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Sonata vision

Manufactured by Siemens
Sourced in Germany

The Sonata Vision is a high-performance laboratory equipment designed for advanced imaging and analysis. It utilizes cutting-edge ultrasound technology to capture detailed and precise visual data from various samples. The core function of the Sonata Vision is to provide users with a versatile and reliable tool for conducting comprehensive analysis and research across a wide range of applications.

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9 protocols using sonata vision

1

Retrospective MRI Study of Sacroiliac Joints

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A dataset composed of oblique axial Short Tau Inversion Recovery (STIR) and Proton Density Fat Saturated (PD-FS) measurements of n = 177 individuals was used (Figure 1). The images were acquired using a 1.5 T MR scanner (Vision/Sonata, Siemens, Erlangen, Germany) between January 2017 and September 2021. They were subsequently retrieved from the PACS of the University Hospital of Heraklion in September 2021 in a retrospective manner. The exclusion criteria included tumors extending to the sacroiliac joints, septic sacroiliitis, previous radiotherapy, and cases with traumatic or insufficiency pelvic fractures. All other sacroiliac joint examinations from our database were included in the study. It is important to note that this study adhered to the principles outlined in the Declaration of Helsinki and received institutional review board approval; informed consent was waived due to the retrospective anonymized nature of the study. Interestingly, no scan was excluded based on image quality or the presence of artifacts. This approach was taken to ensure that the algorithm we developed was trained and tested under conditions that mirrored real-world practice as closely as possible.
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2

Multimodal Brain Imaging Protocol

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All participants underwent brain MRI scans at the MRI Unit, University Hospital of Heraklion using identical scanning parameters. MRI scans were acquired on a clinical, upgraded 1.5T whole-body superconducting imaging system (Vision/Sonata, Siemens/Erlangen), equipped with high performance gradients (Gradient strength: 40 mT/m, Slew rate: 200 mT/m/ms), and a two-element circularly polarized head array coil (minimum voxel dimensions: 70 μm × 70 μm × 300 μm). The main imaging protocol consisted of a 3D T1-w MPRAGE (TR/TE: 1570/1.73 ms, 1 mm/1 NEX/160 axial sections), a T2wTSE (TR/TE: 5000/98 ms, 4 mm axial sections), and a Turbo FLAIR (TR/TE/TI: 9000/120/2320 ms, 4 mm axial sections) sequence. Axial sections were acquired parallel to the plane passing through the anterior and posterior commissures (AC–PC line). Structural MR images were interpreted by a senior neuroradiologist (Dr E. Papadaki, MD, PhD) with 20 years of experience. Rs-fMRI sequences were acquired using a T2*-weighted, fat-saturated 2D-FID-EPI sequence with repetition time (TR) 2320 ms, echo time (TE) 50 ms, field of view (FOV) 192 × 192 × 108 (x, y, z). Whole brain 3D images consisted of 36 transverse slices with 3.0-mm slice thickness and no interslice gap. Voxel BOLD time series consisted of 150 dynamic volumes, while the voxel size was 3 × 3 × 3 mm. Acquisition duration was ~ 6 min.
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3

Multimodal MRI Examination of SLE Patients

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Brain MRI examinations were performed on a clinical 1.5 T MRI scanner (Vision/Sonata, Siemens/Erlangen), equipped with high-performance gradients (Gradient strength: 40 mT/m, slew rate: 200 mT/m/ms) and a two-element circularly polarised head array coil. Conventional MRI protocol consisted of a three-dimensional T1-weighted MPRAGE, a T2-weighted turbo spin echo, a turbo fluid-attenuated inversion recovery, a gradient echo and a diffusion-weighted imaging sequence. Images were interpreted by a senior neuroradiologist (EP), with 20 years of experience, blinded to the clinical and laboratory data, who reported any incidental findings not related to SLE, or findings related to focal SLE-related abnormalities, such as acute or old infarcts, haemorrhages and focal brain atrophy.
rs-fMRI was derived from a T2*-weighted, fat-saturated two-dimensional FID-EPI sequence (TR=2300 ms, TE=50 ms, FOV=192×192×108 mm). Acquisition voxel size was 3×3×3 mm, and whole-brain scans consisted of 36 transverse slices acquired parallel to the plane passing through the anterior and posterior commissures (AC-PC line with 3.0 mm slice thickness and no interslice gap).
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4

Olfactory Bulb and Sulcus Morphometry

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All 40 subjects and 22 controls underwent MRI of olfactory apparatus on a 3 Tesla MR system (Sonata Vision; Siemens, Germany) using the CP-head coil. All the MRIs were reported by a single, experienced radiologist blindfolded for clinical findings. Volumes of the right and left OBs were determined using MRI scans of the olfactory apparatus and a standardized protocol for OB analysis. The protocol included 2-mm T2-weighted constructive interface at steady state (CISS) in the coronal plane covering the anterior and middle segments of the base of the skull. The bulb area was measured in consecutive slices and added, and then multiplied with the slice thickness to obtain its volume. If no bulb was identified on MRI, it was termed as aplasia and the volume was considered as zero. The maximum olfactory sulcus depth (OSd) was measured using the coronal images, while the olfactory sulcus length (OSl) was measured on axial images [Figure 1a and b]. An immeasurable or absent sulcus was considered aplastic. The OB of the patient was considered hypoplastic if its volume was less than mean minus two standard deviations of the control subjects. OS was considered hypoplastic if either OSl or OSd or both were lower than mean minus two standard deviations of the control subjects.[4 (link)10 (link)]
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5

MRI Protocols for Ventricular Assessment

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MRI protocols and acquisitions used for the assessment of ventricular volumes and flow have been previously published by our group in detail [20 (link), 21 (link)]. In brief, studies were performed using a 1.5-T MR scanner [Magnetom Avanto (or SonataVision), Siemens, Erlangen, Germany]. After single-shot localizer images, short-axis cine loop images with breath holding in expiration were acquired using a retrospectively gated balanced steady-state free precession sequence. Two-dimensional velocity encoded MRI flow measurements, perpendicular and directly cranial to the pulmonary and aortic valve, were performed using 2-D gradient echo Fast Low Angle SHot (FLASH), acquired during normal respiration with retrospective cardiac gating.
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6

Olfactory Bulb Volume and Sulcus Depth Measurement

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Patients underwent the MRI of the olfactory apparatus (MRI-OA) on a 3-T MR system (Sonata Vision; Siemens, Germany) using the eight-channel coil. All the MRIs were reported by a single, experienced radiologist blindfolded for clinical findings. Volumes of the right and left olfactory bulbs (OBs) were determined using MRI scans of the olfactory apparatus and a standardized protocol for OB analysis. OB volumes (OBVs) were calculated by planimetric manual segmentation technique (surface in mm2), and all surfaces were added and multiplied by 3.6 because of the 3-mm slice thickness and the 0.6-mm gap to obtain a volume in cubic millimeters. If no bulb was identified on MRI, the volume was considered as zero. The olfactory sulcus depth (OSD) was measured using the coronal images. An immeasurable or absent sulcus was considered as zero.
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7

Pituitary Tumor Evaluation via MRI

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Patients underwent MRI of pituitary, on a 1.5 T MR system (Sonata Vision; Siemens, Erlangen, Germany) using eight channel circularly polarised head coil. All the images (baseline and follow-up) were reported by a single experienced radiologist in a predefined format. Knosp classification system was used to quantify invasion of the cavernous sinus, in which, grade 3 and grade 4 defined true invasion of the tumour into the cavernous sinus. Grade 0–2, where the tumour does not extend beyond the lateral margin of the internal carotid artery (ICA) were labeled noninvasive (5) (link). After starting medical management, MRI was repeated at 6 months, 12 months and subsequently as per the response in an individual patient. Tumour shrinkage was evaluated as the reduction of the maximal dimension and tumour volume compared with baseline. Tumour volume was calculated as π/6×height×length×width of the tumour (6) .
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8

Multi-Center MRI Protocol for Brain Imaging

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In all centers MR images were acquired around TEA. A 3.0 Tesla MR system (Philips Healthcare, Best, The Netherlands) using a sense head coil was available at three centers (University Medical Center Utrecht (UMCU), University Medical Center Leiden and Isala Hospital, Zwolle) and from 2014 onwards at Southmead Hospital, Bristol. Until April 2014, a 1.5-Tesla MR system (GE Signa Excite HD system, USA) was used in Bristol. University Medical Center Groningen (SonataVision, Siemens, Germany), University Hospital Puerta del Mar, Cadiz (Magnetom Symphony, Siemens, Germany), Radboud University Nijmegen Medical Centre (Magnetom Symphony, Siemens, Germany), University of Rotterdam (GE Signa Excite HD system, USA) and University of Lisbon (Philips Healthcare, Best, The Netherlands) used a 1.5 Tesla MR system. All participating centers used conventional axial 3D T1weighted imaging and T2-weighted imaging and followed a predefined MRI protocol according to their institutional guidelines during the study period. Only the high-quality images that were suitable for scoring and volumetric measurements were included in the study.
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9

Cortical Thickness Analysis of MRI Scans

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MRIs were acquired on a 1.5-T Siemens SonataVision (Siemens, Malvern, Pennsylvania), with a high-resolution T1 threedimensional magnetization-prepared Flair sequence (slice thickness = 1 mm isotropic; repetition time = 22 ms; echo time = 9.2 ms; flip angle = 30 • ). Cortical thickness analyses were completed using the automated analysis pipeline CIVET 1.1.12 [1] available via the CBRAIN interface [32] . All images were processed according to CIVET guidelines (for details and references see SI).
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