Disodium hydrogen phosphate

Tetracycline hydrochloride (TET), chlorTetracycline hydrochloride (CTC) doxycycline hydrochloride (DOX), oxyTetracycline hydrochloride (OTC), hexaammineruthenium(II) chloride, hexaammineruthenium(III) chloride, graphene oxide (GO, ref:763705) and trichloroacetic acid were purchased from Sigma-Aldrich (https://www.sigmaaldrich.com). Disodium hydrogen phosphate and sodium dihydrogen phosphate were purchased from Panreac (http://www.panreac.com). Ascorbic acid was purchased from Fluka Chemie (via Sigma-Aldrich, Darmstadt, Germany). All solutions were prepared in Milli-Q water (https://www.merckmillipore.com). Skim milk was acquired in a Spanish market. River water samples were collected from Henares River (Spain).

K₄Fe(CN)₆·3H₂O, K₃Fe(CN)₆, Ru(NH₃)₆Cl₃, N,N-dimethylformamide (DMF), alpha-1-acid glycoprotein (AGP) (≥ 99%), transferrin (≥ 98%), human serum (certified reference material, ERM-DA470K/IFCC), potassium osmate (VI) dihydrate, N,N,N′,N′-tetramethylenediamine (TEMED), potassium nitrate (≥ 98%), uric acid, dopamine, l-tyrosine, and cellulose microcrystalline powder (20 µm) were purchased from Sigma–Aldrich (Darmstadt, Germany). Hydrochloric acid (37%), sulfuric acid (95–98%), sodium chloride, disodium hydrogen phosphate, and sodium dihydrogen phosphate were purchased from PanReac (Barcelona, Spain).
SWCNTs were acquired from Carbon Solutions Inc. (type P2-SWNT, Riverside, CA, USA). These correspond to a purified material following a non-specified non-oxidative process.
For the synthesis of CNC and characterization of CNC/SW hybrids, ultrapure water was obtained from a Siemens Ultraclear device, with a conductivity of 0.055 μS cm⁻¹. For the analytical studies, all aqueous solutions were prepared in Milli-Q water (Merck Millipore, Darmstadt, Germany).

Nifedipine (>98%, NFD) was obtained from Kemprotec Limited (Carnforth, UK), while Eudragit L-100-55 (methacrylic acid-ethyl acrylate copolymer 1:1) was donated by Evonik Rohm GmbH (Essen, Germany). Cyclic olefin copolymer filaments (transparent, 1.75 mm diameter size) (COC) were obtained from Creamelt^® 3D Printing Materials (Rapperswil-Jona, Switzerland) and UV polymerizable resin (405 nm) was obtained from Anycubic^® (Shenzhen, China). Deoxycholic acid sodium salt (>98%) was obtained from Fluka Biochemica (Cleveland, OH, USA). Solvents such as methanol, ethanol, dimethylsulfoxide, and other chemicals such as sodium chloride, potassium chloride, disodium hydrogen phosphate, potassium dihydrogen phosphate, and polysorbate 80 (Tween 80) were all of ACS grade or above and were purchased from Panreac (Barcelona, Spain). Cellulose acetate dialysis membranes with a molecular weight cut-off of 3500 Da were purchased from Medicell Ltd. (London, UK). The Anycubic Photon Mono X (LCD-based SLA printer, 405 nm light source, 0.05 mm 3840 × 2400 XY resolution, 0.01 mm Z resolution, 192 × 120 × 245 mm build volume) and Anycubic Mega Zero (FDM printer, 0.1 mm layer resolution 0.125 mm XY resolution, 0.4 mm nozzle diameter) were obtained from Anycubic^® (Shenzhen, China).