavlidis E., Weeke L.C., Livingstone V., Murray D.M., Marnane W.P, & Boylan G.B. (2022). Neonatal Seizure Management: Is the Timing of Treatment Critical?. The Journal of Pediatrics, 243, 61-68.e2.

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EEG Frequency Analysis Protocol

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EEG recordings were acquired with Neurofax EEG-1200 (Nihon Kohden, Tokyo, Japan) using Ag/AgCl electrodes at a sampling rate of 200 Hz. A total of 19 electrodes were carefully placed on the scalp by a trained research technologist following the International 10–20 system, and all electrodes were referenced to the ground electrode located at the FPz position. After visual inspection of artifact rejection, a 10-s EEG recording during the eye-closed waking state was retrieved for further analysis. Digitized EEG data were processed offline using in-house MATLAB scripts developed for frequency analyses, which were transformed into frequency domains via a power spectral density (PSD) function (by Welch's method with the Hanning window, sampling rate at 200 Hz in a data block of 1 s, administered at a frequency resolution of 1 Hz and with half of the data overlap in each step), similar to our previous study (13 (link), 15 (link), 16 (link)). We calculated the normalized PSD at a specific frequency by measuring the ratio of the PSD of that specific frequency to the sum of the total PSD of 0–50 Hz, and analyzed in theta (4–7 Hz), alpha (8–12 Hz), and beta (13–25 Hz) frequency bands.

Wang T.S., Wang S.S., Wang C.L, & Wong S.B. (2024). Theta/beta ratio in EEG correlated with attentional capacity assessed by Conners Continuous Performance Test in children with ADHD. Frontiers in Psychiatry, 14, 1305397.

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Intracranial ECoG Recordings in Neurological Studies

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The strip or grid electrodes were connected, together with a needle ground electrode inserted subcutaneously in the dorsum of the neck, to a clinical 32-channel amplifier (Neurofax EEG-1200, Nihon Kohden, Japan). The ECoG recording parameters are listed in Supplementary Table 2. Recording was continuous for 2–10 h. Several minute intervals were selected for analysis (when needed after band-stop filtering of 59–61 Hz to reduce powerline noise) as noted below after visual inspection of the entire recording. Recording sampling rate was 1000 Hz, band-pass filtered at 0.5–300 Hz.

Dobariya A., El Ahmadieh T.Y., Good L.B., Hernandez-Reynoso A.G., Jakkamsetti V., Brown R., Dunbar M., Ding K., Luna J., Kallem R.R., Putnam W.C., Shelton J.M., Evers B.M., Azami A., Geramifard N., Cogan S.F., Mickey B, & Pascual J.M. (2022). Recording of pig neuronal activity in the comparative context of the awake human brain. Scientific Reports, 12, 15503.

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EEG Recording Protocol for Neuroscience Research

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EEG recordings were acquired according to the recommendations of the American Society for Electroencephalography using the standard 10–20 system of electrode placement,³⁴ and a digital EEG instrument (Neurofax EEG‐1200, Nihon‐Kohden, Tokyo, Japan).
The ipsilateral earlobes were used as a reference for all EEG electrodes. Ag/AgCl electrodes were used, and the impedance was maintained below 5 kΩ. The EEG data were filtered (time constant, 0.16 s; high‐frequency filter, 100 Hz) and digitized (sampling rate, 500 Hz). Recordings were acquired in a sound‐attenuated room that had subdued lighting, and patients were placed in a semi‐recumbent position with their eyes closed but in a maximally alert state. The alertness of patients was controlled during the recording. If patterns of drowsiness appeared in the EEG recordings, subjects were aroused by acoustic stimulation. Detailed information is described in a previous study.¹⁷

Ozaki T., Mikami K., Toyomaki A., Hashimoto N., Ito Y.M, & Kusumi I. (2023). Assessment of electroencephalography modification by antipsychotic drugs in patients with schizophrenia spectrum disorders using frontier orbital theory: A preliminary study. Neuropsychopharmacology Reports, 43(2), 177-187.

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EEG Changes Before and After ECT

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The participants underwent EEG before (TP1) and after (TP2) a series of ECT. The first recording was performed between admission and the first ECT, and the second recording was done within 1 week after the last ECT. EEG data was obtained and digitalized on Nihon Kohden EEG machines (Neurofax EEG-1200) by trained technicians at Keio University Hospital. Five minutes of resting EEG was recorded under eyes-closed conditions from 19 scalp locations according to the international 10/20 system (Fp1/2, F3/4, C3/4, P3/4, O1/2, F7/8, T3/4, T5/6, Fz, Cz, Pz) referenced to linked ear lobes (A1 and A2). Impedances were kept below 5 kΩ. Data were collected digitally with a sampling rate of 500 Hz. Simultaneous video recordings were used to check each segment for movements and to exclude these segments.

Takamiya A., Hirano J., Yamagata B., Takei S., Kishimoto T, & Mimura M. (2019). Electroconvulsive Therapy Modulates Resting-State EEG Oscillatory Pattern and Phase Synchronization in Nodes of the Default Mode Network in Patients With Depressive Disorder. Frontiers in Human Neuroscience, 13, 1.

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