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2 protocols using ethylenediamine

1

Synthesis of Ruthenium(III) Complexes

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All commercially purchased materials were used as received. Ethylenediamine, guanosine 5′-monophosphate disodium salt and ruthenium(III) chloride hydrate were purchased from Fluorochem Ltd. (Hadfield, UK). L-histidine was purchased from Acros Organics (Geel, Belgium). Silver carbonate was purchased from Alfa Aesar (Heysham, UK). Ammonium hexafluorophosphate, citric acid, deuterium chloride (20 wt. % solution in D2O), sodium deuteroxide (40 wt. % solution in D2O), sodium phosphate dibasic heptahydrate, sodium sulfate, trimethylamine and 2,2,2-trifluoroethanesulfonyl chloride were purchased from Fisher Scientific (Loughborough, UK). Dichloromethane, ethanol and methanol were purchased from Honeywell (Morristown, NJ, USA). Diethyl ether was purchased from VWR (Lutterworth, UK). Chloroform-d, dimethylsulfoxide-d6 and deuterium oxide were purchased from Eurisotop (Saint-Aubin, France).
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2

Synthesis and Characterization of Novel Osmium Complexes

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All commercially purchased materials were used as received. Osmium(III) chloride hydrate was purchased from Acros organics. 3-( p -tolyl)propionic acid was purchased from Alfa Aesar. Ammonia was purchased from Energas. Dimethylsulfoxide-d 6 and deuterium oxide were purchased from Eurisotop. 4-Methylcinnamic acid (predominantly trans), lithium, HCl (37 %), N,N -diisopropylethylamine (DIPEA), N , N -dimethylformamide (DMF), silver nitrate, sodium oxalate and sodium sulfate were purchased from Fisher Scientific. Guanosine 5′-monophosphate disodium salt, ruthenium(III) chloride hydrate, O -(benzotriazol-1-yl)-N,N,N',N' -tetramethyluronium tetrafluoroborate (TBTU), di-tert -butyl dicarbonate, ethylenediamine and silica gel (60Å 40-63 micron) were purchased from Fluorochem Ltd. Acetone, ethanol, ethyl acetate, dichloromethane (DCM), dimethyl sulfoxide (DMSO), methanol and 2-propanol were purchased from Honeywell. Methylamine hydrochloride, 3-( p -tolyl)propanoic acid and 1,3,5-triaza-7-phosphaadamantane (PTA) were purchased from Sigma Aldrich. Diethyl ether was purchased from VWR.
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