Diethyl ether et2o

Manufactured by Thermo Fisher Scientific

Sourced in United States, United Kingdom

Diethyl ether (Et2O) is a highly volatile organic solvent commonly used in laboratory settings. It has a low boiling point and is widely employed as a solvent, extraction agent, and reagent in various chemical processes and analyses.

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Lab products found in correlation

Triisopropylsilane, by Oakwood Chemical (3 mentions) Septa capped vials, by Thermo Fisher Scientific (3 mentions) 2 methyltetrahydrofuran 2 methf, by Merck Group (3 mentions) Oxyma pure, by Merck Group (3 mentions) 4 dimethylaminopyridine dmap, by Thermo Fisher Scientific (3 mentions) Methyl tert butyl ether (mtbe), by Avantor (3 mentions) Dimethyl sulfide dms, by Thermo Fisher Scientific (3 mentions) Trityl oh chemmatrix, by Biotage (3 mentions) Acetonitrile, by Merck Group (3 mentions) Trifluoroacetic acid, by Merck Group (3 mentions) N n dimethylformamide (dmf), by Merck Group (3 mentions) 4 methylpiperidine 4 mepip, by Tokyo Chemical Industry (3 mentions) Ethanedithiol, by Merck Group (2 mentions) Diisopropylethylamine diea 1 bis dimethylamino methylene 1h 1 2 3 triazolo 4 5 b pyridinium 3 oxidhexafluorophosphate hatu diisopropylcarbodiimide, by Oakwood Chemical (2 mentions) 2 chlorotritylchloride polystyrene resin, by Bachem (2 mentions) Tentagel xv trityl chloride resin, by Rapp Polymere (2 mentions) Dimethyl acetylenedicarboxylate, by Merck Group (1 mentions) Potassium bromide, by Thermo Fisher Scientific (1 mentions) Methyl tert butyl ether (mtbe), by Thermo Fisher Scientific (1 mentions) Anhydrous dichloromethane dcm, by Merck Group (1 mentions)

Spelling variants of this product

Diethyl ether (196 citations) Diethyl ether (ether) (4 citations)

7 protocols using diethyl ether et2o

Synthesis of Organic Compounds Using Common Reagents

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Anhydrous dichloromethane (DCM) and tetrahydrofuran (THF) were purchased from Sigma Aldrich. Absolute ethanol was obtained from Decon Laboratories. Diethyl ether (Et₂O), methyl tert‐butyl ether (MTBE), and sodium azide were purchased from Fisher Scientific. Triethylamine (NEt₃) and methanesulfonyl chloride (MsCl) were obtained from Acros and distilled from CaH₂ and P₂O₅, respectively. Trifluoroacetic acid (TFA) was purchased from Oakwood Products. Pearlman's catalyst (Pd(OH)₂/C), 2,2,6,6‐tetramethylpiperidine‐1‐oxyl (TEMPO), phenylacetylene (PA), diphenylacetylene (DPA), dimethyl acetylenedicarboxylate (DMAD), and diethyl acetylenedicarboxylate (DEBD) were purchased from Sigma Aldrich and used as received. Potassium bromide and di‐tert‐butyl dicarbonate ((Boc)₂O) were purchased from Acros and used as received.

Edward Semple J., Sullivan B., Vojkovsky T, & Sill K.N. (2016). Synthesis and facile end‐group quantification of functionalized PEG azides. Journal of Polymer Science. Part A, Polymer Chemistry, 54(18), 2888-2895.

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Isoflavone and Metabolite Quantification

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Anhydrous sodium acetate, and diethyl ether (Et₂O) as well as HPLC or MS-grade acetonitrile, formic acid (≥98% purity), methanol, and water were purchased from Fisher Scientific (Fairlawn, NJ). Lyophilized glucuronidase/sulfatase from Helix pomatia, dimethyl sulfoxide, and equol were obtained from Sigma-Aldrich (St. Louis, MO). Daidzein, genistein, glycitein, daidzin, genistin, glycitin, acetyl daidzin, malonyl genistin, acetyl genistin were from LC laboratories division (PKC Pharmaceuticals, Inc, Woburn, MA) and malonyl daidzin, and malonyl glycitin from Wako Chemicals USA, Inc (Richmond, VA). Isoflavone metabolites (dihydrodaidzein, dihydrogenistein, ODMA, and 6-OH-ODMA) were from Plantech (Reading, UK).

Ahn-Jarvis J.H., Clinton S.K., Grainger E.M., Riedl K.M., Schwartz S.J., Lee M.L., Cruz-Cano R., Young G.S., Lesinski G.B, & Vodovotz Y. (2015). Isoflavone pharmacokinetics and metabolism after consumption of a standardized soy and soy-almond bread in men with asymptomatic prostate cancer. Cancer prevention research (Philadelphia, Pa.), 8(11), 1045-1054.

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Peptide Synthesis Using Fmoc Chemistry

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All solvents and reagents used were purchased from commercial sources and used without further purification. Fmoc-Ala-OH, Fmoc-Pro-OH, Fmoc-Trp (Boc)-OH, Fmoc-His (Trt)-OH, Fmoc-Leu- OH, Fmoc-Ser(tBu)-OH, Fmoc-Gln (Trt)-OH, Fmoc-Tyr (tbu)-OH, Fmoc-Arg (Pbf)-OH, Fmoc- Thr (tBu)-OH and Oxyma-Pure were ordered from Novabiochem (Millipore Sigma Corporation2,2,2-Trifluoroethanol (TFE), Dichloromethane (DCM), Dimethylformamide (DMF), Acetonitrile and Diethyl Ether (Et2O) were ordered from Fisher Scientific (Hampton, NH, United States). Trifluoroacetic acid (TFA), Diisopropylethylamine (DIPEA) and Piperidine were ordered from Chem-Impex International (Wood Dale, IL, United States). Amiodarone HCL, 3-(Tritylthio) propionic acid, Ethanedithiol (EDT), Triisopropylsilane (TIPS), 3-chloropropanethiol, 1,2,2,6,6- PentamethylPiperidine and Sodium Iodide were ordered from Sigma-Aldrich (St. Louis, MO, United States). 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate (TBTU) and 1- Hydroxybenzotriazole hydrate (HOBt) were ordered from P3 Biosystems (Louisville, KY, United States)., St. Louis, MO). Rink amide MBHA resin was ordered from vivitide, LLC (Garder, MA, United States).

Yurko R., Islam K., Weber B., Salama G, & Zahid M. (2023). Conjugation of amiodarone to a novel cardiomyocyte cell penetrating peptide for potential targeted delivery to the heart. Frontiers in Chemistry, 11, 1220573.

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Peptide Synthesis Reagents and Supplies

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N,N‐dimethylformamide (DMF), dichloromethane (DCM), acetonitrile (ACN), Oxyma Pure, ethanedithiol (EDT), 2‐methyltetrahydrofuran (2‐MeTHF), and trifluoroacetic acid (TFA) were purchased from Sigma‐Aldrich. Diisopropylethylamine (DIEA), 1‐[bis(dimethylamino)methylene]‐1H‐1,2,3‐triazolo[4,5‐b]pyridinium‐3‐oxidhexafluorophosphate (HATU), diisopropylcarbodiimide (DIC), Fmoc‐NHNH₂, and triisopropylsilane (TIS) were purchased from Oakwood Chemical. 2′‐Chlorotritylchloride polystyrene resin (200–400 mesh) and all standard Fmoc‐protected amino acids were purchased from Bachem Americas. 4‐Methylpiperidine (4‐MePip) was purchased from TCI America. Dimethyl sulfide (DMS) and 4‐dimethylaminopyridine (DMAP) were purchased from AlfaAesar. TentaGel® XV trityl chloride resin (XV18130.031) was purchased from Rapp Polymere. Trityl‐OH ChemMatrix® (7–600‐1310) was purchased from Biotage. Diethyl ether (Et₂O) and septa capped vials for storage under inert gas were purchased from Fisher Scientific. Methyl tert‐butyl ether (MTBE) was purchased from VWR.

Bird M.J, & Dawson P.E. (2022). A shelf stable Fmoc hydrazine resin for the synthesis of peptide hydrazides. Peptide Science (Hoboken, N.j.), 114(5), e24268.

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Synthesis of peptide compounds

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N,N-Dimethylformamide (DMF), dichloromethane (DCM), acetonitrile (ACN), Oxyma Pure, ethanedithiol (EDT), 2-methyltetrahydrofuran (2-MeTHF), and trifluoroacetic acid (TFA) were purchased from Sigma-Aldrich. Diisopropylethylamine (DIEA), 1-[bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium-3-oxidhexafluorophosphate (HATU), diisopropylcarbodiimide (DIC), Fmoc-NHNH₂, and triisopropylsilane (TIS) were purchased from Oakwood Chemical. 2’-Chlorotritylchloride polystyrene resin (200–400 mesh) and all standard Fmoc-protected amino acids were purchased from Bachem Americas. 4-Methylpiperidine (4-MePip) was purchased from TCI America. Dimethyl sulfide (DMS) and 4-dimethylaminopyridine (DMAP) were purchased from AlfaAesar. TentaGel® XV trityl chloride resin (XV18130.031) was purchased from Rapp Polymere. Trityl-OH ChemMatrix® (7–600-1310) was purchased from Biotage. Diethyl ether (Et₂O) and septa capped vials for storage under inert gas were purchased from Fisher Scientific. Methyl tert-butyl ether (MTBE) was purchased from VWR.

Bird M.J, & Dawson P.E. (2022). A shelf stable Fmoc hydrazine resin for the synthesis of peptide hydrazides. Peptide Science (Hoboken, N.j.), 114(5), e24268.

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Synthesis and Characterization of PLGA Scaffolds

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PLGA (Mw 180 kDa, (H-PLGA)), PLGA (Mw 75 kDa, (L-PLGA)), hydroxyethyl methacrylate (HEMA), inhibitor-remover (Al2O3) glycolide, and anhydrous toluene (PhCH3) were purchased from Sigma Aldrich (Dorset, UK). DL-Lactide, and tin octanoate (SnOct2) were purchased from Alfa Aesar (Lancashire, UK). Phosphate-buffered saline (PBS) was purchased from (Lonza, Slough, UK). Tetrahydrofuran (THF), and diethyl ether (Et2O) were purchased from Fisher (Loughborough, UK). Lactide and glycolide were recrystallized from ethyl acetate (EtOAc) prior to use. HEMA was passed through an inhibitor removal column immediately before use. Unless otherwise stated all other chemicals were used as received.

Upson S.J., Partridge S.W., Tcacencu I., Fulton D.A., Corbett I., German M.J, & Dalgarno K.W. (2016). Development of a methacrylate-terminated PLGA copolymer for potential use in craniomaxillofacial fracture plates. Materials science & engineering. C, Materials for biological applications, 69.

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Solid-Phase Peptide Synthesis Reagents

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N,N-Dimethylformamide (DMF), dichloromethane (DCM), acetonitrile (ACN), Oxyma Pure, ethanedithiol (EDT), 2methyltetrahydrofuran (2-MeTHF), and trifluoroacetic acid (TFA) were purchased from Sigma-Aldrich. Diisopropylethylamine (DIEA), 1-[bis(dimethylamino)methylene]-1H-1,2,3triazolo [4,5-b]pyridinium-3oxidhexafluorophosphate (HATU), diisopropylcarbodiimide (DIC), Fmoc-NHNH2, and triisopropylsilane (TIS) were purchased from Oakwood Chemical. 2'-Chlorotritylchloride polystyrene resin (200-400 mesh) and all standard Fmoc-protected amino acids were purchased from Bachem Americas. 4-Methylpiperidine (4-MePip) was purchased from TCI America. Dimethyl sulfide (DMS) and 4dimethylaminopyridine (DMAP) were purchased from AlfaAesar. TentaGel® XV trityl chloride resin (XV18130.031) was purchased from Rapp Polymere. Trityl-OH ChemMatrix® (7-600-1310) was purchased from Biotage. Diethyl ether (Et2O) and septa capped vials for storage under inert gas were purchased from Fisher Scientific. Methyl tert-butyl ether (MTBE) was purchased from VWR.

Bird M., & Dawson P.E. (2022). A Shelf Stable Fmoc Hydrazine Resin for the Synthesis of Peptide Hydrazides.

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