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230 protocols using spss statistics for mac

1

Nonparametric Analysis of Training Outcomes

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We summarized participant characteristics and outcomes using descriptive statistics. Non-parametric tests were used, since the variables were not normally distributed. We used median (interquartile range, IQR) for continuous variables and percentage for categorical variables. Changes before and after training were analyzed using Wilcoxon signed-rank test, Kruskal–Wallis, and McNemar test. We used SPSS Statistics for Mac (Version 27.0. Armonk, NY).
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2

Standardized Clinical Data Analysis

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Clinical data were collected prospectively and analyzed according to a standardized protocol as previously described (Plum et al. 2021 (link); Plum et al. 2020 (link); Plum et al. 2019 (link)). SPSS Statistics for Mac (Version 21, SPSS) was used for statistical analysis. Interdependence between stainings and clinical data were calculated using the Chi-squared and Fisher’s exact tests and displayed by cross-tables. Survival curves were plotted using the Kaplan–Meier method and analyzed using the log-rank test. All tests were two sided. P values < 0.05 were considered statistically significant.
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3

Survival Analysis of Clinical Data

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Clinical data were collected prospectively according to a standardized protocol. SPSS Statistics for Mac (Version 21, SPSS) was used for statistical analysis. Interdependence between stainings and clinical data was calculated using the chi-squared and Fisher's exact test, and displayed by cross-tables. Survival curves were plotted using the Kaplan-Meier method and analyzed using the log-rank test. Univariate and multivariate analyses were performed for prognostic factors of overall survival using the Cox regression model. All tests were two-sided and based on a significance level of P = .05.
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4

Tumor-Infiltrating T-Cell Analysis

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Clinical data were collected prospectively according to a standardized protocol. SPSS Statistics for Mac (Version 21, SPSS) was used for statistical analysis. Interdependence between stainings and clinical data was calculated using the chi-squared and Fisher’s exact tests, and displayed by cross-tables. Group differences were calculated by the t-test or ANOVA, respectively. Univariate cox-regression analysis was performed for determination of interdependence between survival time and number of T-cells in the tumor. Survival curves were plotted using the Kaplan–Meier method and analyzed using the log-rank test. All tests were two-sided. P values < 0.05 were considered statistically significant.
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5

Demographic Factors and Circle of Willis

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Statistical analysis was done using SPSS Statistics for Mac. The Chi-squared test was used to determine the impact of ethnicity, gender, and age on a complete CoW and its variant patterns. Data were demonstrated using tables, charts, and graphs.
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6

Biomarker-Based Survival Analysis

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Clinical data were collected prospectively according to a standardized protocol. SPSS Statistics for Mac (Version 21, SPSS) was used for statistical analysis. Interdependence between staining and clinical data was calculated using the chi-squared and Fisher’s exact tests, and displayed by cross-tables. Survival curves were plotted using the Kaplan-Meier method and analyzed using the log-rank test. Univariate and multivariate analyses were performed for prognostic factors of overall survival using the Cox regression model. All tests were two-sided. P values <0.05 were considered statistically significant.
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7

Anastomotic Leak Analysis in Esophagectomy

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For analysis of data, patients were divided into two groups based on CS (circular stapler) size (“small” = 25 mm circular stapler and “large” = 28 mm circular stapler). In addition, a subgroup analysis of patients who underwent a totally minimally invasive and a robotic esophagectomy was performed. Continuous variables are presented as means and range. Categorical data are presented as numbers and percentages. Student’s t-test (for continuous variables) and Fisher’s exact test (for nominal or categorical variables) were used for all bivariate analyses. Independent predictors of anastomotic leak were identified by a multivariate logistic regression analysis. All tests were two-sided, with statistical significance set at p ≤ 0.05. Data were analyzed by GraphPad Software (San Diego, CA, USA) and SPSS Statistics for Mac (version 21, SPSS).
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8

Comprehensive Tumor Heterogeneity Analysis

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Clinical data were collected prospectively according to a standardized protocol. For statistical analysis, SPSS Statistics for Mac (Version 21, SPSS) was used. Interdependence between staining and clinical data was calculated using the chi-squared and Fisher’s exact tests and displayed by cross-tables. Survival curves were plotted using the Kaplan-Meier method and analyzed using the log-rank test. The heatmap for visualization was generated via Microsoft Excel for Mac; it is considered to visualize the heterogeneity within the tumor and is not a heatmap as commonly used for gene signatures (e.g., next-generation-sequencing (NGS)). Univariate and multivariate analyses were performed for prognostic factors of overall survival, using the Cox regression model. All tests were two-sided; P values < 0.05 were considered statistically significant.
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9

Statistical Analysis of Stainings

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SPSS Statistics for Mac (Version 21, SPSS) was used for statistical analysis. Interdependence between stainings and clinical data were calculated using the chi-squared and Fisher’s exact tests, and displayed by cross-tables. Survival curves were plotted using the Kaplan–Meier method and analyzed using the log-rank test. All tests were two-sided. p values < 0.05 were considered statistically significant.
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10

Prognostic Factors of Overall Survival

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Clinical data were collected prospectively according to a standardised protocol. SPSS Statistics for Mac (Version 21, SPSS) was used for statistical analysis. Interdependence between staining and clinical data were calculated using the chi-squared and Fisher’s exact tests and displayed by cross-tables. Survival curves were plotted using the Kaplan–Meier method and analysed using the log-rank test. Univariate and multivariate analyses were performed for prognostic factors of overall survival using the Cox regression model. All tests were two-sided. p values < 0.05 were considered statistically significant.
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