Mmtv neu fvb n tg mmtvneu 202mul j

Manufactured by Jackson ImmunoResearch

MMTV-Neu (FVB/N-Tg(MMTVneu)202Mul/J) is a transgenic mouse model that expresses the Neu (HER2) oncogene under the control of the mouse mammary tumor virus (MMTV) promoter. This model is used for studying the development and progression of breast cancer.

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Bat gal b6 cg tg bat lacz 3picc j, by Jackson ImmunoResearch (2 mentions) Fvb n tg mmtv pyvt 634mul j, by Jackson ImmunoResearch (1 mentions) Mmtv pymt, by Jackson ImmunoResearch (1 mentions)

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FVB/N (31 citations) FVB/N-Tg(MMTVneu)202Mul/J (13 citations) MMTV-Neu (6 citations) MMTV-Neu-Tg (4 citations)

3 protocols using mmtv neu fvb n tg mmtvneu 202mul j

Transgenic Mouse Models for Breast Cancer

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MMTV-PyMT (FVB/N-Tg(MMTV-PyVT)634Mul/J, stock no. 002374) mice and MMTV-Neu (FVB/N-Tg(MMTVneu)202Mul/J, stock no. 002376) mice were obtained from the Jackson Laboratory. All animal experiments were performed under a protocol approved by the Animal Care and Use Committee of Hokkaido University (permission no. 14–0056). All mice were reared in self-ventilated cage, provided food and water ad libitum, and maintained with a 12:12-h light dark cycle. The health and behavior of the mice were monitored daily. All efforts were made to minimize suffering.

Otsuka Y., Oikawa T., Yoshino H., Hashimoto S., Handa H., Yamamoto H., Hashimoto A, & Sabe H. (2018). Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model. Cell Communication and Signaling : CCS, 16, 1.

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Genetically Engineered Mouse Models

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K-14 Cre (B6N.Cg-Tg(KRT14-cre)1Amc/J, stock no: 018964), MMTV-Neu (FVB/N-Tg(MMTVneu)202Mul/J, stock no: 002376), and BAT-Gal (B6.Cg-Tg(BAT-lacZ)3Picc/J, stock no. 005317) mice were purchased from Jackson Labs. All mice were bred and maintained in the University of Alabama at Birmingham (UAB) Animal Facility in accordance with the guidelines of the IACUC. In the article, use of ^−/− notation means that the animals are fl/fl, cre+and knockout confirmed.

Pruitt H.C., Metge B.J., Weeks S.E., Chen D., Wei S., Kesterson R.A., Shevde L.A, & Samant R.S. (2018). Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors. Oncogene, 37(12), 1610-1623.

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Transgenic Mouse Models for Cancer

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K14 Cre (B6N.Cg-Tg(KRT14-cre)1Amc/J, stock no: 018964), MMTV-Neu (FVB/N-Tg(MMTVneu)202Mul/J, stock no: 002376), and BAT-Gal (B6.Cg-Tg(BAT-lacZ)3Picc/J, stock no. 005317) mice were purchased from Jackson Labs. All mice were bred and maintained in the University of Alabama at Birmingham (UAB) Animal Facility in accordance with the guidelines of the IACUC. In the manuscript, use of −/− notation means that the animals are fl/fl, cre+ and knockout confirmed.

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