Seeds of S. spinosa were brought from the local market of Sargodha, Pakistan (in May–June) and their taxonomy was verified by a botanist, Dr Hassan Sher from the Department of Botany, University of Swat, Mingora, Pakistan. The methacrylic acid (MAA, monomer; 99.0%), potassium persulfate (KPS, initiator; 99.0%), and N,N-methylenebisacrylamide (MBA, cross-linker; 99.5%) were purchased from Sigma-Aldrich, Germany. Potassium dihydrogen phosphate (KH2PO4; 99.0%), NaOH (98.0%), KCl (99.0%), ethanol (95.0%), and n-hexane (95.0%) were acquired from Riedel-de Haen, Germany. Venlafaxine HCl (United States Pharmacopeia (USP) standard) was used as a model drug for in vitro drug release studies from the synthesized hydrogel carrier. For swelling and drug release studies, the buffers of pH 7.4, 6.8, 4.5, and 1.2 were prepared according to the procedure given in USP. All other reagents and chemical ingredients were of lab-grade. Deionized water (DW) was used during the whole research work.
Potassium dihydrogen phosphate kh2po4
Manufactured by Honeywell
Sourced in Germany
Potassium dihydrogen phosphate (KH2PO4) is a chemical compound that is commonly used in various laboratory applications. It is a crystalline solid that is soluble in water. The primary function of potassium dihydrogen phosphate is to serve as a buffer solution, maintaining a specific pH level in chemical reactions and processes.
Automatically generated - may contain errors
Lab products found in correlation
N n methylenebisacrylamide, by Merck Group (1 mentions)
Sodium hydroxide (naoh), by Honeywell (1 mentions)
Potassium persulfate, by Merck Group (1 mentions)
Potassium chloride (kcl), by Honeywell (1 mentions)
Ethanol, by Honeywell (1 mentions)
N hexane, by Honeywell (1 mentions)
Methacrylic acid maa monomer, by Merck Group (1 mentions)
Direct q 3 uv water purification system, by Merck Group (1 mentions)
Molecular sieves 4, by Merck Group (1 mentions)
Methanol, by Merck Group (1 mentions)
Trifluoroacetic acid, by Merck Group (1 mentions)
Triethylamine, by Merck Group (1 mentions)
Pyridine, by Merck Group (1 mentions)
Dopamine, by Merck Group (1 mentions)
Norepinephrine, by Merck Group (1 mentions)
Epinephrine, by Merck Group (1 mentions)
Potassium hexacyanoferrate 3, by Merck Group (1 mentions)
Copper 2 acetate, by Merck Group (1 mentions)
2 protocols using potassium dihydrogen phosphate kh2po4
1
Hydrogel Carrier Synthesis for Drug Delivery
2
Synthesis and Characterization of Thyroid Hormone Analogues
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All commercial reagents used were of analytical grade and were used without further purification. Triiodothyronine (T 3 ) and thyroxine (T 4 ), potassium hexacyanoferrate (III), potassium 4/20 hexacyanoferrate (II) trihydrate (the pair [Fe(CN) 6 ] 3-/4-), 4-aminobenzoic acid (4-ABA), hydrochloric acid, tert-butyl (4-hydroxyphenethyl)carbamate, (4-(methoxymethoxy)phenyl)boronic acid, copper (II) acetate, pyridine, epinephrine, norepinephrine, dopamine, triethylamine, trifluoroacetic acid and molecular sieves 4 Å were purchased from Sigma-Aldrich, methanol was purchased from Merck. Phosphate buffer solution (PBS), 0.1 mol L -1 , pH 7.4 was prepared with potassium dihydrogen phosphate (KH 2 PO 4 ) and potassium hydrogen phosphate (K 2 HPO 4 ), both from Riedel-de-Haën.
Ultrapure water (resistivity not less than 18.2 Ω cm at 298 K) from a Direct-Q 3UV water purification system (Millipore) was used in all experiments. Thin-layer chromatography (TLC) was carried out on precoated silica gel 60 F254 (Merck) with layer thickness of 0. following the synthetic strategies shown in Fig. 1.
The compounds were obtained in moderate to high yields and fully characterized by magnetic resonance spectroscopy ( 1 HRMN, 13 All RMN spectra are present in the Supporting Information.
Ultrapure water (resistivity not less than 18.2 Ω cm at 298 K) from a Direct-Q 3UV water purification system (Millipore) was used in all experiments. Thin-layer chromatography (TLC) was carried out on precoated silica gel 60 F254 (Merck) with layer thickness of 0. following the synthetic strategies shown in Fig. 1.
The compounds were obtained in moderate to high yields and fully characterized by magnetic resonance spectroscopy ( 1 HRMN, 13 All RMN spectra are present in the Supporting Information.
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