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Sald 2100

Manufactured by Shimadzu
Sourced in Japan

The SALD-2100 is a laser diffraction particle size analyzer manufactured by Shimadzu. It is designed to measure the particle size distribution of various materials, including powders, suspensions, and emulsions. The instrument uses the principle of laser diffraction to determine the particle size, providing accurate and reliable results across a wide range of particle sizes.

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4 protocols using sald 2100

1

Melt-Kneaded Spherical Resin Powder Production

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Example 12

Materials were melt-kneaded in each composition ratio shown in Table 9 using a biaxial extruder to produce pellets. The cylinder temperature of the biaxial extruder was 270° C. to 300° C. The obtained pellets and polyethylene oxide were melt-mixed at 280° C. to 300° C. and the resultant mixture was immersed in water to dissolve polyethylene oxide in water, thus obtaining spherical resin powder. The average particle diameter of the spherical resin powder was measured with a laser diffraction particle size distribution measurement device (SALD-2100 manufactured by Shimadzu Corporation). The average particle diameters of Example 12, Comparative Example 9, and Comparative Example 10 were 70 μm, 50 μm, and 50 μm, respectively.

TABLE 9
Comp.Comp.
Ex. 12Ex. 9Ex. 10
Inorganicpotassium% by mass20
fiberstitanate
ThermoplasticPPS resin% by mass8010050
resin
Otherglass beads% by mass50
additives

<Production of Three-Dimensional Shaped Object Based on Powder Bed Fusion Process

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2

Grain Size and BET Surface Area of Sulfide Samples

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The grain size and Brunauer–Emmett–Teller (BET) surface area (ABET) of the ground sulfide samples were measured using a laser diffraction particle size analyzer (SALD-2100, Shimadzu, Co., Kyoto, Japan) and a high-precision gas/vapor adsorption measurement instrument (BELSORP-max, MicrotracBEL Corp., Osaka, Japan), respectively, at the National Institute for Materials Science (NIMS; Tsukuba, Japan). The mode values of the grain sizes for samples CKL-1, CKL-2, CKL-3, and CKL-4 were 21, 17, 14, and 14 µm, respectively, while the respective surface areas were 0.45, 0.41, 1.0, and 0.71 m2 g−1 (Table 1).
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3

Crosslinked Recombinant Collagen Peptide Composites

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An aqueous solution of recombinant human collagen peptide (7.5%, cellnest TM , FUJIFILM Wako Pure Chemical Corp., Osaka, Japan) was freeze-dried and pulverized into approximately 1-mm granules by a granulator (Quadro Comil U5, Quadro Engineering Corp., Waterloo, Canada). Subsequently, thermal crosslinking at 142°C for 5 h was carried out using a vacuum drying oven (DP-43, Yamato Scientific Co., Ltd., Tokyo, Japan) to obtain RCP. The size of RCP was measured as mass-median-diameter (D50) using a static image analysis system (Morphologi G3, Malvern Panalytical Ltd., Malvern, UK). β-TCP (β-TCP-100 milled product, Taihei Chemical Industrial Co., Ltd., Osaka, Japan) was pulverized into submicron size by the Nanovater (NVL-AS200-D10, Yoshida Kikai Co., Ltd., Nagoya, Japan) and dispersed into water. The particle size of β-TCP was measured as D50 using a particle size distribution measuring apparatus (SALD-2100, Shimadzu Corp., Kyoto, Japan). Subsequently, 500 μL of β-TCP dispersion (concentrations: 0, 0.01, 0.1, and 1 wt%) were added into 100 mg freeze-dried RCP to swell (Fig. 1A).
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4

Blending and Characterization of Pharmaceutical Powders

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Microcrystalline cellulose (PH-101, Asahi Kasei Corp., Japan), milled lactose monohydrate (Pharmatose Ⓡ 80M, DFE Pharma, Germany), lactose hydrate prepared by fluidized bed granulation (Dilactose Ⓡ S, FREUND Corp., Japan), and magnesium stearate (Parteck LUB MST, Merck KGaA, Germany) were used in this study. The medium diameters were measured using a laser diffraction particle analyzer (SALD 2100, Shimadzu Corp.) and true densities of the powder materials were obtained by the literature (Table 1). [31] [32] [33] [34] [35] Four types of sample powders were used in this study: milled lactose hydrate (Lac), microcrystalline cellulose (MCC), a mixed powder of Lac and MCC with 95 wt% of Lac (Lac/MCC), and lactose hydrate prepared by fluidized bed granulation (DiLac).
Lac was the non-modified lactose monohydrate with a relatively large particle size. DiLac was the lactose granule for direct compression. Magnesium stearate (0.5 wt%) was used as a lubricant.
Powder samples were manually blended in a polyethylene bag for 5 min.
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