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Bromuconazole

Manufactured by Merck Group
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Bromuconazole is a fungicide used in laboratory settings. It is a triazole compound that inhibits ergosterol biosynthesis, a critical component of fungal cell membranes. Bromuconazole is used to study the effects of fungal inhibition in controlled experiments.

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Lab products found in correlation

Difenoconazole, by Merck Group (3 mentions) Tebuconazole, by Merck Group (2 mentions) Penconazole, by Merck Group (2 mentions) Metconazole, by Merck Group (2 mentions) Imazalil, by Merck Group (2 mentions) Epoxiconazole, by Merck Group (2 mentions) Isavuconazole, by Merck Group (1 mentions) Posaconazole, by Merck Group (1 mentions) Itraconazole, by Merck Group (1 mentions) Prothioconazole, by Merck Group (1 mentions) Fluconazole, by Merck Group (1 mentions) Voriconazole, by Merck Group (1 mentions) Prochloraz, by Merck Group (1 mentions) Pyraclostrobin, by Merck Group (1 mentions) Azoxystrobin, by Merck Group (1 mentions) Hexaconazole, by Merck Group (1 mentions) Ammonium persulphate, by Merck Group (1 mentions) Triticonazole, by Merck Group (1 mentions) Diniconazole, by Merck Group (1 mentions) Fenbuconazole, by Merck Group (1 mentions)

4 protocols using bromuconazole

1

Triazole Antifungal Powders: Characterization

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Triazole antifungal powders, difenoconazole (DFZ), epoxyconazole (EPZ), penconazole (PNZ), tebuconazole (TBZ), metconazole (MTZ), bromuconazole (BMZ), prothioconazole (PTZ), fluconazole (FCZ), voriconazole (VOR), itraconazole (ITR), posaconazole (POZ) and isavuconazole (ISZ) were obtained from Sigma Aldrich, France.
Drakulovski P., Krasteva D., Bellet V., Randazzo S., Roger F., Pottier C, & Bertout S. (2023). Exposure of Cryptococcus neoformans to Seven Commonly Used Agricultural Azole Fungicides Induces Resistance to Fluconazole as Well as Cross-Resistance to Voriconazole, Posaconazole, Itraconazole and Isavuconazole. Pathogens, 12(5), 662.
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2

Antifungal Susceptibility Testing of DMIs

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AFST with 14-α demethylation inhibiting fungicides (DMIs) was performed following the EUCAST methodology as described before. Environmental DMIs tested for microdilution assay were two imidazole drugs, imazalil and prochloraz; and five triazole drugs, tebuconazole, epoxiconazole, difenoconazole, bromuconazole and metconazole, all of them purchased at Sigma-Aldrich Química, Madrid, Spain. The final concentrations of each azole drug tested ranged from 0.06 to 32 mg/L. MICs were visually read as described before. Clinical breakpoints for DMIs have not been standardized yet so wild-type strain MICs were considered as susceptible.
Gonzalez-Jimenez I., Lucio J., Amich J., Cuesta I., Sanchez Arroyo R., Alcazar-Fuoli L, & Mellado E. (2020). A Cyp51B Mutation Contributes to Azole Resistance in Aspergillus fumigatus. Journal of Fungi, 6(4), 315.
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3

Nano-Cs-NAT Synthesis and Analysis

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The reagents required for Nano-Cs-NAT synthesis: medium molecular weight chitosan, N-isopropylacrylamide, acrylic acid, triethylene glycol dimethacrylate, and ammonium persulphate, were all supplied by Sigma-Aldrich (Steinheim, Germany), as well as the analytical standards of penconazole, imazalil, hexaconazole, usilazole, triticonazole, diniconazole, epoxiconazole, fenbuconazole, bromuconazole, pyraclostrobin, azoxystrobin and difenoconazole. LC-MS grade acetonitrile, methanol and water were purchased by Merck (Darmstadt, Germany). Acetic acid was acquired from Fisher Scientic (Waltham, MA, USA). Working solutions were daily prepared from methanol stock solutions conserved at -20 °C.
Martello L., Rapti A., Bikiaris D.N, & Lambropoulou D.A. (2024). Synthesis and evaluation of a chitosan nanomaterial as efficient sorbent for determination of fungicide residues in waters and wine by liquid chromatography high resolution mass spectrometry. Analytical methods : advancing methods and applications, 16(6).
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4

Bromuconazole and Fluorescent Assays

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Bromuconazole (1-[[4-bromo-2-(2,4-dichlorophenyl) tetrahydro-2-furanyl] methyl]-1H-1,2,4-triazole); 2,4-Dinitro-phenylhydrazine (2,4-DNPH); 2,7-Dichloro uoresce diacetate (DCFH-DA); Low melting point agarose (LMA) and normal melting point agarose (NMA) were purchased from Sigma (Steinheim, Germany).
Rjiba K., Hamdi H., M’nassri A., Guedri Y., Mokni M., & Abid S. (2021). Bromuconazole caused genotoxicity, hepatic and renal failure via oxidative stress process in Wistar rats.
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