4 methylmorpholine nmm

Manufactured by Merck Group

4-methylmorpholine (NMM) is a colorless, volatile liquid organic compound. It is used as a solvent and a building block in organic synthesis.

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Lab products found in correlation

Fmoc protected amino acids, by AAPPTec (1 mentions) Acetic anhydride ac2o, by Thermo Fisher Scientific (1 mentions) Cell lysis buffer, by Thermo Fisher Scientific (1 mentions) Novex 4 20 tris glycine gel, by Thermo Fisher Scientific (1 mentions) Glyceraldehyde 3 phosphate dehydrogenase gapdh, by Santa Cruz Biotechnology (1 mentions) Phosphate buffer saline (pbs), by Merck Group (1 mentions) Sulfuric acid, by Merck Group (1 mentions)

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4-methylmorpholine (12 citations)

2 protocols using 4 methylmorpholine nmm

Optimizing Peptide Synthesis and Cell Culture Techniques

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Fmoc-protected amino acids were purchased from AAPPTEC (Louisville, KY) and EMD Biosciences (San Diego, CA). Resins were obtained from Chem-Implex (Wood Dale, IL), N-methyl-2-pyrrolidinone (NMP) from Advanced ChemTech (Louisville, KY), and 4-methylmorpholine (NMM) from Sigma-Aldrich (St. Louis, MO); all were used without further purification. Acetic anhydride (Ac₂O) was purchased from Fisher Scientific (Pittsburgh, PA). All the cancer cell lines and media were obtained from American Type Culture Collection (ATCC, Manassas, VA). PathHunter assay kit was from DiscoverX technologies (Fremont, CA). For Western blot experiment, Novex^® 4–20% tris-glycine gels and cell lysis buffer were ordered from Life Technologies (Grand Island, NY) and antibodies from Abcam, Inc. (Cambridge, MA). The antibodies for the housekeeping protein glyceraldehyde 3-phosphate dehydrogenase (GAPDH) were purchased from Santa Cruz Biotechnology, Inc. (Dallas, TX).

Kanthala S., Gauthier T, & Satyanarayanajois S. (2014). Structure-activity Relationships of Peptidomimetics that Inhibit PPI of HER2-HER3. Biopolymers, 101(6), 693-702.

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Synthesis of Hyaluronic Acid Conjugates

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Sodium salt Hyaluronate (HA) isolated from Streptococcus equi with average Mw 1.2 MDa was purchased from Caldic (Origgio, Varese, Italy). Ornithine methyl ester (H-Orn-OMe^. 2HCl) was purchased from Bachem. 4-methylmorpholine (NMM), NaCl, 0.025 M sodium tetraborate, sulfuric acid, and acetonitrile were purchased from Sigma–Aldrich. 2-chloro-dimethoxy-1,3,5-triazine (CDMT) purchased from TCI. The phosphate buffer saline (PBS) was purchased from Sigma–Aldrich (Sigma-Aldrich SRL, Milano, Italy).

Sciabica S., Tafuro G., Semenzato A., Traini D., Silva D.M., Reis L.G., Canilli L., Terno M., Durini E., Vertuani S., Baldisserotto A, & Manfredini S. (2021). Design, Synthesis, Characterization, and In Vitro Evaluation of a New Cross-Linked Hyaluronic Acid for Pharmaceutical and Cosmetic Applications. Pharmaceutics, 13(10), 1672.

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