Four channel array rat head surface coil

To define the anatomical volume of interests (VOIs), MR scans were obtained on a 31-cm horizontal-bore Agilent 9.4 T scanner (Agilent Technologies, Santa Clara, CA, USA) using a four-channel array rat head surface coil (Rapid Biomedical GmbH, Rimpar, Germany). The image parameters for the 3D turbo spin-echo (TSE) T2-weighted images were as follows: repetition time (TR) = 2,500 ms; echo time (TE) = 7.45 ms; field of view = 20 mm × 20 mm × 10 mm; matrix size = 128 × 128 × 64; voxel size = 156 μm × 156 μm × 156 μm; echo train length = 43; and scan time = 1 h 54 min 50 s. During imaging, the respiratory rate of the rats was monitored using an MR-compatible physiological monitoring and gating system (SA Instruments, Inc., Stony Brook, NY, USA).

To define the anatomical VOIs, MR scans were obtained on a 31-cm horizontal-bore Agilent 9.4 T scanner (Agilent Technologies, Santa Clara, CA, USA) using a four-channel array rat head surface coil (Rapid Biomedical GmbH, Rimpar, Germany). The image parameters for the 3D turbo spin-echo (TSE) T2-weighted images were as follows: repetition time (TR) = 2500 ms; echo time (TE) = 7.45 ms; field of view (FOV) = 20 mm × 20 mm × 10 mm; matrix size = 128 × 128 × 64; voxel size = 156 μm × 156 μm × 156 μm; echo train length (ETL) = 43; and scan time = 1 h 54 min 50 s. During imaging, the respiratory rate of rats was monitored using an MR-compatible physiological monitoring and gating system (SA Instruments Inc., Stony Brook, NY, USA).