Infinium chips

Manufactured by Illumina

Sourced in United States

Infinium chips are high-density microarray products developed by Illumina for large-scale genomic analysis. They enable simultaneous interrogation of thousands to millions of genetic variants across the human genome. The chips are designed to provide comprehensive coverage and reliable genotyping performance.

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Lab products found in correlation

Beadstation 500g, by Illumina (2 mentions) Genomestudio genotyping analysis module v1, by Illumina (2 mentions)

Spelling variants of this product

Infinium Human Exome Bead Chip Version 1.1 (4 citations) Infinium HumanHap550 genotyping chip (4 citations) Infinium Human610-Quad Bead Chip (4 citations) Infinium OmniExpress v1.1 chip (4 citations) Infinium EPIC 850K chip (3 citations) Infinium methylation 450 k bead chip array (3 citations) 60K chicken Infinium iSelect chip (3 citations) Infinium II HumanHap550 SNP chips (2 citations) Infinium OmniExpressExome-8v1-6_A1 chips (2 citations) Infinium Methylation Bead Chip (2 citations)

3 protocols using infinium chips

SNP Genotyping of DH Populations

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Example 3

The three DH populations, YSC, YDN, and TN, were genotyped with 12,000 SNP markers developed at DAS on two Illumina Infinium chips on the BeadStation 500 G per manufacturer's protocol (Illumina, San Diego, Calif.). Genotypic data was analyzed using the GenomeStudio Genotyping Analysis Module v1.8.4 (Illumina, San Diego, Calif.), which converts fluorescent signals for each SNP into A and B signals whose values reflect the relative abundance of arbitrarily assigned A and B alleles. Signal is converted into polar coordinates, using the Manhattan distance metric for the intensity R, and with Theta∈[0,1] representing angle ∈[0,90] degrees. Each marker is clustered in Cartesian coordinates, and the genotypes {AA, AB, BB} are assigned to samples in clusters close to Theta-{0, ½, 1}.

US11713490B2. Marker assisted selection of traits for producing meal from Brassica napus (2023-08-01). Corteva Agriscience LLC [US]. Inventors: Shunxue Tang [US], Van L. Ripley [CA], Thomas G. Patterson [US], Michelle Wiggins [US], Joshua A. Flook [US], Cherie Ochsenfeld [US], Daniel Garcia [US], Syed Masood Rizvi [CA], Ryan Preuss [US], Donna Carolynn Knievel [CA], Zoe Christina Ehlert [CA], Steve Rounsley [US], Muhammad Tahir [CA].

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SNP Genotyping of DH Populations

Check if the same lab product or an alternative is used in the 5 most similar protocols

Example 3

The three DH populations, YSC, YDN, and TN, were genotyped with 12,000 SNP markers developed at DAS on two Illumina Infinium chips on the BeadStation 500 G per manufacturer's protocol (Illumina, San Diego, Calif.). Genotypic data was analyzed using the GenomeStudio Genotyping Analysis Module v1.8.4 (Illumina, San Diego, Calif.), which converts fluorescent signals for each SNP into A and B signals whose values reflect the relative abundance of arbitrarily assigned A and B alleles. Signal is converted into polar coordinates, using the Manhattan distance metric for the intensity R, and with Theta∈[0,1] representing angle∈[0,90] degrees. Each marker is clustered in Cartesian coordinates, and the genotypes {AA, AB, BB} are assigned to samples in clusters close to Theta={0, ½, 1}.

US10791692B2. Fine mapping and validation of QTL underlying fiber content and identification of SNP markers for marker assisted selection (2020-10-06). Dow AgroSciences LLC [US]. Inventors: Shunxue Tang [US], Van L. Ripley [CA], Thomas G. Patterson [US], Michelle Wiggins [US], Joshua A. Flook [US], Cherie Ochsenfeld [US], Daniel Garcia [US], Syed Masood Rizvi [CA], Muhammad Tahir [CA], Ryan Preuss [US], Donna Carolynn Knievel [CA], Steve Rounsley [US], Zoe Christina Ehlert [CA].

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Robust Genetic Imputation and QC for GWAS

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Detailed procedures of genotyping for this dataset were reported in a previous publication.⁴⁶ Briefly, DNA were extracted from blood samples and genotyped using Infinium chips (Illumina, San Diego, CA, USA), then imputed using Michigan Imputation Server (https://imputationserer.sph.umich.edu/index.html) following their protocol using 1000G Phase 3 EAS population as reference. Imputed data were cleaned again to keep only SNPs with imputation quality r² > 0.8, MAF >0.05, HWE > 1 E‐6, retaining 4,856,474 SNPs. No duplicated or related subjects were identified (maximum PI_HAT = 0.0537, calculated with PLINK2) (https://www.cog-genomics.org/plink/1.9/).⁴⁷, ⁴⁸ No clear population stratification problem or outlier subjects were found by principal component analysis, most likely because this study only enrolled Han Chinese subjects.

Liu H., Zhao X., Xue G., Chen C., Dong Q., Gao X., Yang L, & Chen C. (2022). TTLL11 gene is associated with sustained attention performance and brain networks: A genome‐wide association study of a healthy Chinese sample. Genes, Brain, and Behavior, 22(1), e12835.

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