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Echelon 10

Manufactured by Medtronic
Sourced in United States

The Echelon 10 is a laboratory equipment product designed for a variety of applications. It serves as a versatile platform for conducting various analytical and experimental procedures. The core function of the Echelon 10 is to provide a controlled and reliable environment for research and testing activities.

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6 protocols using echelon 10

1

Endovascular Treatment for Intracranial Stenting

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Endovascular treatment was performed on the angiographic system (Artis zeego, Siemens AG, Healthineers, Forchheim, Germany). After general anesthesia, a long femoral sheath and a 6F guiding catheter (Johnson & Johnson, NJ, USA) were deployed, then the microcatheter was introduced at the target location. Treatment planning was carefully determined by three-dimensional (3D) rotational angiography.
Leo plus (Balt Extrusion, Montmorency, France) has its own microcatheter, and the Leo plus baby stent was delivered via a 0.017″ microcatheter or Echelon 10 (Medtronic, Irvine, CA, USA). Tirofiban hydrochloride (Yuanda Pharmaceutical Co. LTD, China) was used for acute thrombus within the stent, and if the stent was poorly opened, microcatheter massage of the stent or balloon dilatation was considered. Intracranial hemorrhage was routinely ruled out after the procedure by flat detector computed tomography (FD-CT).
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2

Endovascular Treatment of Intracranial Aneurysms

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The endovascular treatment was performed for patients under general anesthesia. A bolus of 50 IU/kg of heparin was given and routinely administered during the procedure to achieve an activated clotting time of >250 s. The femoral artery was introduced with a 6 Fr short sheath (Terumo, Japan), and a 6 Fr guiding catheter (Envoy; Johnson & Johnson, USA) was advanced to the proximal arterial lesion to establish a pathway. The structure of the lesion was assessed by 3D digital subtraction angiography using a standard biplane machine (Artis Zee Biplane; Siemens, Germany). Then, a microcatheter (Headway; Microvention, CA, USA) was placed in the parent artery to deliver the LVIS stent. The decision between selecting the LVIS or LVIS Jr. is contingent upon a multifactorial assessment, taking into account the diameter of the parent artery as well as the clinical experience of the surgeon involved. The structural characteristics of these two variations are summarized in Table 1. Another microcatheter (Echelon-10; Medtronic, USA) was carefully introduced into the aneurysm sac. The semi-jailing technique (21 (link)) was applied to assist in the coiling packing density. The stent was fully deployed following the completion of the embolization procedure.
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3

Cavernous Sinus Fistula Embolization

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The right femoral artery was punctured, a 5/6F artery sheath was implanted, and the proper blood-supplying artery was chosen based on the diameter, length, tortuosity, and type of collateral branch determined using super-selective angiography. An Echelon™-10 or Marathon™ microcatheter (Medtronic, USA) was used to super-selectively approach the cavernous sinus fistula with the aid of the microguidewire, and the angioarchitecture was revealed through super-selective angiography, thus avoiding dangerous anastomoses. Spring coil embolization was performed on the fistula to slow down the blood flow, when necessary. Subsequently, Onyx™ LES (Medtronic, USA) was slowly injected using the roadmap-bolus-diffusion-pause-roadmap-bolus method. Angiography was repetitively conducted during the Onyx injection to observe the status of the cavernous sinus embolization. The surgery was terminated once the fistula disappeared.
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4

Microcatheter X-ray Absorption and Thermal Shaping

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Eight types of microcatheters, always available in our angiography room, were simultaneously imaged with cone-beam CT in their boxes to measure X-ray absorption values. Products included Excelsior SL-10 (Stryker, Kalamazoo, Michigan, United States), XT-17 (Stryker), Excelsior 1018 (Stryker), Headway DUO (Terumo, Tokyo, Japan), Headway 17 (Terumo), Headway 21 (Terumo), Phenom 17 (Medtronic, Irvine, California, United States), and Echelon 10 (Medtronic). Next, five microcatheters (Excelsior SL-10, Excelsior 1018, Headway DUO, Headway 17, and Phenom 17) that were available for this study were thermally formed with a hot-air gun, and the following experiments were performed.
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5

Neuroendovascular Aneurysm Treatment Techniques

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All neuro-endovascular treatments were performed under general anaesthesia. The femoral artery was accessed through a 6F or 8F short sheath introducer. A 6F guide catheter (Envoy, Cordis, Bridgewater, New Jersey, USA) or a 6F long sheath (Neuron Max 088 Penumbra, USA) was placed proximally in the internal carotid or vertebral artery. The aneurysm was catheterized with a 0.0165” or 0.017” microcatheter (Excelsior SL-10, Stryker neurovascular, Kalamazoo, MI, USA or Echelon 10, Medtronic Irvine, CA, USA) over a 0.012” or 0.014” neurovascular micro-guidewire to deploy the coils into the aneurysmal sac. In the case of SAC, the parent vessel was first catheterized with a suitable microcatheter over a 0.014” neurovascular micro-guidewire to deploy the stent across the aneurysmal neck. Both braided (BR) and laser-cut stents (LC) were used. Final angiograms were performed to evaluate the patency of the parent artery and to assess the aneurysm occlusion rate by using the Raymond-Roy occlusion classification (RROC).4 (link)
Figure 1 shows a representative case illustrating the procedure.
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6

Endovascular Treatment of Intracranial Aneurysms

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Either a 7-Fr guiding catheter (Envoy; DePuy Synthes) or a 6-Fr long sheath (NeuronMax; Penumbra, Inc.) was used to catheterize the internal carotid artery (ICA) or vertebral artery (VA). After performing 3D rotational angiography, a Rebar 18 catheter (Medtronic, Inc.) was navigated into the parent vessel distally to the aneurysm, while an Excelsior SL10 (Stryker Neurovascular), Echelon 10 (Medtronic, Inc.), or Echelon 14 (Medtronic, Inc.) microcatheter was positioned inside the aneurysm. The diameter of the parent artery determined the size of the Cascade net used. After the device was fully unsheathed and the braid expanded, the Cascade net was moved backward slightly and then forward, partially resheathing the net until the operator was fully satisfied with the device location and the best neck coverage possible.
Next, the first coil was inserted into the aneurysm with the microcatheter inside the sac. The Cascade net was deflated before detachment of the last coil to confirm stability of the coils inside the aneurysm. Finally, the Cascade net was retrieved after removal of the intrasaccular microcatheter.
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