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Navious ex

Manufactured by Beckman Coulter
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The Navious EX is a laboratory instrument designed for automated sample preparation and analysis. It is capable of performing various tasks such as liquid handling, sample dilution, and mixed-mode chromatography. The Navious EX is a versatile tool that can be used in a wide range of applications, including pharmaceutical research, environmental testing, and clinical diagnostics.

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Lab products found in correlation

Sars cov 2 s1 mixed peptide pools, by Mabtech (1 mentions)

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Navious

2 protocols using navious ex

1

Lymphocyte Profile Determination

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Absolute numbers of lymphocytes, CD3, CD4, and CD8 T-cells, B-cells and NK-cells were routinely determined in fresh blood samples collected at T1, with a Navious EX flow cytometer (Beckman-Coulter, Brea, California), by standard procedures at the Immunology Service of our hospital.
Pozo-Balado M.D., Bulnes-Ramos Á., Olivas-Martínez I., Garrido-Rodríguez V., Lozano C., Álvarez-Ríos A.I., Sánchez-Sánchez B., Sánchez-Bejarano E., Maldonado-Calzado I., Martín-Lara J.M., Santamaría J.A., Bernal R., González-Escribano M.F., Leal M, & Pacheco Y.M. (2023). Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing home. Immunity & Ageing : I & A, 20, 9.
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2

Functional T-Cell Response to SARS-CoV-2

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The splenocytes harvested from immunized mice were grinded into a single cell suspension. The suspended cells were seeded on 96-well U-bottom plates at density of 2 × 106 cells/well and stimulated with SARS-CoV-2 S1 mixed peptide pools (2 μg/mL, Mabtech) for 18–20 hours. The resulting cells were harvested for surface and intracellular markers staining. Cells were first incubated with anti-CD4 and anti-CD8 antibodies for surface staining followed by intracellular staining with anti-IFN-γ, anti-IL-4, and anti-Granzyme B antibodies (Biolegend). All flow cytometry data was acquired by Navious EX flow cytometer (Beckman Coulter) and analyzed by Kaluza software.
Yang M.C., Wang C.C., Tang W.C., Chen K.M., Chen C.Y., Lin H.H., Hsieh Y.C., Wang N.H., Kuo Y.C., Chu P.T., Tung H.Y., Wu Y.C., Sun J.L., Liu S.Y., Li W.F., Lee W.H., Lai J.S., Chang M, & Lai M.T. (2023). Immunogenicity of a spike protein subunit-based COVID-19 vaccine with broad protection against various SARS-CoV-2 variants in animal studies. PLOS ONE, 18(3), e0283473.
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