Horizon a system

Manufactured by Hologic

Sourced in United States

The Hologic Horizon/A system is a laboratory equipment product designed for clinical diagnostic applications. It is a fully automated platform that performs sample processing, analysis, and reporting of results. The Horizon/A system is capable of handling a variety of sample types and can be used for a range of in vitro diagnostic tests. The specific details and intended use of the product are not provided in this response.

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Lab products found in correlation

Discovery a system, by Hologic (3 mentions) Discovery a, by Hologic (2 mentions) Whole body phantom, by Hologic (1 mentions) Apex version 5, by Hologic (1 mentions)

Close spelling variants of this product

Horizon A DXA System Horizon A

6 protocols using horizon a system

Dual-Energy X-Ray Absorptiometry and Anthropometry

Cited 1 time

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DXA and anthropometric measures were collected using an adaptation of the protocol described by Ng et al. (26 (link)). In the current study, each participant underwent 2 whole-body DXA scans with repositioning on either a Hologic Horizon/A system at UCSF or a Hologic Discovery/A system at PBRC and at UHCC (Hologic Inc.). Results of the 2 whole-body DXA scans were averaged. Participants were scanned according to the manufacturer's guidelines. All DXA scans were centrally analyzed at UHCC by a single certified technologist using Hologic Apex 5.5 software. Output from DXA included regional and whole-body percentage fat mass, lean soft tissue mass, and mean VAT and SAT for L1–L5. DXA cross-calibration phantoms were circulated between all sites, and calibration equations were derived to remove systematic bias in all bone and soft tissue results.

Panizza C.E., Wong M.C., Kelly N., Liu Y.E., Shvetsov Y.B., Lowe D.A., Weiss E.J., Heymsfield S.B., Kennedy S., Boushey C.J., Maskarinec G, & Shepherd J.A. (2020). Diet Quality and Visceral Adiposity among a Multiethnic Population of Young, Middle, and Older Aged Adults. Current Developments in Nutrition, 4(6), nzaa090.

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Dual-Scan DXA Body Composition Analysis

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As part of the data acquisition procedure for Shape Up, we captured two whole-body DXA scans, with body repositioning between scans, on either a Hologic Horizon/A system (UCSF) or a Discovery/A system (PBRC and UHCC) (Hologic Inc., Marlborough, MA, USA) for each participant. Participants were positioned and scanned according to each manufacturer’s guidelines. All DXA scans were analyzed at UHCC by a single certified technologist using Hologic Apex version 5.6 with the National Health and Nutrition Examination Survey (NHANES) Body Composition Analysis calibration option disabled. DXA systems quality control was performed by monitoring the weekly values of the Hologic Whole Body Phantom. Cross calibration was checked between sites using a whole-body phantom scanned at each site. No cross-calibration adjustments were needed. ^{9 (link)} Body composition measurements from DXA included total and regional (trunk, arms, legs) measures of total fat mass and fat free (lean) mass (FFM). Percent fat (% fat) is represented as fat mass divided by total mass.

Tian I.Y., Ng B.K., Wong M.C., Kennedy S., Hwaung P., Kelly N., Liu E., Garber A.K., Curless B., Heymsfield S.B, & Shepherd J.A. (2020). Predicting 3D Body Shape and Body Composition from Conventional 2D Photography. Medical physics, 47(12), 6232-6245.

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Evaluating Body Composition Using DXA

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Participants received two whole-body DXA scans with repositioning on either a Hologic Horizon/A system at UCSF or a Discovery/A system at PBRC or UHCC (Hologic Inc., Marlborough, MA, USA). Scans were taken according to International Society for Clinical Densitometry guidelines (25 (link)). DXA cross-calibration phantoms were circulated between all sites and calibration equations were derived to remove systematic bias in all bone and soft tissue results. All DXA scans were centrally analyzed by a single certified technologist using Hologic Apex version 5.6 with the NHANES Body Composition Analysis calibration option disabled. The output from the DXA scan included regional and whole-body composition.

Wong M.C., Ng B.K., Tian I., Sobhiyeh S., Pagano I., Dechenaud M., Kennedy S.F., Liu Y.E., Kelly N., Chow D., Garber A.K., Maskarinec G., Pujades S., Black M.J., Curless B., Heymsfield S.B, & Shepherd J.A. (2021). A Pose Independent Method for Accurate and Precise Body Composition from 3D Optical Scans. Obesity (Silver Spring, Md.), 29(11), 1835-1847.

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Whole-Body DXA Scan Protocol

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Whole-body DXA scans were performed using either the Hologic Discovery A at UHCC or Horizon A system at PBRC (Hologic Inc., Malborough, MA, USA) according to the manufacturer’s guidelines. Both systems were calibrated according to standard Hologic procedures (19 (link)) and DXA cross-calibration phantoms scanned at both sites. All completed scans were evaluated at (UHCC) using Hologic Apex software version 5.6 (Hologic, Inc., Marlborough, MA, USA) with the NHANES Body Composition Analysis (BCA) calibration feature disabled. DXA results comprised a number of body composition estimates including whole body percent fat.

Kennedy S., Hwaung P., Kelly N., Liu Y.E., Sobhiyeh S., Heo M., Shepherd J.A, & Heymsfield S.B. (2019). Optical Imaging Technology for Body Size and Shape Analysis: Evaluation of a System Designed for Personal Use. European journal of clinical nutrition, 74(6), 920-929.

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Whole-Body DXA Scan Protocol

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Whole-Body DXA Scan Protocol

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Participants completed one whole‐body dual energy X‐ray absorptiometry (DXA) scan on a Hologic Discovery/A or Horizon/A system (Hologic Inc.). As described in detail previously,¹⁹ DXA scans were all centrally analyzed at UHCC by a trained technologist using Hologic APEX version 5.6 with the (NHANES) Body Composition Analysis calibration option disabled. DXA cross‐calibration phantoms were circulated between all sites and calibration equations derived to remove systematic bias in all bone and soft tissue results. Among other measures, total and percent body fat were derived.

Maskarinec G., Garber A.K., Wong M.C., Kelly N., Kazemi L., Buchthal S.D., Fearnbach N., Heymsfield S.B, & Shepherd J.A. (2020). Predictors of liver fat among children and adolescents from five different ethnic groups. Obesity Science & Practice, 7(1), 53-62.

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