Hlugs180su01

Manufactured by Shanghai Outdo Biotech Co.

Sourced in China

The HLugS180Su01 is a specialized laboratory equipment designed for conducting various scientific experiments and analyses. It serves as a versatile tool for researchers and scientists working in diverse fields. The core function of this equipment is to facilitate the accurate and efficient measurement and analysis of specific parameters or samples. However, without further details on the intended use or specific features, a more detailed description cannot be provided while maintaining an unbiased and factual approach.

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Lab products found in correlation

Hluga180su03, by Shanghai Outdo Biotech Co. (1 mentions) Hluga180su02, by Shanghai Outdo Biotech Co. (1 mentions)

3 protocols using hlugs180su01

Lung Cancer Tissue Profiling

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A human LUSC microarray (HLugS180Su01, 90 cancer tissues from patients, and 90 adjacent paracancerous tissues with IHC staining data for CD8 and PD-L1) or a human LUAD microarray (HLugA180Su03, 92 cancer tissues from patients, and 88 adjacent paracancerous tissues with IHC staining data for PD-L1) was purchased from Shang Hai Outdo Biotech Company.

Ren W., Xu Z., Chang Y., Ju F., Wu H., Liang Z., Zhao M., Wang N., Lin Y., Xu C., Chen S., Rao Y., Lin C., Yang J., Liu P., Zhang J., Huang C, & Xia N. (2024). Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1. Nature Communications, 15, 9.

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LUAD and LUSC Tissue Microarray Analysis

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A LUAD tissue microarray (TMA, HLugA180Su06; Shanghai Outdo Biotech) and a LUSC tissue microarray (TMA, HLugS180Su01; Shanghai Outdo Biotech) were obtained from the National Engineering Center for Biochip in Shanghai. The TMA (HLugA180Su06) was constructed with 94 paired formalin-fixed, paraffin-embedded LUAD tissues and their corresponding adjacent normal tissues. The TMA (HLugS180Su01) was constructed with 90 paired formalin-fixed, paraffin-embedded LUSC tissues and their corresponding adjacent normal tissues. Patients were followed up for 8–10 years. Patients with diagnosed relapse as well as those who received preoperative radiation, chemotherapy or biotherapy were excluded. Demographic and clinical data were obtained from the patients’ medical records. Detailed clinicopathological information was listed in Supporting Information Tables S1 and S2.

Su T., Huang S., Zhang Y., Guo Y., Zhang S., Guan J., Meng M., Liu L., Wang C., Yu D., Kwan H.Y., Huang Z., Huang Q., Lai-Han Leung E., Hu M., Wang Y., Liu Z, & Lu L. (2021). miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis. Acta Pharmaceutica Sinica. B, 12(2), 821-837.

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IHC Evaluation of Rab27A in NSCLC

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Immunohistochemical (IHC) assays were performed as described previously^{39 (link)}. Tissue microarrays of 180 NSCLC tissues and matched adjacent normal tissues (90 pairs of adenocarcinomas: HLugA180Su02; 90 pairs of squamous cell carcinoma: HLugS180Su01; Outdo Biotech, Shanghai, China) were used to evaluate Rab27A protein expression. Tissue microarrays (ZL-LugA961) were obtained from Zhuolibiotech (Shanghai, China) to detect Rab27A and HSPA5 protein levels.

Zeng Y., Zhao J., Wu Z., Huang Y., Wang A., Zhu J., Xu M., Zhang W., Zhang X., Li J., Huang J.A, & Liu Z. (2024). Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis. NPJ Precision Oncology, 8, 74.

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