Stealthmerge image registration

Manufactured by Medtronic

Sourced in United States

StealthMerge Image Registration is a software tool designed to assist medical professionals in aligning and integrating medical images from different modalities, such as CT, MRI, and PET scans. The core function of this product is to enable the accurate registration and fusion of these diverse image sets, providing healthcare providers with a comprehensive and integrated view of a patient's anatomical information.

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Lab products found in correlation

Stealthstation s7, by Medtronic (2 mentions)

2 protocols using stealthmerge image registration

Mapping Glioma Molecular Profiles

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⁶⁸Ga-Pentixafor-PET/CT and T1-weighted rapid three-dimensional gradient-echo technique (MP-RAGE) MR images were transferred to a neuro-navigation system (Stealth Station S7, Medtronic Navigation, Louisville, USA) and combined in image fusion planning (StealthMerge Image Registration, Medtronic Navigation, Louisville, USA). During surgery of the gliomas, neuro-navigated biopsy specimens were obtained from areas with ⁶⁸Ga-Pentixafor uptake by three experienced neurosurgeons (M.L.; T.L.; A.F.K). In 5 cases, separate tumor samples with high and low/no tracer accumulation were biopsied, respectively.

Lapa C., Lückerath K., Kleinlein I., Monoranu C.M., Linsenmann T., Kessler A.F., Rudelius M., Kropf S., Buck A.K., Ernestus R.I., Wester H.J., Löhr M, & Herrmann K. (2016). 68Ga-Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression in Glioblastoma. Theranostics, 6(3), 428-434.

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Correlating Glioma Infiltration with DOTATATE PET

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In three patients (#2, 3 and 15), ⁶⁸Ga-DOTATATE-PET/CT and MR images were transferred to a neuronavigation system (Stealth Station S7, Medtronic Navigation, Louisville, USA) and combined in image fusion planning (StealthMerge Image Registration, Medtronic Navigation, Louisville, USA). During surgery of the gliomas, neuronavigated biopsy specimens were separately obtained from areas with visually different ⁶⁸Ga-DOTATATE-uptake by an experienced neurosurgeon (M.L.) 3 samples out of areas with high, moderate and/or low ⁶⁸Ga-DOTATATE uptake were acquired from each patient and checked for macrophage infiltration. A total of nine samples (3 per patient) were examined. After histological processing, the percentage of microglia and macrophages was visually assessed, calculated and graded using the following scale: 0–20%, 20–50% and >50% related to the total number of cells assessed for SSTR2A staining. For each patient, 3 different tumor areas with a diameter of 5 to 10 mm were examined and correlated with the ⁶⁸Ga-DOTATATE uptake level (SUV_max).

Lapa C., Linsenmann T., Lückerath K., Samnick S., Herrmann K., Stoffer C., Ernestus R.I., Buck A.K., Löhr M, & Monoranu C.M. (2015). Tumor-Associated Macrophages in Glioblastoma Multiforme—A Suitable Target for Somatostatin Receptor-Based Imaging and Therapy?. PLoS ONE, 10(3), e0122269.

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