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Cobas 6000 c501 clinical chemistry analyzer

Manufactured by Roche

The Cobas® 6000 C501 is a clinical chemistry analyzer manufactured by Roche. It is designed to perform a variety of biochemical tests and assays on patient samples, providing healthcare professionals with analytical data to aid in diagnosis and treatment.

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2 protocols using cobas 6000 c501 clinical chemistry analyzer

1

Porcine Hematology and Blood Chemistry Analysis

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Following collection, blood samples were stored at 4°C before being delivered to the University of California, Davis, Veterinary Teaching Hospital (VMTH) Clinical Laboratory. Samples were analyzed within 4 h of collection. Hematological parameters were analyzed using an ADVIA® 120 Hematology System (Siemens Healthcare Diagnostics Inc., Tarrytown, NY) with a species-specific setting for pigs in the MultiSpecies System Software (Siemens Medical Solutions Diagnostics Inc., Tarrytown, NY, USA). The within-laboratory imprecision for the automated differentials (coefficient of variation, CV) for each variable, as determined by the VMTH Hematology Laboratory, is as follows: RBC 1.0%, HGB 0.8%, MCV 0.4%, RDW 0.6%, WBC 2.7%, and absolute counts for neutrophils 1.6%, lymphocytes 2.9%, monocytes 6.9%, eosinophils 8.8%, basophils 20%, and platelets 2.7%.
Blood chemistry analysis was performed using a Cobas® 6000 C501 Clinical Chemistry Analyzer (Roche Diagnostics, Indianapolis, IN) (Table 1). The CVs for each variable, as determined by the VMTH Clinical Chemistry Laboratory, are as follows: sodium 0.4%, potassium 0.0%, chloride 0.5%, bicarbonate 2.5%, phosphorus 1.3%, calcium 1.1%, BUN 0.7%, creatinine 1.8%, glucose 1.2%, total protein 0.9%, albumin 1.7%, AST 0.8%, creatine kinase 0.8%, alkaline phosphatase 0.5%, GGT 1.0%, total bilirubin 1.7% and SDH-37 2.2%.
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2

Hematologic and Biochemical Evaluation of Dietary Intervention and ETEC Exposure

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Whole blood and serum samples were collected from the superior vena cava on day 0 ('baseline'), day 21 after 3 weeks of standard or restricted diet ('3 weeks'), day 36 after 5 weeks of standard or restricted diet (with and without milk supplementation) ('5 weeks'), day 38 approximately 32 h after the first ETEC dose (Mid-ETEC) and day 39 (Post-ETEC) using heparin and additive-free collection tubes. Complete blood counts (CBC) and serum chemistry panels were analysed by the UC Davis Veterinary Medicine Teaching Hospital Clinical Diagnostic Laboratory using the ADVIA 120 hematology system (Siemens Healthcare Diagnostics Inc.) and Cobas 6000 C501 Clinical Chemistry Analyzer (Roche Diagnostics), respectively. A total of thirteen CBC and nineteen blood chemistry parameters were analysed.
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