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L 741 626 1003

Manufactured by Bio-Techne

L-741,626 (1003) is a selective dopamine D1 receptor antagonist. It is a laboratory research tool used in the study of the dopamine D1 receptor and its signaling pathways.

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4 protocols using l 741 626 1003

1

Neurotransmitter Receptor Modulation Protocol

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L-DOPA (3788) and L-741,626 (1003) were from Tocris. Methylphenidate and desipramine were from Sigma. All other reagents were from either Sigma-Aldrich or Fisher Scientific and were of the highest possible grade.
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2

Neurotransmitter Receptor Assay Protocol

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L-DOPA (3788) and L-741,626 (1003) were from Tocris. Methylphenidate and desipramine were from Sigma. All other reagents were from either Sigma-Aldrich or Fisher Scientific and were of the highest possible grade.
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3

Dopamine Receptor Signaling in Autophagy

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Pramipexole dihydrochloride (4174), (-)-quinpirole hydrochloride (1061), L-741,626 (1003) and GR103,691 (1109) were purchased from Tocris Bioscience. Retinoic acid (R2625), TPA (P8139), dexpramipexole dihydrochloride (SML0392), EBSS, and all other reagents unless specified were purchased from Sigma-Aldrich. BAPTA-AM (B-1205) and Fura-2-AM (F1221) were from Invitrogen. Quin-2-AM (SC-215769) was from Santa Cruz Biotechnology. The primary antibodies for immunoblot analysis were listed as follows: LC3B (Abcam, ab62721), BECN1 (Santa Cruz Biotechnology, sc11427), SQSTM1 (Sigma, P0067), FOS (Abcam, ab7963), p-MTOR (S2448)/MTOR (Cell Signaling Technology [CST], 5536/2938), p-RPS6KB1 (T389)/RPS6KB1 (CST, 9208/2708), p-ULK1 (S757; CST, 6888), p-ULK1 (S555; Chemicon, 2449230), ULK1 (CST, 4773), PtdIns3K (CST, 4263s), DRD2 (Chemicon, AB1558O), DRD3 (Chemicon, AB1785P), p-CAMK4 (T196)/CAMK4 (Santa Cruz Biotechnology, sc-28443/sc-166156), p-CREB (S133)/CREB (CST, 9198S/9104S), p-MAPK8 (Thr183/Tyr185)/MAPK8 (CST, 4671/3708), p-JUN (S63)/JUN (Santa Cruz Biotechnology, sc822/sc1694), SNCA (CST, 2642), HTT (Chemicon, MAB2166), ACTB (Sigma, A3584), TUBB/β-tubulin (Sigma, T0198), and GAPDH (Beyotime, AG019).
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4

Neurotransmitter Receptor Assay Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
L-DOPA (3788) and L-741,626 (1003) were from Tocris. Methylphenidate and desipramine were from Sigma. All other reagents were from either Sigma-Aldrich or Fisher Scientific and were of the highest possible grade.
+ Open protocol
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