Balb c nude male mice

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BALB/c nude male mice are an immunodeficient mouse strain that lack functional T cells. They are commonly used in research as a model for studying the immune system and evaluating the efficacy of therapeutic interventions.

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2 protocols using balb c nude male mice

Nude Mouse Model for Preclinical Studies

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For in vivo studies, the BALB/c nude male mice (25–30 g; 6–8 weeks of age) were used and purchased from Envigo (Milan, Italy). Animals were placed in a controlled environment and were fed with a standard diet and water ad libitum under pathogen-free conditions with a 12 h light/12 h dark. Animal study was approved by the University of Messina (n◦ 368/2019-PR released on 14 May 2019) in accordance with Italian regulations on the use of animals (D.M.116192) and Council Regulation regulations (EEC) (O.J. of E.C. L 358/1 12/18/1986).

Basilotta R., Lanza M., Filippone A., Casili G., Mannino D., De Gaetano F., Chisari G., Colarossi L., Motta G., Campolo M., Cuzzocrea S., Paterniti I, & Esposito E. (2023). Therapeutic Potential of Dimethyl Fumarate in Counteract Oral Squamous Cell Carcinoma Progression by Modulating Apoptosis, Oxidative Stress and Epithelial–Mesenchymal Transition. International Journal of Molecular Sciences, 24(3), 2777.

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BALB/c Nude Mouse Model for Research

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BALB/c nude male mice (25–30 g; 6–8 weeks of age) were purchased from Envigo (Milan, Italy). Animals were placed in a controlled environment and were fed with a standard diet and water ad libitum under pathogen-free conditions with a 12 h light/12 h dark cycle. The animal study was approved by the University of Messina (n° 783/2021-PR) following Italian regulations on the use of animals (D.M.116192) and Directive legislation (EU) (2010/63/EU) amended by Regulation (EU) 2019/1010.

Filippone A., Casili G., Scuderi S.A., Mannino D., Lanza M., Campolo M., Paterniti I., Capra A.P., Colarossi C., Bonasera A., Lombardo S.P., Cuzzocrea S, & Esposito E. (2022). Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling. Cancers, 15(1), 217.

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