All individuals underwent a paired unenhanced chest CT and electrocardiography (ECG)-gated cardiac CT scans; details regarding the scan protocol and scan parameters have previously been described.11 (link),12 (link) In brief, an Aquilion One Vision Edition scanner (Toshiba Medical Systems, Otawara, Japan) was used for both image acquisitions with the following settings: 120 kVp (both CT modalities), automated exposure control (SD15 and SD55), and reconstruction with filtered back projection and a soft tissue kernel (1 mm slice thickness) for chest CT scans and 3 mm slice thickness and interval for ECG-gated cardiac CT scans. Both CT modalities were acquired in sequence during the same visit. The chest CT was acquired during a deep inspiratory breath-hold, whereas the cardiac CT was acquired during a normal inspiratory breath-hold (around 50% of maximum lung capacity). Chest CT was acquired using spiral image acquisition including the entire lungs, whereas cardiac CT was acquired using ECG-gated, single rotation with a Z-axis from 8 to 16 cm depending on heart length in the Z-axis.
Aquilion one vision edition scanner
Manufactured by Toshiba
Sourced in Japan
The Aquilion One Vision Edition scanner is a computed tomography (CT) imaging system manufactured by Toshiba. It is designed to capture high-quality, detailed images of the human body. The core function of this scanner is to provide advanced imaging capabilities for medical professionals to diagnose and monitor various health conditions.
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Lab products found in correlation
3 protocols using aquilion one vision edition scanner
1
Comparative Chest and Cardiac CT Imaging
2
Chest CT Scan Protocol Specifications
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In addition to the physical exam, participants were offered a CT scan of the chest. All CT scans were performed on an Aquilion One Vision Edition scanner (Toshiba Medical Systems, Otawara-shi, Japan) at the Department of Radiology, Rigshospitalet, Copenhagen, Denmark. The following settings were used for image acquisition: 120 kVp, automated exposure control (SD15) and reconstruction with filtered back projection and a soft tissue kernel (1mm slice thickness and 1mm increment). Scans were obtained during a deep inspiratory breath-hold and included the entire lungs. The entire protocol used for spiral image acquisition in chest CT scans has been described in details elsewhere (16 (link)).
3
Spirometry and Chest CT Imaging in PLWH
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The procedure for spirometry has been previously described [17, 18] . An EasyOne® spirometer (ndd Medical, Zürich, Switzerland) was used in accordance with American Thoracic Society/European Respiratory Society guidelines [22] . Predicted values and their lower limit of normal (LLN), i.e. the fifth percentile of the reference population, were calculated using multi-ethnic prediction equations provided by the Global Lung Function Initiative [23] . Airflow limitation was defined as either forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) below the LLN or FEV1/FVC <70% with FEV1 <80% predicted.
CT scanning procedure PLWH and uninfected controls underwent a chest CT scan using the same two scanners at the same location (Department of Radiology, University Hospital of Copenhagen, Copenhagen, Denmark). Details regarding the scan protocol have previously been described [17, 24] (link). In brief, an Aquilion One Vision Edition scanner (Toshiba Medical Systems, Otawara-shi, Japan) was used for image acquisition with the following settings: 120 kVp, automated exposure control (SD15), and reconstruction with filtered back projection and a soft tissue kernel (1 mm slice thickness and 1 mm increment). Scans were acquired during a deep inspiratory breath-hold using spiral image acquisition including the entire lungs.
CT scanning procedure PLWH and uninfected controls underwent a chest CT scan using the same two scanners at the same location (Department of Radiology, University Hospital of Copenhagen, Copenhagen, Denmark). Details regarding the scan protocol have previously been described [17, 24] (link). In brief, an Aquilion One Vision Edition scanner (Toshiba Medical Systems, Otawara-shi, Japan) was used for image acquisition with the following settings: 120 kVp, automated exposure control (SD15), and reconstruction with filtered back projection and a soft tissue kernel (1 mm slice thickness and 1 mm increment). Scans were acquired during a deep inspiratory breath-hold using spiral image acquisition including the entire lungs.
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