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Wild type fvb mice

Manufactured by Charles River Laboratories
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Wild-type FVB mice are a common laboratory mouse strain used for various research applications. They are characterized by their unique physical attributes, including albino coat color and prominent blood vessels in the ears and tail. These mice serve as a standard reference strain and are widely utilized in a range of research areas, such as genetics, immunology, and developmental biology.

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Lab products found in correlation

Fvb tg teto mapt p301l kha jlwsj, by Jackson ImmunoResearch (1 mentions) B6 cg tg camk2a tta 1mmay dboj, by Jackson ImmunoResearch (1 mentions)

Spelling variants of this product

FVB mice (47 citations) Wild-type mice (39 citations) Wild-type FVB/N mice (18 citations) Female wild-type FVB/N mice (2 citations)

3 protocols using wild type fvb mice

1

Wild-type FVB Mouse Study

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All animal procedures were carried out in accordance with the UK Animals (Scientific Procedures) Act 1986 and with the University of Oxford (Clinical Medicine) Ethical Committee approval (P4BEAEBB5, 21 August 2022), or for mice housed at INSERM, according to the guidelines of INSERM and the ethical committee of Alsace, France (CREMEAS). The agreement number was D 67-482-033 at the animal facilities of INSERM U682 and U1109, and mice were kept under pathogen-free conditions in cages providing disposable homes and nesting paper, together with food and water at discretion. Wild-type FVB mice were obtained from Charles River Laboratories.
Gschwandtner M., Gammage A.N., Deligne C., Mies L.F., Domaingo A., Murdamoothoo D., Loustau T., Schwenzer A., Derler R., Carapito R., Koch M., Mörgelin M., Orend G., Kungl A.J, & Midwood K.S. (2023). Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2. International Journal of Molecular Sciences, 24(9), 8365.
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2

Generation and Characterization of Tau Transgenic Mice

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Wild-type FVB mice were obtained from Charles River, UK. rTg4510 tauP301L+ and tauP301L− mice were generated from crossing FVB-Tg(tetO-MAPT*P301L)#Kha/JlwsJ (015815; The Jackson Laboratory) with B6.Cg-Tg(Camk2a-tTA)1Mmay/DboJ (007004; The Jackson Laboratory).
Halliday M., Radford H., Zents K.A., Molloy C., Moreno J.A., Verity N.C., Smith E., Ortori C.A., Barrett D.A., Bushell M, & Mallucci G.R. (2017). Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice. Brain, 140(6), 1768-1783.
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3

Genetic Modeling of Breast Cancer

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Wild-type FVB mice were purchased from Charles River Laboratories, and tenascin-C–knockout mice on an FVB background were generated as described in [18 ]. 2–3-month old females were used for the experiments. MMTV-NeuNT female mice (FVB/NCrl background) with a mutated constitutively active form of rat ErbB2 (NeuNT) expressed under the control of the mouse mammary tumor virus (MMTV) regulatory region were purchased from Jackson Laboratory. All animal procedures were carried out in accordance with the UK Animals (Scientific Procedures) Act 1986 and with the University of Oxford (Clinical Medicine) Ethical Committee approval.
Deligne C., Murdamoothoo D., Gammage A.N., Gschwandtner M., Erne W., Loustau T., Marzeda A.M., Carapito R., Paul N., Velazquez-Quesada I., Mazzier I., Sun Z., Orend G, & Midwood K.S. (2020). Matrix-targeting immunotherapy controls tumor growth and spread by switching macrophage phenotype. Cancer immunology research, 8(3), 368-382.
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