Corosolic acid

Manufactured by Phytolab

Sourced in Germany

Corosolic acid is a triterpene compound extracted from the leaves of the Banaba plant (Lagerstroemia speciosa). It is a naturally occurring compound with potential biological activities. The core function of corosolic acid is to serve as a research tool for scientific investigations, without any interpretation or extrapolation of its intended use.

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Lab products found in correlation

Maslinic acid, by Phytolab (2 mentions) Oleanolic acid, by Phytolab (2 mentions) Palmitic acid, by Merck Group (2 mentions) Hyperoside, by Extrasynthese (1 mentions) Betulinic acid, by Phytolab (1 mentions) Hipersolv chromanorm, by Avantor (1 mentions) Analar normapur, by Avantor (1 mentions) Delphinidin 3 o glucoside, by Phytolab (1 mentions) Malvidin 3 o glucoside, by Phytolab (1 mentions) Petunidin 3 o glucoside, by Phytolab (1 mentions) Peonidin 3 o glucoside, by Phytolab (1 mentions) Gpr rectapur, by Avantor (1 mentions) Linoleic acid, by Merck Group (1 mentions) Rutin, by Extrasynthese (1 mentions) Cyanidin 3 o glucoside, by Phytolab (1 mentions) Chlorogenic acid, by Carl Roth (1 mentions) Ursolic acid, by Phytolab (1 mentions) Chenodeoxycholic acid cdca, by Merck Group (1 mentions) Linoleic acid, by Thermo Fisher Scientific (1 mentions) Lithocholic acid lca, by Merck Group (1 mentions)

2 protocols using corosolic acid

Comprehensive Analytical Standards Protocol

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Methanol (MeOH) and hexane (HEX), both AnalaR
Normapur, dichloromethane (DCM) and ethyl acetate (EtOAc), both GPR
Rectapur, and acetonitrile (ACN) HiPerSolv Chromanorm for HPLC–CAD–MS
analysis were obtained from VWR (Vienna, Austria). Formic acid (purity
>98.0%) and conc. ammonia (24%) were purchased from Gatt-Koller
(Absam,
Austria). Water, for extraction and phytochemical analysis, was deionized
and distilled. Betulinic acid (purity 95%), corosolic acid (purity
90%), maslinic acid (purity 89%), oleanolic acid (purity 94%) and
ursolic acid (purity 94%), cyanidin-3-O-sambubioside
(purity 99%), cyanidin-3-O-glucoside (purity 88%),
delphinidin-3-O-glucoside (purity 87%), malvidin-3-O-glucoside (purity 99%), peonidin-3-O-glucoside
(purity 94%), and petunidin-3-O-glucoside (purity
99%) were provided from Phytolab (Vestenbergsgreuth, Germany), hyperoside
(purity 99%), and rutin (purity 99%) from Extrasynthèse (Lyon,
France), and palmitic acid (purity 99%) and linoleic acid (purity
99%) from Sigma-Aldrich (St. Louis, MO).

Waldbauer K., Seiringer G., Sykora C., Dirsch V.M., Zehl M, & Kopp B. (2018). Evaluation of Apricot, Bilberry, and Elderberry Pomace Constituents and Their Potential To Enhance the Endothelial Nitric Oxide Synthase (eNOS) Activity. ACS Omega, 3(9), 10545-10553.

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Quantification of Triterpene Acids

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Maslinic acid, corosolic acid, oleanolic acid, and ursolic acid were obtained from Phytolab (Vestenbergsgreuth, Germany), lithocholic acid (LCA), chenodeoxycholic acid (CDCA), oleic acid, and palmitic acid from Sigma Aldrich (St. Louis, MO, United States), stearic acid and 4-methoxycinnamic acid from Fluka (Buchs, Switzerland), chlorogenic acid from Carl Roth (Karlsruhe, Germany), and linoleic acid from Acros (Geel, Belgium). Eugenol was isolated from clove and the identity and purity tested by ATR-IR spectroscopy. All reference and standard compounds were obtained in a purity of ≥90%. They were dissolved to 1.0 mg/mL in MeOH. The triterpene acids (TTAs) used for the quantification were mixed and diluted to give a standard solution containing 100 μg/mL of each corosolic acid, Maslinic acid, oleanolic acid, and ursolic acid followed by a serial dilution down to 2 μg/mL.

Ladurner A., Zehl M., Grienke U., Hofstadler C., Faur N., Pereira F.C., Berry D., Dirsch V.M, & Rollinger J.M. (2017). Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5. Frontiers in Pharmacology, 8, 468.

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