Parteck delta m

Manufactured by Merck Group

Sourced in France, Germany

Parteck® Delta M is a laboratory equipment product from Merck Group. It is designed to perform material characterization and analysis tasks. The core function of Parteck® Delta M is to provide accurate and reliable measurements of various physical and chemical properties of materials.

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Lab products found in correlation

Parteck m200, by Merck Group (2 mentions) Pearlitol 160 c, by Roquette (1 mentions) Avicel ph 101, by FMC Biopolymer (1 mentions) Avicel ph301, by FMC Biopolymer (1 mentions) Avicel ph105, by FMC Biopolymer (1 mentions) Aerosil 200, by Evonik (1 mentions) Kollidon k30, by BASF (1 mentions)

2 protocols using parteck delta m

Mannitol Powder Particle Size Effects

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β mannitol (Pearlitol^® 160C) was acquired from Roquette Frères (Lestrem, France), and δ mannitol (Parteck^® Delta M) and spray granulated β mannitol (Parteck^® M200) were supplied by Merck KGaA (Darmstadt, Germany). Magnesium stearate was purchased from Peter Greven (Bad Münstereifel, Germany). All powders were sieved through a 1 mm sieve using a Turbosieve BTS 100 (L.B. Bohle, Ennigerloh, Germany) with a speed of 355 rpm. The influence of initial powder particle size on granules and tablet properties was investigated by comparison of two different particle size distributions of β mannitol powder: the initial 1 mm turbosieved powder and a fraction smaller than 180 µm of the β mannitol (180 β mannitol) powder. Therefore, after sieving with the turbosieve, a fraction of Pearlitol^® 160C powder was again manually sieved through a sieve with a mesh size of 180 µm (Retsch GmbH, Haan, Germany) before further processing.

Mareczek L., Riehl C., Harms M, & Reichl S. (2022). Understanding the Multidimensional Effects of Polymorphism, Particle Size and Processing for D-Mannitol Powders. Pharmaceutics, 14(10), 2128.

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Formulation and Characterization of Tablet Excipients

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Microcrystalline cellulose (Avicel PH101, Avicel PH105, Avicel PH301, FMC Biopolymer, Philadelphia, USA), α-lactose monohydrate (Pharmatose 200M, Pharmatose 350M, DFE Pharma, Goch, Germany and GranuLac 200, Meggle Group, Wasserburg, Germany) and mannitol (Parteck M200, Parteck Delta M, Merck, Darmstadt, Germany) were used as fillers. Hydroxypropyl methylcellulose (Pharmacoat 603, Shin Etsu, Tokyo, Japan) and polyvinylpyrrolidone (Kollidon K30, BASF, Ludwigshafen, Germany) were used as binders in this study. Croscarmellose sodium (Disolcel GF, Mingtai Chemical Co, Taoyuan Hsien, Taiwan), magnesium stearate (Mallinckrodt, St. Louis, USA) and colloidal silicon dioxide (Aerosil 200, Evonik, Rheinfelden, Germany) were used to prepare the final blend for tablet compression.

Willecke N., Szepes A., Wunderlich M., Remon J.P., Vervaet C, & De Beer T. (2018). A novel approach to support formulation design on twin screw wet granulation technology: Understanding the impact of overarching excipient properties on drug product quality attributes. International journal of pharmaceutics, 545(1-2).

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