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2 protocols using 4 cyano 4 thiobenzoylthio pentanoicacid

1

Synthesis and Characterization of Polymer-Coated Titanium Alloy

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Azobisisobutyronitrile
(AIBN; molar mass (M): 164.21 g mol–1), 4-cyano-4-(thiobenzoylthio)pentanoic
acid (M: 279.38 g mol–1), methacrylic acid (MAA;
M: 86.09 g mol–1), methyl methacrylate (MMA; M:
100.12 g mol–1), aluminum oxide (Al2O3), dopamine hydrochloride (M: 189.64 g mol–1), tris(hydroxymethyl)aminomethane buffer (M: 121.14 g mol–1), potassium hydroxide (KOH), and deuterated dimethyl sulfoxide (DMSO)-d6 were purchased from Sigma-Aldrich (Zwijndrecht,
the Netherlands). Titanium grade 5 wires (Ti6Al4V) with a 1 mm diameter
and an average RMS surface roughness value of 2 μm were purchased
from SELFAN Fine + Metal GmbH (Köln, Germany). Altuglas PMMA
granules were acquired from Resinex (Deventer, the Netherlands). Toluene,
acetone, 2-propanol, and N,N-dimethylformamide
(DMF) were obtained from VWR (Amsterdam, the Netherlands). All chemicals
were used as received, with the exception of AIBN, which was crystallized
from methanol prior to use.
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2

Synthesis and Characterization of OEGMA-AEMA Copolymers

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Oligo(ethylene glycol) methyl ether methacrylate (OEGMA) (average Mn∼ 300 Da), (2-acetoacetoxy)ethyl methacrylate (AEMA) (95%), 2,2-azobis(2-methylpropionitrile) (AIBN) (≥98%), triethylamine (Et3N) (>99%), 1,4-dioxane (anhydrous, 99.8%), n-hexane (anhydrous, 95%), ethyl acetate (anhydrous, 99.8%), deuterated dimethyl sulphoxide (DMSO-d6) (99.9 atom % D), 4-cyano-4-(thiobenzoylthio)pentanoic acid (≥97%), 4-nitrophenol (≥99%), nitrobenzene (≥99%), 3-(4-nitrophenyl)-1,3-oxazolidin-2-one (95%), chloroform (CHCl3) (≥99%), and deuterated chloroform (CDCl3) (99.8 atom % D) were supplied by Merk (Sigma-Aldrich) (Madrid, Spain). Tetrachloroauric (III) acid trihydrate (99%) was supplied by Thermo Scientific (Eindhoven, The Netherlands). Methanol (MeOH, analytical grade) and tetrahydrofuran (THF, GPC grade) were supplied by Scharlau (Barcelona, Spain). Deionized water was obtained from a Thermo Scientific apparatus (Barnstead TII Pure Water System) (Eindhoven, The Netherlands).
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