T1-weighted MR images were acquired on one of two MR imaging systems: MR images acquired in 2009 and earlier (49%) were acquired on a 1.5T GE Signa scanner whereas later scans (51%) were acquired on a 3.0T Siemens Magnetom Trio. Participants scanned on the 1.5T GE Signa scanner were positioned in a standard head coil and a brief scout T1-weighted image was obtained. A volumetric spoiled gradient recalled (SPGR) sequence with parameters optimized for contrast among gray matter, white matter, and CSF were acquired in the coronal plane (TE/TR = 5/25, flip angle = 40°, NEX = 1, slice thickness = 1.5 mm/0 mm interslice). MR images acquired on the 3T Siemens Magnetom Trio used a magnetization prepared rapid acquisition gradient echo (MPRAGE) sequence (TI/TE/TR = 900/2.98/2300 ms, flip angle = 9°, slice thickness = 1.2 mm, matrix size = 160 × 240 × 256).
Magnetom trio
Manufactured by Siemens
Sourced in Germany, United States, United Kingdom
The Magnetom Trio is a magnetic resonance imaging (MRI) system manufactured by Siemens. It is designed to produce high-quality images of the body's internal structures. The Magnetom Trio uses a powerful superconducting magnet to generate a strong magnetic field, which, in combination with radio waves, allows for the detailed visualization of the body's anatomy and physiology.
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Lab products found in correlation
12 channel head coil, by Siemens (17 mentions)
32 channel head coil, by Siemens (12 mentions)
Gadovist, by Bayer (11 mentions)
Magnetom avanto, by Siemens (9 mentions)
Magnetom verio, by Siemens (9 mentions)
Prisma, by Siemens (8 mentions)
Magnevist, by Bayer (8 mentions)
Magnetom skyra, by Siemens (7 mentions)
Magnetom prisma, by Siemens (6 mentions)
Signa hdx, by GE Healthcare (6 mentions)
Magnetom sonata, by Siemens (6 mentions)
Signa hdxt, by GE Healthcare (5 mentions)
Dotarem, by Guerbet (5 mentions)
Prisma fit, by Siemens (5 mentions)
Primovist, by Bayer (5 mentions)
Multihance, by Bracco (4 mentions)
Magnetom aera, by Siemens (4 mentions)
Matlab, by MathWorks (4 mentions)
Achieva, by Philips (4 mentions)
Signa 750, by GE Healthcare (4 mentions)
803 protocols using magnetom trio
1
Multimodal MRI Acquisition Protocol
2
Structural and Functional MRI Acquisition Protocol
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We acquired structural and functional imaging data on a 3T MRI scanner (Siemens Magnetom Trio; Siemens Medical Solutions, Erlangen, Germany) with a 12‐channel radio frequency head coil for signal reception. Structural 3D‐T1‐weighted (modified driven equilibrium Fourier transform pulse sequence; MDEFT) 31 images for each subject were obtained, providing 176 sagittal slices with 256 × 256 matrix points with a non‐cubic field of view (FOV) of 256 mm, yielding a nominal isotopic resolution of 1 mm³ (i.e., 1 × 1 × 1 mm). Additional scan parameters for the anatomical data were 7.92 ms repetition time (TR), 2.48 ms echo time (TE), and a flip angle of 16° (FA). Furthermore, we obtained 110 functional images [pseudo continuous arterial spin labeling (pCASL) sequence] 32 , 33 . Scanning parameters for the functional images were as follows: 20 slices (in ascending order) with 64 × 64 matrix points with a non‐cubic FOV of 230 mm, yielding a nominal isotopic resolution of 4.27 mm³ (i.e., 3.6 × 3.6 × 6 mm), TR of 4000 ms, TE of 18 ms, and a FA of 25°.
3
Multimodal MRI Acquisition Protocol for Osteoarthritis
4
Multi-site MRI T2 Relaxometry Protocol
5
Multimodal MRI Acquisition Protocol
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Functional and structural data was acquired on a SIEMENS MAGNETOM Prisma (3 Tesla magnetic resonance imaging scanner (Siemens, Germany)). Functional images were collected with a 20-channel head coil using a gradient echo EPI (echo planar imaging) sequence (TR = 2790 ms, TE = 30 ms, flip angle = 90°, 42 slices, whole brain coverage; slice thickness = 2 mm; interslice gap = 1 mm; in-plane resolution = 3 × 3 mm).
A structural image was acquired using a 32-channel head coil and a T1-weighted 3D magnetization-prepared rapid gradient echo (MPRAGE) sequence (TR = 2300 ms; TE = 2.98 ms; TI = 900 ms; flip angle = 9°; FOV = 256 mm × 240 mm; voxel size = 1 mm3 (isotropic resolution) 176 sagittal slices). This was done only for participants (n = 10) for whom no data was available from previous studies conducted at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig. We accessed MPRAGE images available in the institute's data bank, which had been acquired also with a 32-channel coil and with the exact same acquisition parameters on 3 Tesla MRI scanners (SIEMENS MAGNETOM Trio, Verio and Prisma (Siemens, Germany).
A structural image was acquired using a 32-channel head coil and a T1-weighted 3D magnetization-prepared rapid gradient echo (MPRAGE) sequence (TR = 2300 ms; TE = 2.98 ms; TI = 900 ms; flip angle = 9°; FOV = 256 mm × 240 mm; voxel size = 1 mm3 (isotropic resolution) 176 sagittal slices). This was done only for participants (n = 10) for whom no data was available from previous studies conducted at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig. We accessed MPRAGE images available in the institute's data bank, which had been acquired also with a 32-channel coil and with the exact same acquisition parameters on 3 Tesla MRI scanners (SIEMENS MAGNETOM Trio, Verio and Prisma (Siemens, Germany).
6
High-resolution 3T MRI and DTI Acquisition
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MRI-scans were acquired on a 3 Tesla MRI-scanner (Siemens Magnetom Trio; Siemens Medical Solutions, Erlangen, Germany) with a 12-channel radio frequency headcoil for signal reception.
3D-T1-weighted (Modified Driven Equilibrium Fourier Transform Pulse Sequence; MDEFT) images for each subject have been obtained, resulting in 176 sagittal slices with 256 × 256 matrix points with a non-cubic field of view (FOV) of 256 mm, yielding a nominal isotopic resolution of 1 mm3. Further scan parameters were as follows: Repetition time (TR) = 7.92 ms, echo time (TE) = 2.48 ms and flip angle = 16°
For DTI measurements, a spin echo planar imaging (EPI) sequence (59 slices, FOV = 256 × 256 mm2, sampled on a 128 × 128 matrix, slice thickness = 2 mm, gap between slices = 0 mm, resulting in 2 mm3 isotopic voxel resolution, TR/TE = 8000/92 ms) covering the whole brain (40 mT/m gradient, 6/8 partial Fourier, GRAPPA factor 2, bandwidth 1346 Hz/Px) was used. Diffusion-weighted images (DWI) were positioned in the axial plane parallel to the AC-PC line. Diffusion encoding gradients (b-value = 1300s/mm2) were applied along 42 directions. In addition, four non-diffusion weighted scans (b-value = 0 s/mm2) were collected. We used a balanced and rotationally invariant diffusion-encoding scheme over the unit sphere to generate the DTI data. Acquisition time was 6 min.
3D-T1-weighted (Modified Driven Equilibrium Fourier Transform Pulse Sequence; MDEFT) images for each subject have been obtained, resulting in 176 sagittal slices with 256 × 256 matrix points with a non-cubic field of view (FOV) of 256 mm, yielding a nominal isotopic resolution of 1 mm3. Further scan parameters were as follows: Repetition time (TR) = 7.92 ms, echo time (TE) = 2.48 ms and flip angle = 16°
For DTI measurements, a spin echo planar imaging (EPI) sequence (59 slices, FOV = 256 × 256 mm2, sampled on a 128 × 128 matrix, slice thickness = 2 mm, gap between slices = 0 mm, resulting in 2 mm3 isotopic voxel resolution, TR/TE = 8000/92 ms) covering the whole brain (40 mT/m gradient, 6/8 partial Fourier, GRAPPA factor 2, bandwidth 1346 Hz/Px) was used. Diffusion-weighted images (DWI) were positioned in the axial plane parallel to the AC-PC line. Diffusion encoding gradients (b-value = 1300s/mm2) were applied along 42 directions. In addition, four non-diffusion weighted scans (b-value = 0 s/mm2) were collected. We used a balanced and rotationally invariant diffusion-encoding scheme over the unit sphere to generate the DTI data. Acquisition time was 6 min.
7
3T MRI T2 Relaxation Time Mapping
8
MRI Contrast Evaluation of Nanoparticles
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In vitro MRI was carried out using box analysis to compare the contrast achieved with the nanoparticle suspension with that of Magnevist® (Gd-DTPA complex with meglumine) solution. A calibration was achieved by diluting Magnevist® to 0.01–2.5 mg∙mL−1 concentration. MR imaging was performed on a 3.0-T scanner (Siemens Magnetom Trio, Siemens Medical Solutions, Erlangen, Germany). The measurement conditions were T1-weighted 3D gradient echo sequences (fast low-angle shot) with the following parameters: TE (echo time) = 3.31 ms, TR (repetition time) = 8.67 ms, field of view = 100 × 78 mm, matrix acquisition = 640 × 480, slice thickness = 0.3 mm, flip angle = 16°, fat suppression = fat saturated, and bandwidth = 180 Hz/Px.
9
Hepatocellular Carcinogenesis in Bitransgenic Mice
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Homozygous metallothionein/TGFα and albumin/c-myc single transgenic mice in CD13B6CBA background were crossed to generate the male TGFα/c-myc bitransgenic mice, as previously described [20 (link),21 (link)]. Hepatocarcinogenesis was accelerated by giving the mice ZnCl2 (via the drinking water) to induce the expression of TGFα. The animals were inspected every 2 to 3 days. To detect and monitor the endogenously formed HCCs in the TGFα/c-myc mice, gadoxetic acid (Gd-EOB-DTPA)-enhanced MRI was performed on a 3T MRI scanner (Siemens Magnetom Trio, Siemens Medical Solutions) as described recently [12 (link),21 (link),22 (link)]. Mice with HCC as identified by Gd-EOB-DTPA-enhanced MRI were used in the subsequent experiments.
10
Comprehensive 3T MRI Knee Imaging Protocol
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