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Mmtv neu tg

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The MMTV-Neu-Tg is a transgenic mouse model that expresses the rat Her2/neu oncogene under the control of the mouse mammary tumor virus (MMTV) promoter. This model is used in cancer research to study the role of the Her2/neu oncogene in the development and progression of breast cancer.

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Lab products found in correlation

Fvb nj, by Jackson ImmunoResearch (3 mentions) Nod cg prkdcscid il2rgtm1wjl szj, by Jackson ImmunoResearch (3 mentions) C3 1 sv40 tg, by Jackson ImmunoResearch (3 mentions) C57bl 6, by Jackson ImmunoResearch (3 mentions)

Spelling variants of this product

MMTV-Neu (6 citations) MMTV-Neu (FVB/N-Tg(MMTVneu)202Mul/J, (3 citations) Strain FVB/N-Tg (MMTV-Neu) 202 Mul/J (2 citations) Balb/c-Tg (MMTV-neu) (2 citations)

4 protocols using mmtv neu tg

1

Mouse Strains for Cancer Research

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Balb/cAnNCr (Stock #01B05) mice were obtained from the National Cancer Institute. FVB/NJ (Stock #001800), MMTV-Neu-Tg (Stock #005038), athymic Balb/c (Nu/Nu, Stock #007870) and NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (Stock #00557) mice were obtained from Jackson Laboratories. All these mice were bred and maintained in Augusta University Animal Facility in accordance with the guidelines of the Institutional Animal Care Use Committee.
Pathania R., Ramachandran S., Mariappan G., Thakur P., Shi H., Choi J.H., Manicassamy S., Kolhe R., Prasad P.D., Sharma S., Lokeshwar B.L., Ganapathy V, & Thangaraju M. (2016). Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth. Cancer research, 76(11), 3224-3235.
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2

Diverse Transgenic Mouse Models

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FVB/NJ (Stock # 001800), C57BL/6 (Stock # 000664), MMTV-Neu-Tg (Stock # 002376) NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (Stock #00557) and C3(1)-SV40-Tg (Stock # 013591) mice were obtained from Jackson laboratories. All these mice were bred and maintained in Georgia Regents University Animal Facility in accordance with the guidelines of the Institutional Animal Care Use Committees.
Pathania R., Ramachandran S., Elangovan S., Padia R., Yang P., Cinghu S., Veeranan-Karmegam R., Arjunan P., Gnana-Prakasam J.P., Fulzele S., Pei L., Chang C.S., Choi H., Shi H., Manicassamy S., Prasad P.D., Sharma S., Ganapathy V., Jothi R, & Thangaraju M. (2015). DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis. Nature communications, 6, 6910.
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3

Mouse Models for Cancer Research

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C57BL/6 (Stock # 000664), MMTV-PyMT-Tg (Stock # 002374), MMTV-Neu-Tg (Stock # 002376), C3(1)-SV40-Tg (Stock # 013591), and Rad51ap1-knockout [B6N(Cg)-Rad51ap1tm1.1(KOMP)Vlcg/J, Stock # 025176) mice were obtained from the Jackson laboratories. All these mice were bred and maintained in AU Animal Facility in accordance with the guidelines of the IACUC. All euthanasia protocols have performed in accordance with the regulations and guidelines presented by IACUC and LAS of AU.
Bridges A.E., Ramachandran S., Pathania R., Parwal U., Lester A., Rajpurohit P., Morera D.S., Patel N., Singh N., Korkaya H., Manicassamy S., Prasad P.D., Lokeshwar V.B., Lokeshwar B.L., Ganapathy V, & Thangaraju M. (2020). RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal. Cancer research, 80(18), 3855-3866.
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4

Diverse Transgenic Mouse Models

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FVB/NJ (Stock # 001800), C57BL/6 (Stock # 000664), MMTV-Neu-Tg (Stock # 002376) NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (Stock #00557) and C3(1)-SV40-Tg (Stock # 013591) mice were obtained from Jackson laboratories. All these mice were bred and maintained in Georgia Regents University Animal Facility in accordance with the guidelines of the Institutional Animal Care Use Committees.
Pathania R., Ramachandran S., Elangovan S., Padia R., Yang P., Cinghu S., Veeranan-Karmegam R., Arjunan P., Gnana-Prakasam J.P., Fulzele S., Pei L., Chang C.S., Choi H., Shi H., Manicassamy S., Prasad P.D., Sharma S., Ganapathy V., Jothi R, & Thangaraju M. (2015). DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis. Nature communications, 6, 6910.
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