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Architect anti hbs assay

Manufactured by Abbott
Sourced in Japan

The Architect anti-HBs assay is a quantitative immunoassay used to detect and measure the presence of hepatitis B surface antibodies (anti-HBs) in human serum or plasma samples. The assay is designed to be used on the Architect i1000SR and i2000SR analyzers.

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2 protocols using architect anti hbs assay

1

Antibody Titers in Vaccinated HCWs

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Antibody titers were tested by Abbott Architect anti-HBs assay on the Architect i2000 system (Abbott, Chicago, IL). We also divided all vaccinated HCWs (n=166) into two groups on the basis of completion of their full schedule of vaccination. Group A: those who had completed vaccination more than 5 years ago, and Group B: those who had completed vaccination less than 5 years ago. Another comparison was done between the subjects who had received the booster vaccination less or more than 1 year ago.
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2

HBV Serology and DNA Quantification

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Serum titers of HBsAg and anti-HBs were measured by chemiluminescence immunoassays using the Architect HBsAg-QT assay and Architect anti-HBs assay (Abbott, Tokyo, Japan), and the lower-limits of detection were 0.05 IU mL−1 and 10 mIU mL−1, respectively. Anti-HBc was measured by chemiluminescence immunoassays using the Architect Anti-HBc assay (Abbott, Japan), with a cutoff value of 121 (link),22 (link). Serum HBV-DNA level was analyzed by TaqMan polymerase chain reaction (PCR) assay (Cobas AmpliPrep/Cobas TaqMan HBV test, v2.0), and the quantitative range was 1.3–8.3 log10 IU mL−1.
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