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Chondroitin sulfate a sodium salt cs

Manufactured by Merck Group
Sourced in United States

Chondroitin sulfate A sodium salt (CS) is a sulfated glycosaminoglycan commonly found in the extracellular matrix of various connective tissues. It is a key structural component of cartilage and is involved in maintaining the mechanical properties of the tissue.

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2 protocols using chondroitin sulfate a sodium salt cs

1

Chondroitin Sulfate-Based Biomaterial Synthesis

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Chondroitin sulfate A sodium salt (CS) (Type A 70%, balanced with Type C, from bovine trachea), glycidyl methacrylate (GMA), poly(ethylene glycol) methyl ether (MPEG, Mn = 2,000), ε-caprolactone (ε-CL), acryloyl chloride (AC), triethylamine (TEA) and ammonium persulfate (98%) (APS) were purchased from Sigma-Aldrich Company, USA. 2-(4-Amidinophenyl)-6-indolecarbamidine dihydrochloride (DAPI) was obtained from Roche, USA. The rest of the reagents were used as received. All the reagents were analytic grade quality.
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2

PLGA Scaffold Fabrication Protocol

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Faster degrading poly(D,L-lactic-co-glycolic-acid) (PLGA) (50:50 lactic acid:glycolic acid, ester end group, Mw = 106 kDa) of intrinsic viscosity 0.6-0.8 dL/g, and slower degrading PLGA (75:25 lactic acid:glycolic acid, ester end group, Mw = 112 kDa) of intrinsic viscosity 0.6-0.8 dL/g were purchased from Evonik Industries (Birmingham, AL). The raw materials were chondroitin sulfate A sodium salt (CS) and β-tricalcium phosphate (TCP), which were obtained from Sigma (St. Louis, MO). All reagents and organic solvents utilized were of cell culture or ACS grade.
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