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Ge signa scanner

Manufactured by GE Healthcare
Sourced in United States

The GE Signa scanner is a magnetic resonance imaging (MRI) system designed for diagnostic imaging in healthcare settings. It uses a strong magnetic field and radio waves to generate detailed images of the body's internal structures. The Signa scanner's core function is to capture high-quality images that enable healthcare professionals to diagnose and monitor medical conditions.

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37 protocols using ge signa scanner

1

Neuroanatomical MRI Acquisition Protocol

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Neuroanatomical MRI was acquired on 370 participants on a 1.5-T GE Signa scanner (Milwaukee, WI) at both baseline and follow up. Sixty-eight participants had aMRI acquired on a 3-T GE Signa scanner (Milwaukee, WI) at both time points. Twenty children were scanned on a 1.5-T scanner at baseline and a 3-T scanner at follow-up. Imaging parameters are given as supplemental information.
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2

High-Resolution Structural and Functional MRI Acquisition

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Scanning was done using a 3.0 T Signa GE scanner with an 8‐channel phased‐array head coil. For each subject, a high‐resolution structural image was acquired through a three‐dimensional MRI sequence with a voxel size of 1 mm × 1 mm × 1 mm, using an axial fast spoiled gradient recalled sequence with the following parameters: repetition time = 1900 ms, echo time = 2.6 ms, data matrix = 256 × 256, and field of view (FOV) = 256 × 256 mm.
The functional datasets were acquired using a T2*‐weighted echo‐planar imaging sequence. The parameters were as follows: repetition time = 2000 ms, echo time = 30 ms, data matrix = 64 × 64, voxel size = 3.75 mm × 3.75 mm × 4 mm, FOV = 240 mm × 240 mm, flip angle = 90°, and slices = 35 with no gap.
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3

Resting-State fMRI Acquisition Protocol

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MR imaging was performed using a whole-body 3T Signa GE scanner (GE, Waukesha, Wis.) with a standard transmit-receive head coil. Whole-brain sagittal R-fcMRI data sets were obtained in eight minutes with a single-shot gradient echo-echo planar imaging pulse sequence. Participants were instructed to close their eyes and relax, and no specific cognitive tasks were performed. The R-fcMRI imaging parameters were: TE = 25 ms, TR = 2000 ms, flip angle of 90°, number of slices = 36, slice thickness = 4 mm, matrix size = 64 × 64, and field of view = 240 × 240 mm. High-resolution 3D spoiled gradient-recalled echo (SPGR) axial images were acquired for anatomical reference. The parameters were: TE/TR/TI of 4/10/450 ms, flip angle of 12°, number of slices = 144, slice thickness = 1 mm, matrix size = 256 ×192 and FOV = 240 × 240 mm.
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4

Neuroanatomical Markers in Psychotic Disorders

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3D GRASS T1-MPRAGE scans were obtained using a 1.5-T Signa GE Scanner and scan parameters can be found in our previous study (Keshavan, Sanders, et al., 2003 (link)). Automated brain segmentation was performed using FreeSurfer 6.0 and we used the Brodmann area maps to parcellate the V1, V2, and V5/MT regions using a semi-automated process (Fischl et al., 2008 (link)) as previously described by our group (Lizano, Lutz, et al., 2019 (link)). The Brodmann area atlas was visually inspected for proper segmentation (quality control), audited by the author (IA) and rated between 0 (low quality), 1, and 2 (high quality). Participants with low quality MRI scans (n=6) were excluded. Area and volume values were summed, while thickness measures were averaged for the left and right hemisphere.
The final sample included 102 participants, HC n=44, FEP-SZ n=36 (schizophrenia n=9, schizophreniform n=1, schizoaffective disorder n=5, and residual/unspecified SZ diagnosis n=21) and FEP-NSZ n= 22 (bipolar disorder n=2, major depressive disorder n=9, brief reactive psychosis n=10, and delusions disorder n=1).
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5

Resting-state fMRI Acquisition Protocol

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Imaging was performed using a whole-body 3T Signa GE scanner with a standard quadrature transmit receive head coil. During the resting-state acquisitions, no specific cognitive tasks were performed, and the study participants were instructed to close their eyes and relax inside the scanner. High-resolution SPGR 3D axial images were acquired for anatomical reference. The number of slices is 144, slice thickness is 1 mm, matrix size is 256 × 192. The sagittal rsfMRI datasets of the whole brain were obtained in 10 minutes with a single-shot gradient echo-planar imaging (EPI) pulse sequence. The fMRI imaging parameters were: echo time (TE) of 25 ms, repetition time (TR) of 2 s, flip angle of 90°; 36 slices were obtained without gap; slice thickness was 4 mm with a matrix size of 64 × 64 and field of view of 24 × 24 cm.
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6

Dose Escalation Partial Breast Radiotherapy

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This study included 16 patients who enrolled on a preoperative, dose escalation, single‐fraction partial breast radiotherapy clinical protocol at Duke. Prior to CT scan, all patients had one titanium biopsy marker implanted to identify the tumor. Patients underwent CT (GE LightSpeed RT; GE Medical System, Milwakee, WI) scanning with 2.5 mm slice thickness in the prone position on a CDR prone breast board (CDR Systems Inc, Calgary, AB, Canada), which was placed on top of the CT table and treatment couch. The head was turned to the ipsilateral side and both arms were raised up to hold the handles above the head. The ipsilateral breast (ILB) was allowed to fall naturally through the opening of the prone breast board while the contralateral breast(21) was pulled away with the support of the bridge plate on the board.(22) CT origin was marked on the patient's skin and the board. Patients also underwent MRI in the prone position (1.5 Tesla GE Signa scanner; GE Medical System) using the open breast array MRI coil (GE Medical System). T1 weighted and dynamic contrast‐enhanced MR images were acquired to delineate the tumor.
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7

Diffusion Weighted Imaging in Young Children

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MR scans were performed using a 3T GE-Signa scanner (GE Healthcare, Milwaukee, WI) equipped with an 8-channel head coil and ASSET. DWI was acquired with a multi-slice single shot diffusion weighted echo-planar-imaging (EPI) sequence at repetition time (TR) = 12,500 ms, echo time (TE) = 88.7 ms, field of view (FOV) = 240 mm, 128×128 acquisition matrix (nominal resolution = 1.89 mm), contiguous 3 mm thickness in order to cover entire axial slices of the whole brain using 55 isotropic gradient directions with b= 1000s/mm2, one b=0 acquisition, and number of excitations (NEX)=1 [5 (link)]. Approximate scanning time for the acquisition was 12 minutes using double refocusing pulse sequence to reduce eddy current artifacts. Only children with neurological condition younger than age 4 years (being scanned clinically) were sedated using pentobarbital (3 mg/kg) followed by fentanyl (1 mg/kg).
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8

Resting-state fMRI in Recurrent Depression

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At UM (n = 11 HC, n = 16 rMDD), scans were collected with a 3.0 T GE Signa scanner (USA) using T2*-weighted single shot reverse spiral sequence with the following parameters: 90 degree flip, field-of-view 20, matrix size = 64 × 64, slice thickness 4mm, 30 ms echo time, 29 slices. At UIC (n = 36 HC, n = 57 rMDD) scans were collected with a 3.0 T GE Discovery Scanner (USA) using parallel imaging with ASSET and T2* gradient-echo axial echo planar imaging (EPI) with the following parameters: 90 degree flip, field-of-view 22, matrix size = 64 × 64, slice thickness = 3 mm, 22.2 ms echo time, 44 slices. Both sites used a repetition time (TR) of 2000 ms, with 240 total TRs collected and interleaved slice acquisition. High-resolution anatomic T1 scans were obtained for spatial normalization at both sites. Motion was minimized with foam pads, by instructing participants to gaze on a visual tracking line (UIC only) and/or crosshair (UIC and UM) on the display, and by conveying the importance of holding still to participants.
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9

Diffusion-Weighted MRI Brain Imaging

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All participants underwent a 3T diffusion weighted MRI with eight channel head coil (GE-Signa scanner, GE Healthcare, Milwaukee, WI) at TR = 12,500ms, TE = 88.7ms, FOV = 24cm, 128×128 acquisition matrix (nominal resolution = 1.89mm), contiguous 3mm thickness in order to cover entire axial slices of whole brain using 55 isotropic gradient directions with b= 1000s/mm2, one b=0 acquisition, and number of excitations=1. The present study utilized the NIH TORTOISE DIFF_PREP software package to correct motion and eddy current distortion in the diffusion weighted MRI data (https://science.nichd.nih.gov/confluence/display/nihpd/TORTOISE).
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10

Comprehensive Brain Imaging with DTI

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MR scans were performed using a 3T GE-Signa scanner (GE Healthcare, Milwaukee, WI) equipped with an 8-channel head coil and ASSET. DTI was acquired with a multi-slice single shot diffusion weighted echo-planar-imaging (EPI) sequence at repetition time = 12,500 ms, echo time = 88.7 ms, field of view (FOV) = 240 mm, 128×128 acquisition matrix (nominal resolution = 1.89 mm), contiguous 3 mm thickness in order to cover entire axial slices of the whole brain using 55 isotropic gradient directions with b= 1000s/mm2, one b=0 acquisition, and number of excitations = 1. Children with neurological conditions being scanned clinically were sedated, if needed, using pentobarbital (3 mg/kg) followed by fentanyl (1μg/kg).
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