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Human genome 1.0 st array

Manufactured by Agilent Technologies

The Human Genome 1.0 ST Array is a microarray-based platform designed for whole-genome gene expression analysis. The array provides comprehensive coverage of the human transcriptome, enabling researchers to study gene expression patterns across the entire genome. The core function of this product is to facilitate large-scale, high-throughput gene expression profiling studies.

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2 protocols using human genome 1.0 st array

1

Transcriptomic Analysis of Crohn's Disease

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GEO (http://www.ncbi.nlm.nih.gov/geo) (Edgar et al., 2002 (link)) is a public functional genomics data repository of high throughput gene expression data, chips and microarrays. The GSE75214 (Vancamelbeke et al., 2017 (link)) and GSE102133 (Verstockt et al., 2019 (link)) datasets generated using the Affymetrix GPL6244 platform, (Affymetrix Human Genome 1.0 ST Array), and GSE179285 (Keir et al., 2021 (link)) generated on the GPL6480 platform (Agilent-014850 Whole Human Genome Microarray 4 × 44K G4112F) were downloaded from GEO. Annotated information from the platform was used to convert the probes to the corresponding gene symbols. The GSE179285 dataset contained 47 CD intestinal mucosa tissue samples and 31 controls; the GSE75214 dataset contained 59 CD samples and 22 healthy controls; and the GSE102133 dataset contained 65 intestinal mucosal biopsies from CD patients and 12 intestinal mucosal tissues from controls.
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2

Transcriptional Profiles of Ulcerative Colitis

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GEO (http://www.ncbi.nlm.nih.gov/geo) (Edgar et al., 2002 (link)) is a public functional genomics data repository of high throughput gene expression data, chips and microarrays. The GSE75214 (Vancamelbeke et al., 2017 (link)) and GSE48958 (Van der Goten et al., 2014 (link)) datasets generated using the Affymetrix GPL6244 platform (Affymetrix Human Genome 1.0 ST Array), and GSE179285 (Keir et al., 2021 (link)) generated on the GPL6480 platform (Agilent-014850 Whole Human Genome Microarray 4 × 44K G4112F) were downloaded from GEO. Annotated information from the platform was used to convert the probes to the corresponding gene symbols. The GSE179285 dataset contained 23 UC inflamed colonic mucosa tissue samples and 23 control samples; the GSE75214 dataset contained 74 biopsies from inflamed colonic mucosa of active UC patients and 11 healthy control samples; and the GSE48958 dataset contained 7 colonic mucosal biopsies from UC patients with active disease and 8 colonic mucosal biopsies from controls.
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